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Biomedical subjects

C L Barrett

Publications and source records attributed to C L Barrett.

23 records · Page 2Linked to original sources
PubMedDate not supplied

Streptococcal abscesses following diphtheria-tetanus toxoid-pertussis vaccination.

Abscesses developed in seven children who received diphtheria-tetanus toxoid-pertussis vaccine at a clinic in Indiana. Epidemiologic investigation revealed that all seven children had received vaccine from the same multidose vial and had been vaccinated by the same nurse at the office of one physician. Group A beta-hemolytic Streptococcus was isolated from abscesses in six of the seven children. No source was identified as the cause of this cluster of abscesses. Vaccine of the same lot number used elsewhere was not associated with the development of abscesses. It appears that the vaccine became contaminated during use.

Abscess↗
PubMedDate not supplied

Risk factors for hepatitis B virus infection among women attending a clinic for sexually transmitted diseases.

Risk factors for and serologic evidence of hepatitis B virus (HBV) infection were analyzed among 557 women. Study subjects were attending a clinic for sexually transmitted diseases and enrolled in a clinical trial of nonoxynol-9 prevention of gonococcal and chlamydial infections. Seventy-eight (14%) showed serologic evidence of past HBV infection. Only age at time of serum collection was significantly associated with HBV marker prevalence (P = 0.04). None of the four measures of sexual activity taken (number of sex partners per month, frequency of sexual intercourse, number of documented episodes of sexually transmitted diseases, and lifetime number of sexual partners) were significantly related to the presence of HBV markers. For each measure, however, differences observed between HBV positive and negative subjects were consistent with what would be expected if these factors did contribute to HBV infection risk. These results support the role of heterosexual transmission of HBV infection in women and are consistent with recommendations for hepatitis B immunization of heterosexually active persons with multiple sexual partners.

Adult↗
PubMedDate not supplied

The prediction of chronic pain outcome by psychological variables.

Followup telephone interviews were conducted with fifty-four former patients of a multidisciplinary clinic for the evaluation of chronic pain. Interviews were conducted between thirteen and fifty-five months following initial evaluation at the pain clinic. Followup levels of pain and physical disability were compared with the following measures obtained at initial evaluation: levels of pain and physical disability and scores on the Minnesota Multiphasic Personality Inventory (MMPI), McGill Pain Questionnaire (MPQ), and Zung Depression Inventory (ZDI). In general, both physical disability measures and psychological test scores obtained at initial interview were related to followup measures. However, when the predictive value of initial pain and physical disability was accounted for, psychological test scores tended not to produce further significant increment in predictability. These findings are interpreted to mean that the predictive value of these psychological tests stems less from their reflection of a psychological state or attitude with respect to pain, and more from their tendency to reflect ongoing level of pain, disability, and other pain sequelae. The results support the hypothesis that scores on these psychological tests are, at least in part, a reflection of the actual pain and disability and may not be subject to the same clinical interpretations that scores obtained from a psychiatric sample would be.

Adult↗