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Biomedical subjects

C K Tang

Publications and source records attributed to C K Tang.

At least 91 records · Page 5Linked to original sources
PubMed1979

Histoplasmosis of skin and lymph nodes and chronic lymphocytic leukemia.

Nodular skin and cervical lymph node lesions of histoplasmosis, unassociated with systemic symptoms of the infection, developed in a 63-year-old man with untreated chronic lymphocytic leukemia. The histologic patterns in both the skin and lymph node were those of a lymphoproliferative disorder, but Histoplasma organisms were found within a few scattered histiocytes after a careful search. The subtle clinical and pathologic presentation might lead one to overlook the organisms and to believe that the leukemic process had progressed, resulting in potentially dangerous systemic involvement of histoplasmosis and unnecessary chemotherapy for his leukemic process. Complete remission of histoplasmosis was obtained with amphotericin B therapy.

Dermatomycoses↗
PubMed1979

Renal and gastric hamartomas.

This report documents a patient with renal tumor which was originally diagnosed as "Wilms' tumor" and treated by irradiation and chemotherapy. Fifteen years later the patient was found to have gastric hamartomas. Reviews of the kidney tumor revealed it to be composed of morphologic features consistent with renal hamartoma rather than Wilms' tumor. We wish to report this extremely unusual association of renal and gastric hamartomas.

Adolescent↗
PubMed1979

Myxoid adrenal cortical carcinoma: a light and electron microscopic study.

An adrenal cortical carcinoma demonstrating a peculiar myxoid background similar to that of a myxoma was found in a 41-year-old woman who also had parathyroid hyperplasia and clinical evidence of a pituitary tumor. The electron microscopic study demonstrated its value in establishing the diagnosis that was not possible to make with absolute certainty at the light microscopic level alone. The combination of endocrine disorders strongly suggests the possibility of an unusual multiple endocrine syndrome.

Adrenal Cortex Neoplasms↗
PubMed1978

Trabecular carcinoma of the skin: an ultrastructural study.

We report the electron microscopic studies of three trabecular carcinomas of the skin. The presence of neurosecretory granules in all three tumors suggests that trabecular carcinoma originates from one of the neurocrest derivatives, most probably, Merkel cells. The ultrastructural findings confirm Toker's original concept that trabecular carcinomas comprise a distinct group of skin tumor. The recognition of these tumors would enable one to make such a diagnosis on frozen section, which, in turn, might provide an opportunity for more specific cytochemical and immunofluorescent characterization.

Adenocarcinoma↗
PubMed1978

Glomangioma of the lung.

An unusual pulmonary tumor was identified on the basis of light and electron microscopic findings as glomangioma. The ultrastructural findings of intracytoplasmic fibrils with dense bodies, electron-dense plaques, pinocytotic vesicles, and basement membranes are consistent with smooth muscle origin. The differential diagnosis between our tumor and other unusual tumors is discussed. The occurrence of a glomangioma in the lung may indicate the existence of pulmonary glomera.

Aged↗
PubMed1978

Tracheobronchial cytologic changes in malignant melanoma.

Histiocytes counted in smears made from the tracheobronchial washings of 208 patients with malignant melanomas were found to be 3.12 times more numerous than in a control group comparable in sex, age (decades), and smoking habit but without any type of prediagnosed malignant lesion. The discovery of this phenomenon may lead to the development of a new method for the evaluation of therapeutic methods in patients with melanotic lesions. It may open novel pathways for the investigation of cell-mediated immunity in patients with certain forms of malignant disease.

Adolescent↗
PubMed1978

Home treatment of uremia with gastrointestinal dialysis.

Twenty patients with end-stage renal disease and a creatinine clearance of less than 5 ml/min were tre ated with oral gastrointestinal (GI) dialysis. The dialyzate contained an electrolyte solution with 180-220mmoles/l of mannitol. In fasting state in the morning the self-prepared 7 liters of dialyzate was drunk at a rate of one glass every 5 minutes for about 3 hours. Intermittent diarrhea with passage of watery fluid occurred during the whole period. After each treatment the average drop in BUN in individual patients was 11--22%, but no significant decrease in serum creatinine. With twice to thrice weekly GI dialysis uremic symptoms such as anorexia, nauseal and vomiting were usually improved with slight prolongation of life. However, treatment is usually difficult when the patient becomes oliguric or anuric, so its value in long-term management of chronic uremia is limited. Most of our patients either died or shifted to hemodialysis within a few months of institution of the therapy.

Adult↗
PubMed1977

Solitary cystic lymphangioma of the retroperitoneum.

We present 2 cases of solitary cystic lymphangioma of the retroperitoneum. The non-specific clinical picture is demonstrated again but the pathologic features of both tumors are characteristic. Surgical treatment was successful in both instances.

Child, Preschool↗
PubMed1976

Acute massive hemorrhage from intestinal Crohn disease. Report of seven cases and review of the literature.

Acute massive intestinal bleeding from Crohn disease occurred in 1.4% of 503 patients undergoing treatment at the New York Hospital-Cornell Medical Center over a 43-year period. Of the entire series, 31% had clinically evident rectal bleeding, while 13% had occult bleeding. Combined with previously reported series, onset of massive bleeding was not influenced by age of patient, duration of Crohn disease, use of corticosteroids, or activity of disease. Surgical therapy gave satisfactory results in patients with life-threatening hemorrhage.

Adolescent↗
PubMed1975

Adrenocortical neoplasms. Prognosis and morphology.

The clinical data and morphologic findings in 16 cases of adrenocortical carcinoma were compared with those in 11 cases of surgically removed functional adenomas and 12 cases of nonfunctional adenomas found at autopsy. Histopathologic changes of architectural disarray, pleomorphism, increased mitotic activity, vascular invasion, hemorrhage, or necrosis were generally reliable criteria for diagnosis of malignancy. However, weight was the parameter that most consistently correlated with outcome, since all patients with tumors under 50 Gm. survived and all lesions of 95 Gm. or over proved to be malignant.

Adenoma↗
PubMed1975

Leiomyosarcoma of the colon exclusive of the rectum.

Five cases of leiomyosarcoma of the colon are presented along with a review of the literature. In our cases the presenting symptoms and signs included abdominal pain, diarrhea, weight loss, blood in stools and abdominal mass. Anemia was present in four cases. Roentgenologically, an intraluminal tumor with obstruction was found in two cases, paralytic ileum in one and two cases were reported as "negative". At surgery there were peritoneal implants in three cases, metastases to the liver in two cases and perforation of the tumor in one case. Only diagnostic or palliative surgery was performed in all cases. All patients died of tumor within 15 months. The clinicopathological findings are similar to those reported by others in patients with extensive disease.

Adult↗