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Biomedical subjects

C Navarro

Publications and source records attributed to C Navarro.

At least 199 records · Page 11Linked to original sources
PubMed1984

The effects of dietary supplementation during pregnancy on placental morphology, pathology, and histomorphometry.

We related the macroscopic and microscopic morphology and the histomorphometry of the placenta to prenatal nutritional supplementation. In the Prenatal Project, a controlled clinical trial, three dietary treatments (supplement, a high-protein beverage; complement, a balanced protein-calorie beverage, or routine vitamin and mineral tablets) were randomly allocated to poor Black pregnant women, and the outcome was assessed. Herein we report the effects on placental morphology and histomorphometry. There were significantly fewer preterm deliveries in the complement group, and this was reflected by an increase in the size of decidual cells, an index associated with placental aging. Several other characteristics of the placentas of the complement group may have been more directly associated with improved perinatal outcome: decreased intervillous fibrin, lower incidence of gross surface infarct, and smaller (and presumably less edematous) cells of the villous stroma, may have mediated increased placental perfusion. There was no evidence of any placental change associated with the increase in very preterm delivery and the highly significant depressed birth weight among preterm deliveries in the supplement group. The significantly lower incidence of meconium staining of Wharton's jelly among controls seems likely to have been a chance finding. While there were several other indices that reflected placental aging, the significantly increased chorioamnionitis, acute funisitis , and acute decidual inflammation among placentas of those who delivered prematurely [the former two associated with very early delivery (less than 35 wk gestation)] were likely to have been involved as causes of premature delivery.

Clinical Trials as Topic↗
PubMed1983

The effects of three different regimens of oral contraceptives and three different intrauterine devices on the levels of hemoglobin, serum iron and iron binding capacity in anemic women.

The effects on hemoglobin, iron and iron binding capacity (IBC) in 150 moderately anemic women of 1) a 21-day low-dose combined pill, 2) the same low-dose combined pill for 21 days, followed by 7 days of an iron-containing pill, 3) the same low-dose combined pill administered for 63 consecutive days, followed by 7 days of no pill intake, 4) Lippes IUD, 5) TCu 220C and 6) Progestasert were studied. The three pill regimens were associated with an increase in hemoglobin and serum iron after 12 months. However, the iron pill and 63-day schedule groups produced an increase in hemoglobin and iron at the 6th month ans a diminution of IBC at 12 months. The Lippes and TCu 220C groups did not show any change in hemoglobin, iron or iron binding capacity after 12 months. The Progestasert group showed an increase in hemoglobin and iron levels at 6 and 12 months, and a diminution of IBC at 12 months. The pill and Progestasert have advantages as contraceptives in anemic women.

Adolescent↗
PubMed1983

Rhomboid-to-"W" technique for excision and closure of facial skin lesions.

The authors present their experience with the rhomboid-to-W excision technique for cutaneous lesions in the face, its utilization in lesions of more than 20 mm., and a modification of the original method. This type of reconstruction using the adjacent triangular flaps forming a "W", leads to a barely-visible scar. The advantages of this surgical procedure are also enumerated.

Face↗
PubMed1983

[Communication in "functional" and "dysfunctional" families with adolescent children. I. Verbal communication].

This research studies family communications during the critical period of change provoked by the puberty of one of the children. Two groups of families are compared: one group of 15 "functional" families (no psychological consultation has been requested) and one group of 15 "dysfunctional" families (a psychological consultation has been requested for one of the adolescents). The micro-analysis of the verbal communications reveals a few significant differences between the two groups of families. The results point to structural differences between the family systems.

Adolescent↗
PubMed1982

Gas within the wall of the stomach report of a case and review of the literature.

Gas within the stomach wall is a rare occurrence. A case of intramural gas is presented. When air or gas is seen within the gastric wall on x-ray, gastric emphysema, emphysematous gastritis, or pneumatosis intestinalis is diagnosed. These classifications have become vague and contradictory. Gas in the gastric wall can only come from the environment or have been produced within the wall. Gastric emphysema and emphysematous gastritis refer to these situations, respectively. These classifications are expanded and pneumatosis intestinalis is deleted as a clinical or pathological diagnosis.

Aged↗
PubMed1982

Subcortical neglect.

Unilateral neglect is usually caused by lesions of the right cerebral cortex, especially parietal. Neglect after subcortical lesions has been reported rarely in thalamic or striatal hemorrhage, and after infarction of thalamus or striatum and internal capsule shown by CT. In these patients, there may have been compression or ischemia of overlying cerebral cortex and white matter. We report a patient with sensory hemineglect, asomatognosia, and anosognosia caused by infarction of striatum and deep white matter, with involvement of neither cortex nor thalamus and without mass effect. This is the first autopsy-confirmed example of human neglect with involvement of only the striatum and deep white matter.

Aged↗
PubMed1981

The effect of in vivo exposure to diesel exhaust on rat hepatic and pulmonary microsomal activities.

