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Biomedical subjects

C K Hayden

Publications and source records attributed to C K Hayden.

At least 37 records · Page 2Linked to original sources

Abnormalities of the neonatal brain: MR imaging. Part II. Hypoxic-ischemic brain injury.

Eighty-five infants, 82 of whom were 29-44 weeks postconceptional age, were imaged with a 0.6-T magnet. Eight infants had cerebral infarction. In premature neonates with very water, low-intensity white matter on T1-weighted images, ultrasound was better than both computed tomography and magnetic resonance (MR) imaging in depicting parenchymal changes of infarction or edema. However, after 37 weeks gestation, MR imaging was superior. Cerebral atrophy, present in seven infants, was consistent with subarachnoid space widths of 7 mm or more, or subarachnoid space widths of 5-6 mm with ventricular/brain ratios of 0.36 or greater. Delayed myelination was seen in a total of 18 infants with histories of hypoxic-ischemic insult. MR imaging shows promise in the neonatal period. It facilitates recognition of infarcts in full-term infants and may be used to predict abnormal neurologic outcome in infants who have initial delayed myelination.

Atrophy↗

Gastric ulcer disease in infants: US findings.

Among 600 infants examined with ultrasound for vomiting, seven (mean age, 3 months) had distinctive features that can be considered diagnostic of gastric ulcer. The findings are thickening of the mucosa (greater than 4 mm) in the antropyloric region, elongation of the antropyloric canal, persistent spasm, and delayed gastric emptying. Two of the infants had slight thickening of the pyloric muscle. Gastrointestinal series or endoscopy demonstrated thickened gastric mucosa and a deformed gastric antrum in all infants, as well as actual ulceration in five.

Chronic Disease↗

Viral vs. bacterial pulmonary infections in children (is roentgenographic differentiation possible?).

This study was conducted to determine whether one could identify viral and bacterial pulmonary infections with confidence. It has been our impression for some time that one could differentiate viral from bacterial pulmonary infections on the basis of roentgenographic findings alone and to test this hypothesis, we conducted this study where the roentgenographic findings first were categorized as being due to viral or bacterial infection and then compared with clinical results. The overall accuracy was just over 90% and our method of analysis is presented.

Adolescent↗

Pyogenic liver abscesses in nonimmunocompromised children.

Pyogenic liver abscesses are rare in previously healthy children. This review reports ten such cases of pyogenic abscess seen between 1963 and 1984. The mean age in these children was 6.3 years. One child died. Of the nine survivors, five had successful open surgical drainage. Two abscesses were drained percutaneously. Another abscess drained spontaneously into the biliary system, and one abscess was treated with antibiotics alone. The single most helpful diagnostic test was abdominal ultrasonography. Our experience is evaluated in the context of other reports of pyogenic abscesses in children.

Adolescent↗

Renal cystic disease in childhood.

The authors present a comprehensive review of the diagnostic features of eight forms of renal cystic disease that occur in childhood. Sonographic findings are emphasized.

Child↗

Intussusception: indications for ultrasonography and an explanation of the doughnut and pseudokidney signs.

Ultrasonography has been shown to be valuable in the detection of intussusception, but a question arises, as to just when this study should be performed. Should it be a general screening procedure or should it be utilized for specific cases only? Upon reviewing the literature, and the findings in 14 of our patients, we feel that it should be utilized as a general screening procedure. In addition, we offer a different explanation for the typical doughnut and pseudokidney signs seen with intussusception.

Child, Preschool↗

Abdominal masses in children.

The authors examine the effects of ultrasound on the diagnosis and treatment of abdominal masses in children. Some of the newer imaging modalities may also be required on a selective basis. All in all, these modalities have led to a completely new approach to abdominal masses in children.

Abdominal Neoplasms↗

Subependymal germinal matrix hemorrhage in full-term neonates.

A population of healthy, full-term newborn infants was studied in order to obtain documentation of the prevalence of intracranial hemorrhage. Cerebral ultrasonography was performed within 72 hours of birth on 505 healthy newborn infants, 37 weeks of gestation or greater. Sonographic abnormalities were detected in 23 (4.6%) neonates. Bilateral subependymal germinal matrix hemorrhage occurred in 14 and unilateral hemorrhage in five infants. Other abnormalities detected included agenesis of the corpus callosum in two infants, a cyst involving the subependymal germinal matrix in one (presumably the result of a previous subependymal hemorrhage), and mild ventricular dilation of unknown etiology in one. Newborns with subependymal hemorrhage were compared with newborns without hemorrhage in order to determine whether any significant differences existed between the two populations. No significant differences existed between infants with and without subependymal hemorrhage with regard to gender, obstetrical presentation, use of forceps, birth trauma, Apgar scores, need for resuscitation, maternal age and parity, and neonatal clinical problems. Infants with subependymal hemorrhage were of significantly lower gestational age and birth weight; the overall difference in weight was attributable to lower weight in female infants with subependymal hemorrhage. Significantly more infants with subependymal hemorrhage were small for gestational age, vaginally delivered, and black.

Birth Weight↗

Filiform polyposis in a child with Crohn's disease.

Filiform polyps were demonstrated radiographically in a seven year old child with granulomatous colitis. Most previous reports have been in adult subjects. These slender projections of colonic mucosa and submucosa have a characteristic radiographic appearance on barium enema. It is important to recognize the condition as being benign.

Barium Sulfate↗

Systemic-pulmonary shunting and hemoptysis in a benign intrathoracic teratoma.

Hemoptysis as a presenting symptom in benign intrathoracic teratoma is rare, but we have documented one such case and discuss the various possibilities of why such a problem should arise. The bleeding was secondary to systemic-pulmonary artery shunting, caused at least in part by extensive pleural adhesions. The exact cause of the adhesions was not determined but possibilities include previous infection or trauma. The tumor was successfully removed surgically.

Adolescent↗

Tumoral calcinosis, diaphysitis, and hyperphosphatemia.

Three children with hyperphosphatemic tumoral calcinosis, including 2 siblings, presented with recurrent pain and swelling of the legs. Laboratory tests, radiographs, and biopsy showed reactive new bone formation of unknown etiology in the diaphyses. The authors hypothesize a relationship between tumoral calcinosis, hyperostosis, and hyperphosphatemia and consider possible mechanisms.

Adolescent↗