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Biomedical subjects

C Oh

Publications and source records attributed to C Oh.

65 records · Page 4Linked to original sources

One thousand cryohemorrhoidectomies: an overview.

One thousand cryohemorrhoidectomies were performed during the past seven years with the result that one-third of our patients were relatively pain-free while two-thirds complained of severe to minimal pain. The recurrence rate was about 11 per cent but the true incidence was 6.3 per cent. Unpleasant anal discharge, occurring in patients with prolapsed hemorrhoids, can be prevented by ligation prior to freezing. Overall, 90 per cent of our patients were satisfied with the procedure while 6.6 per cent underwent repeated surgery. Comparative analyses were made with other studies and it is fair to say that cryosurgery has definite advantages for selected cases of hemorrhoids, but it is not a panacea for all hemorrhoidal disease.

Adult↗

A biotin-avidin based screening test for methamphetamine in urine.

A biotin-avidin based screening test for methamphetamine in urine samples has been developed. The assay method utilizes the immunoprecipitin reaction between an antibody to methamphetamine and a conjugate prepared by complexing avidin with a biotinyl amphetamine derivative. The rates of the immunoprecipitin reaction is monitored on the Beckman ARRAY 360 nephelometer. Methamphetamine inhibits the precipitin reaction, and the extent of inhibition allows the quantitation of methamphetamine in the urine samples. Using a cut-off value of 0.7 microgram ml-1, the assay correctly predicted 83 of 84 samples (98.8%) confirmed to be positive by GC-MS (> 500 ng ml-1). Of 59 GC-MS confirmed negative samples, 46 samples were found to be negative by this method as compared to 34 samples determined with the EMIT assay. Within-run and between-run relative standard deviations near the cut-off value were less than 4%. Cross-reactivity with amphetamine was < 7%.

Antibodies↗