The effect of exposure to three concentrations of diesel exhaust on several heptic and pulmonary activities has been tested. After one year of exposure, the ability of liver microsomes to oxidize benzo[alpha]pyrene to more polar metabolites was not increased. Further studies with liver microsomes showed that, after several months of exposure, there was no evidence for the induction of either cytochrome P-450, cytochrome P-448 or NADPH dependent cytochrome c reductase. The ability of pulmonary microsomes to generate polar metabolites from benzo[alpha]pyrene was impaired after one year of exposure to the highest concentration of exhaust (1500 micrograms m-3). The process by which the exposure causes this inhibition is not clear.

Aerosols↗
PubMed1981

Sarcoidosis presenting as senile dementia.

Cerebral sarcoidosis was found at autography in a 68-year-old woman with progressive dementia. Of 35 previously reported cases of central nervous system sarcoidosis with dementia, only 1 was over 65 years old, and in only 2 was the presenting clinical syndrome that of a degenerative dementia. Other unusual features of the index case include the restriction of the initial cognitive deficit to memory loss and mild anomia, the scarcity of antemortem evidence for systemic sarcoidosis, a positive tuberculin test, a cerebrospinal fluid (CSF) protein concentration as high as 2028 mg per deciliter. sarcoidosis is a rare but potentially treatable cause of dementia. Consistently normal CSF probably excludes the diagnosis.

Aged↗
PubMed1981

Charcot-Marie-Tooth's disease with severe trophic and sensory disorders. Study of a case following along a half a century with anatomical studies.

Plantar ulcers of neurological origin are known to be associated with several disorders, some of which may be familial. We present the case report together with the clinical and post-mortem data of a patient with peroneal muscular atrophy of the Charcot-Marie-Tooth type and plantar ulcers as a prominent feature. At least three other members of her family had Charcot-Marie-Tooth disease. The family pedigree is included. The discussion stresses the difference between patients with Charcot-Marie-Tooth disease with associated manifestations, bony destruction of the feet and plantar ulcers and patients with hereditary motor and hereditary sensory radicular neuropathies.

Charcot-Marie-Tooth Disease↗
PubMed1980

[Hypokalemic periodic paralysis. Report of two cases (author's transl)].

The familial periodic hypokalemic paralysis is an infrequent disease characterized by paralytic attacks of sudden appearance affecting the muscles of the trunk and limbs. There is a marked hypokalemia during the paralytic episodes of the disease, and a family history in 80 percent of the cases. The differential diagnosis includes hyperthyroidism with periodic paralysis, congenital paramyotony and adynamia episodica hereditaria. Two typical cases of hypokalemic periodic paralysis are presented, with biological, electrophysiological, clinical, and ultrastructural pictures characteristics of the disease. The clinical manifestations of both patients are discussed, stressing the diagnostic importance of the electrophysiological study during the insulin test, and the interest of the histologic and ultrastructural studies. The spectacular response during the acute episodes to the intravenous perfusion of potassium salts, and the usefulness of the acetazolamide administration to prevent the paralytic episodes are emphasized.

Adolescent↗
PubMed1980

Diffuse intrapulmonary hemorrhage, renal failure and a systemic vasculitis. A case report and review of the literature.

A 63 year old women was hospitalized with massive hemoptysis, anemia and renal failure. Despite intensive supportive care, she died soon after admission. Autopsy revealed diffuse necrotizing alveolitis, rapidly progressive glomerulonephritis and a systemic vasculitis. Massive intrapulmonary hemorrhage with hemoptysis is an unusual complication of a systemic vasculitis. The case is discussed and the literature reviewed.

Acute Kidney Injury↗
PubMed1980

Cardiovascular activity of a deproteinized blood extract.

The cardiovascular effects of the deproteinized blood extract were investigated in anaesthetized dogs: respiration, general metabolism and systemic haemodynamics were tested and the changes in these parameters after the administration of the drug were studied. At 2 ml kg-1 i.v., the deproteinized blood extract induced a transient drop in arterial blood pressure and bradycardia. On the other hand, the total peripheral resistance and the elastic resistance, of the arteries were decreased and this effect was of longer duration. Moreover, the deproteinized blood extract stimulated the myocardium contractile force and dc/dt and increased the cardiac performances. The mechanism of action of this drug is discussed.

Animals↗
PubMed1980

[Incidence of renal involvement in Schönlein-Henoch syndrome (author's transl)].

To determine the incidence of renal involvement in Schönlein-Henoch syndrome, authors enrolled in a prospective study all children admitted with this diagnoses from 1971 through 1978. They followed-up 112 patients, which represented the 2 per one thousand of the total hospital pediatric admission in the same period; 22 patients (19.6%) developed renal involvement. After two years of follow-up they observe one patient with progressive renal failure, four with minor urinary abnormalities and 17 asymptomatics. The single patient with renal failure represents the 4.5% of the patients with Schönlein-Henoch nephropathy and the 0.9% of the total affected with this syndrome.

Child↗