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Biomedical subjects

C J Mulder

Publications and source records attributed to C J Mulder.

118 records · Page 7Linked to original sources
PubMed1984

Neonatal group B streptococcal meningitis.

Bacteriological and clinical data on 68 children with neonatal group B streptococcal meningitis were analysed as part of a wider study of bacterial meningitis undertaken between 1976 and 1982. Twenty five per cent of patients died and there was no difference in the mortality rate between early and late onset disease. Sixteen per cent of the infants weighed less than 2500 g at birth but in 50% no predisposing aetiological factor was found. Streptococcus agalactiae type III was isolated in 57% of the patients.

Age Factors↗
PubMedDate not supplied

Branhamella catarrhalis septicaemia in a granulocytopenic patient.

A patient with acute leukaemia developed a maxillary sinusitis and septicaemia with Branhamella catarrhalis during the period of bone marrow hypoplasia. One blood culture also grew Staphylococcus aureus. In the same period, the patient developed tender red skin lesions and disseminated intra-vascular coagulation. The patient recovered when therapy with high dosages of amoxicillin was instituted. At the same time, however, the bone marrow recovered.

Adult↗
PubMedDate not supplied

Endosonography of peri-anal and peri-colorectal fistula and/or abscess in Crohn's disease.

Transcolorectal endosonography (ES) was performed in 36 patients with Crohn's disease suspected clinically to have a fistula or abscess. A hypoechoic or anechoic duct-like lesion immediately adjacent to the anorectal lumen compatible with a fistula was found in 32 patients. A communication between the fistulous tract and adjacent structures such as the skin, anal canal, or vagina was detected in all 32 patients. An anechoic cavity adjacent to or communicating with the fistula was visualized in 29 of the 36 patients. A fistula was visualized in the remaining seven patients with no evidence of an abscess. This anechoic cavity compatible with an abscess was surgically confirmed in 14 of 17 patients. We judged the extent and configuration of the abnormalities to be more clearly visualized by ES when results were compared with fistulography in five patients. There were no ES complications, and we conclude that ES is the preferred diagnostic procedure in patients with peri-rectal pathology because of the low risk of bacterial dissemination and low incidence of patient discomfort. Utilizing ES after non-surgical treatment was successful in 19 patients for documentation of the response to therapy.

Abscess↗