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Biomedical subjects

C Irisawa

Publications and source records attributed to C Irisawa.

44 records · Page 3Linked to original sources

[Metastatic tumor of the spermatic cord from renal cell carcinoma].

The patient was a 54-year-old man with a hard nodule (25 x 15 mm) in his left scrotum. His left spermatic vein had been ligated 6 months earlier because of a varicocele. Preoperative diagnosis was left renal tumor with multiple lung metastasis. The intrascrotal nodule was considered to be a metastatic tumor from renal cell carcinoma. Left nephrectomy was performed and the metastatic lesion of spermatic cord was also removed. Pathological examination showed that the left renal tumor was renal cell carcinoma (clear cell type). The spermatic cord nodule was tumor embolus in dilated veins and consisted of the same clear cells as renal cell carcinoma. Judging from these results, in this case renal cell carcinoma retrogradely metastasized through the spermatic vein to the intrascrotal lesion.

Carcinoma, Renal Cell↗

[Metastatic malignant melanoma of the urinary bladder: a case report].

A 77-year-old male was admitted to our department with the chief complaint of positive occult blood in urine on July 30, 1984. Endoscopically, we found a dark red tumor on the left posterior wall of the urinary bladder, which seemed to have coagula covering it. On August 31, transurethral resection of the bladder tumor (TUR-Bt) was performed, and the pathological interpretation was malignant melanoma. Dermatologically and ophthalmologically, we could not found the primary foci. A month later, cystoscopy demonstrated multiple blue black spots consistent with diffuse melanoma of the bladder. On May 7, 1985, he was admitted to our clinic with right hypochondralgia. On physical examination, the liver was palpable with an irregular surface, and the echogram showed multiple metastasis in the liver. TUR-Bt was carried out again, on May 17, 1985. Ultrastructually resected specimens demonstrated a lot of mature melanosomes in the tumor cells. The course of the patient progressively worsened, and he died on May 30, 1985. At autopsy, we found metastases in the central nervous system, bone, genitourinary tract, gastrointestinal tract and other organs. The left eye ball, which had been diagnosed as ophthalmomalacia by glaucoma six years earlier, was filled by a melanoma mass, and it seemed to be the primary foci.

Aged↗

[A study on hemorrhage during and after operation of TURP (transurethral prostatic resection)--effect of morphine or buprenorphine for suppression of postoperative hemorrhage by epidural infusion].

The majority of hemorrhages occurring during open prostatectomy are induced during the steps for removal of adenoma. However, the hemorrhage during transurethral prostatic resection (TURP) usually takes place at its initial stage, and approx. 50% of the amount of the hemorrhage during the operation occurred within 30 minutes after initiating the operation. When the resection of the adenoma advanced near the surgical capsule, the amount of hemorrhage decreased sharply. This was interpreted to indicate that many of the blood vessels are cut at the initial stage of the operation and that the steps for resection are processed at that stage without special attempt to stop the hemorrhage. We have discussed some aspects for improvement of the methodology for the operation of this kind. The postoperative progress of hemorrhage revealed that the operative cases can be classified into three groups; one was the group with smooth hemostasis since immediately after the operation (Type I and II) and the others were the group with satisfactory hemostasis during the operation and yet with resumption of substantial hematuria (Type III and IV) and the group with continued hemorrhage of substantial amount since immediately after the operation (Type V). It was demonstrated that those showing hematuria of more than 2% at 2-4 hours after the operation and 0.5-1.9% at 6-8 hours after the operation can be rated as falling under the latter two groups and that the check at an early stage and early counter-treatment would induce favorable postoperative progress.(ABSTRACT TRUNCATED AT 250 WORDS)

Buprenorphine↗

[Cancer of the bladder in a patient with spinal cord injury].

A case of cancer of urinary bladder in a 39-year-old incomplete C7 paraplegic male is reported. He was injured in 1962, and was admitted to our department in August, 1982 because of macrohematuria. Intravenous pyelography showed dilation of right ureter and pelvis. Cystography revealed filling defect on the right wall of bladder, but vesicoureteral reflux was not seen. Endoscopically, we found the tumor on the right wall, which seemed to invade to the trigone and right ureteral orifice. CT scan and pelvic angiography showed that the tumor extended extramurally of the bladder and metastasized to lymph-nodes. In November, 1982, bilateral ureterocutaneostomy, and 30 days later, total cystectomy were performed. The removed bladder demonstrated transitional cell carcinoma with undifferentiated tumor cells. The patient died of recurrence of the tumor in the small pelvic cavity, 60 days later. Ten cases of bladder cancer in patients with spinal cord injury were collected from Japanese literature including ours, and the importance of periodic cytology, cystoscopy and random biopsy for early diagnosis of bladder cancer on paraplegics were discussed.

Adult↗

Residual stump metastasis from renal cell carcinoma.

A rare case of ureteral stump metastasis 8 years after nephrectomy for renal cell carcinoma is reported. Twenty-six such cases are reviewed and the etiology of such lesions is discussed. Nephroureterectomy for renal cell carcinoma may be indicated when the risk of urogenous implantation and/or hematogenous spread is present.

Carcinoma, Renal Cell↗

[Fracture of the penis: a report of 6 cases and review of 282 cases in Japan].

We have experienced 6 cases of fracture of the penis between 1974 and 1984 at our department. The patients were between 19 and 36 years old. The penis was swollen and distorted by a subcutaneous hematoma but no complications, such as urethral bleeding, pain of miction and urinary retention, were seen in any case. Operation was performed on all patients and no sequelae were seen after treatment. We reviewed 282 cases of fracture of the penis reported in the Japanese literature between 1934 and 1984. A brief review on cause, age, symptoms, complications and sequelae were discussed.

Adult↗

Transferrin concentration in seminal plasma with special reference to serum hormone levels in infertile men.

The concentration of transferrin in seminal plasma and serum levels of LH, FSH, testosterone, and prolactin were measured in 94 male patients attending our infertility clinic. The concentration of transferrin in patients with azoospermia was lowest among azoospermia, oligozoospermia, and normozoospermia groups. There was significant positive correlation between the concentration of transferrin in seminal plasma and sperm density. However, seminal plasma transferrin was inversely correlated with serum levels of LH, FSH, and prolactin, respectively. It is suggested that transferrin in seminal plasma contributes to the activation of seminiferous tubules and can be used as a reliable index of Sertoli cell function.

Adult↗