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Biomedical subjects

C M Boyd

Publications and source records attributed to C M Boyd.

90 records · Page 5Linked to original sources

Lingual thyroid: unusual appearance on computed tomography.

A patient with a lingual thyroid was found to have inhomogeneous contrast enhancement on CT, findings not previously reported. Operative and histologic examination revealed marked thyroiditis and goitrous changes, explaining the CT findings.

Adolescent↗

CT findings in abdominal actinomycosis.

The diagnosis of abdominal actinomycosis is difficult because of its relative infrequency and imitation of other diseases. We present four cases in which these difficulties in diagnosis were experienced and show the utility of CT in suggesting this disease. Aspiration, biopsy, and proper culture technique, in conjunction with typical CT findings of transfascial and multiple organ involvement, led to the proper diagnosis in all cases.

Abdomen↗

Mechanical induction of osteogenesis: the importance of pin rigidity.

Eight dogs, divided into two groups of four by varying pin rigidity, underwent 15% left tibial lengthening by the Ilizarov method. In group I, "tensioned" 1.6-mm wires maintained a rigidity approaching that of 4.0-mm pins. In group II, the wires, maintained at half the tension, averaged 45% of the rigidity measured in group I. All dogs in group I filled the experimental gap with de novo osteogenesis, whereas all of the dogs in group II prematurely bridged the gap, arresting the process of osteogenesis. From these experimental results, clinical trials have been started using commercially available external fixation devices utilizing pins with equivalent rigidity.

Adolescent↗

Mechanical induction of Osteogenesis. Preliminary studies.

The animal model developed in the Soviet Union by Ilizarov has been reliably reproduced by us for the mechanical induction of osteogenesis using slow distraction. Our preliminary studies in six adult dogs indicate that this osteogenesis originates from well-structured intramembranous ossification, with rapid maturation to lamellar bone, indistinguishable from surrounding host bone. Mineralization increases steadily, reaching critical levels for radiographic visualization between Days 21 and 28. In this model, the osteogenic area then exceeds normal bone density temporarily but returns to normal density within three months. Distraction for 28 consecutive days (at 0.25 millimeters every six hours using rigid transfixion wires, as Ilizarov describes) reliably lengthened the tibiae by 12 percent, increasing mass by 27 percent, and volume by 26 percent with only a one percent change in overall density. The process required four months to add 24 millimeters of mature, lamellar bone capable of full weight-bearing by the dogs. This rate of osteogenesis, estimated at 202 microns per day, is four times faster than a human's fastest growth plate (child's distal femur at 50 microns per day). Calcium/collagen ratios did not differ significantly from normal bone controls.

Animals↗

Lymphoma of the thyroid gland associated with mycosis fungoides: sonographic, scintigraphic and CT features.

A thyroid mass in a 63 year old man with mycosis fungoides, histologically was a not well differentiated B cell lymphoma. Sonographically, it presented as a mass with nonhomogeneous echo pattern along with "target" lesions. On the scintigram, the mass failed to accumulate radioiodine and on the CT it was a nonenhancing lesion. None of these patterns are specific for the disease.

B-Lymphocytes↗

The role of primary and secondary profundaplasty in the treatment of vascular insufficiency.

Profundaplasty has been performed on 58 limbs (45 primary and 13 secondary) in 45 men. Thirty-four of these had incapacitating claudication, 14 rest pain, and 10 either gangrene or ischemic ulceration. In 19 treated by profundaplasty alone there were no deaths but three subsequently had amputation for ischemic pain. In 39 with profundaplasty plus a proximal operative augmentation there were two (6.7%) operative deaths and one (3.4%) late death but only one extremity had to be amputated. Radionuclide flow studies confirmed physical and arteriographic findings. After profundaplasty alone and profundaplasty plus aortofemoral bypass there was moderate increase in calf blood flow but in only those with a patent superficial femoral did the flow studies return to normal. Profundaplasty is an important addition to the armamentarium of the vascular surgeon in dealing with arteriosclerotic insufficiency of the lower extremities.

Aged↗