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Biomedical subjects

C Moore

Publications and source records attributed to C Moore.

At least 307 records · Page 17Linked to original sources
PubMed1977

An unusual presentation of carcinoma of the lung: 26 patients with cervical node metastases.

Carcinoma of the lung should be considered in the search for an unknown primary lesion when there is evidence of cervical lymph node involvement. Of 1,686 patients with a final diagnosis of bronchogenic carcinoma seen during a 10-year period at the University of Louisville Hospitals, 26 presented one or more clinically positive cervical nodes. The frequency of lung cancer in such instances varies from 1.5% (in the present report) to 32%, possibly because the term "cervical node" is used without clarification. More precise description of such metastases is urged.

Carcinoma, Bronchogenic↗
PubMed1977

Spliced segments at the 5' terminus of adenovirus 2 late mRNA.

An mRNA fraction coding for hexon polypeptide, the major virion structural protein, was purified by gel electrophoresis from extracts of adenovirus 2-infected cells late in the lytic cycle. The mRNA sequences in this fraction were mapped between 51.7 and 61.3 units on the genome by visualizing RNA-DNA hybrids in the electron microscope. When hybrids of hexon mRNA and single-stranded restriction endonuclease cleavage fragments of viral DNA were visualized in the electron microscope,branched forms were observed in which 160 nucleotides of RNA from the 5' terminus were not hydrogen bonded to the single-stranded DNA. DNA sequences complementary to the RNA sequences in each 5' tail were found by electron microscopy to be located at 17, 20, and 27 units on the same strand as that coding for the body of the hexon mRNA. Thus, four segments of viral RNA may be joined together during the synthesis of mature hexon mRNA. A model is presented for adenovirus late mRNA synthesis that involves multiple splicing during maturation of a larger precursor nuclear RNA.

Adenoviridae↗
PubMed1975

Management of patients who overdose.

People who overdose appear to arouse a mixture of emotions in their attending doctors, some of which are associated with feelings of inadequacy on the doctors' part. If this group of people is approached in a logical and emotionally neutral faxhion, the problem becomes essentially a manageable one. Perhaps most importantly, by this method a reasonably accurate prediction can be made of whether the person will repeat this pattern of abnormal behaviour.

Family Practice↗
PubMed1975

Sebaceous cyst extraction through mini-incisions.

A method for removing sebaceous cysts through a mini-incision using 5 per cent phenol is described. It is recommended for selected cases where it is important to leave the minimal surgical scar.

Cicatrix↗