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Biomedical subjects

C Hoffmann

Publications and source records attributed to C Hoffmann.

At least 127 records · Page 7Linked to original sources

Activation of granular cells during extracorporeal circulation--comparison between bubble-, membrane and hollowfiber oxygenators.

Summarizing our data we can say, that some hematologic disorders during extracorporeal circulation can be diminished by the use of new oxygenator types like the membrane and the Hollowfiber oxygenator. This correlates to the results of other research teams. In contrast to that the activation of the complement cascade is caused by the three systems in a similar way. Although we know, that the activation of the complement systems is only one of numerous reasons for postoperative pulmonary complications, we still must regard this as an important factor, so that the aim of further investigations should be to reduce complement activation during long term ECC.

Adult↗

Doppler-sonographic examination of the arterial flow in the carotid and supratrochlear arteries during carotid angiography.

In 55 patients, the blood flow in the carotid and supratrochlear arteries was examined by Doppler sonography during cerebral angiography. In general, a threefold response was observed: an initial phase of turbulence during the injection was followed by a phase of depressed and then of increased arterial flow. The second phase of reduced perfusion which probably is caused by the increased viscosity of the mixture of contrast medium and blood, is more pronounced in the internal carotid artery, whereas the third phase of accelerated flow is more marked in the external carotid artery. In patients with an occlusion of the internal carotid artery, the cerebral blood supply often depends on the collateral pathway via the ophthalmic artery. In these cases, the reduction of the blood flow is specially marked and long-lasting, as we could show. This may contribute to a higher angiographic risk of those cases with an important ophthalmic collateral flow.

Adolescent↗

[Late extrapyramidal hyperkinesis and neuroleptic withdrawal dyskinesia. Practical problems].

Neuroleptic-induced, late-occurring dyskinesia has gained more and more of importance. Essential causes are: increased continued long-term treatment as well as the advanced age of long-term patients treated with neuroleptics. Problems of daily practice and their treatment find little attention, contrary to the wide-spread literature on theoretical cases and diagnostic criteria of disturbances. Withdrawal- and tardive dyskinesiae are the most important among neuroleptic-induced dyskinesiae. The manifold disturbances of motion are generally found in the orofacial region, the trunk, and the extremities. Errors in differential diagnosis will occur occasionally.

Antipsychotic Agents↗

[Heck's focal epithelial hyperplasia].

Three patients with focal epithelial hyperplasia Heck are presented. In two cases biopsies were made and investigated biochemically and by electron microscopy. In one case typical papillomavirus and HPV 1-DNA could be demonstrated, in the other the attempts of isolation failed. Virologic results and epidemiologic considerations suggest a viral etiology of focal epithelial hyperplasia Heck, but they are not sufficient to prove this.

Adult↗

[Os lunatum partitum].

About two years after a questionable accident which did not lead to disability, the lunate bone was excised. It was found to be in two parts and the question was raised whether or not this was the result of an accident or secondary to Kienböck's disease. The radiologist describes the possible etiologies in his differential diagnoses and concludes that there had been a constitutional Os lunatum partitum.

Adult↗

[Behavior therapeutic training for weight reduction].

A behaviour therapeutic program for weight reduction was worked out by a team of psychologists, dieticians and doctors. A 10 week's course for weight reduction was given by 8 dieticians to a group of 5-7 female overweights (N=50). All dieticians based their work on a written handout. 4 of them had an additional training in behaviour and group therapy prior to the course. During the course all participants showed a significant weight loss and a change in their eating behaviour, the patients counselled by an additionally trained dietician (group E1) showing a significantly greater weight loss than the others (group E2). A follow-up after 3 1/2 months revealed similar differences but subsequent controls after 6 and 20 months showed a gradual decrease of the difference between the two groups. However three different patterns of the patient's weight curve could be distinguished. Pattern a): 26.3% of the participants showed a sinking tendency over all 20 months. Pattern b): 21.4% of the participants showed a significant weight loss over the 20 months with a slight upward tendency after the second follow-up (6 months). Pattern c): 52.3% of the participants lost weight only during the course which was regained in the following 3 months period. In pattern a) and c) group E1 and E2 are evenly represented. Pattern b) was only seen with participants of group E1. The results suggest that there are different characteristics of obese persons which influence the success of weight reduction programs. Further studies will have to describe these characteristics and define their therapeutical implications.

Behavior Therapy↗

Time of natural exfoliation of deciduous teeth.

Over 6000 naturally exfoliated deciduous teeth were sent in to the Department of Preventive Dentistry, University of Sydney over a 10-year period 1964-1974. Adequate histories for 2,828 teeth from 1,558 children were used to determine average ages of children at time of exfoliation of the teeth. Teeth lost at an earlier age were most frequently returned with similar numbers of left and right teeth. There were no differences in exfoliation times for corresponding teeth from left and right sides of arches. Girls had earlier exfoliation times than boys and lower teeth were generally exfoliated prior to upper teeth.

Adolescent↗