Biomedical subjects
Publications and source records attributed to C Hess.
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BACKGROUND: The evaluation of the birth position and its effects on maternal and fetal wellbeing has been a topic of perinatal research over the last decades. The aim of our observational study was to determine the effects of a modified and vertical maternal position on fetal oxygen saturation measured by pulse oximetry. METHODS: Fetal oxygen saturation was measured by pulse oximetry in 56 labouring women randomly and successively adopting the supine position in 96.4%, the sitting position in 25.0%, the standing position in 14.3% and the prone position in 12.5%. The statistical analysis addressed the integrated 10 minutes period of SpO2 registrations before versus after adopting the modified position. Furthermore the mean values and the standard deviation (SD) for the total registration periods of different birth position was calculated. RESULTS: While the supine position induced a reduction in oxygen saturation, sitting and prone position were favorable for fetal oxygenation as compared to horizontal position. DISCUSSION: These findings implicate a clinical benefit of the modified birth position.
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Total and ionized calcium and other related parameters were measured in 34 patients with multiple myeloma. Hypercalcemia was not a major feature of the group of patients studied with only three patients exhibiting marked increases in total (Ca total) and ionized (Ca++) calcium concentrations. The Ca++/Ca total ratio was also maintained within relatively narrow limits. No major differences were found in the calcium fractions of patients with different types of multiple myeloma. Serum immunoreactive parathyroid hormone showed no consistent relationship with either the total or ionized calcium concentration. There were no correlations between increased total protein or reduced serum albumin concentrations and changes in total and ionized calcium fractions or Ca++/Ca total ratios. These results imply that in this group of myeloma patients, there was no significant binding of calcium by the monoclonal immunoglobulins.