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Biomedical subjects

C Green

Publications and source records attributed to C Green.

At least 253 records · Page 14Linked to original sources
PubMed1985

Refining personality assessments by combining MCMI high point profiles and MMPI codes, Part I: MMPI code 28/82.

In this study it has been shown that the addition of MCMI high-point code types to the MMPI 28/82 code type clarifies contradictory MMPI descriptors and locates three distinct clinical clusters. These MMPI/MCMI clusters were defined as an interpersonally acting-in group, an emotionally acting-out group and an emotionally acting-in group to describe the levels on which they characteristically operate. The results of this study lend support to the utility of combining two objective assessment instruments for the purposes of identifying and discriminating subtleties among relevant personality disorders (DSM-III: Axis II) and clinical syndromes (DSM-III: Axis I).

Acting Out↗
PubMed1985

Refining personality assessments by combining MCMI high point profiles and MMPI codes. Part II. MMPI code 27/72.

The relationship between the MMPI 27/72 code type and MCMI high point codes is examined for 228 psychiatric patients. MCMI high point codes that correspond highly with MMPI 27/72 code enable the clinician to identify three discrete personality subgroups entitled: Fearfully Dependent, Conforming-Dependent, and Ambivalently Dependent. The central features of each of these groups are described, and their clinical characteristics used as a basis for differentiating ambiguities and contradictory interpretations commonly given the MMPI 27/72 code type.

Adult↗
PubMed1985

Refining personality assessments by combining MCMI high point profiles and MCMI codes. Part III. MMPI code 24/42.

In this study it has been shown that the addition of MCMI high point code data to the MMPI 24/42 code type serves to clarify contradictory MMPI descriptors and produces three distinct clusters. These MMPI/MCMI clusters comprise an interpersonally acting-out group, an interpersonally acting-in group, and an emotionally acting-out group. These groups were useful in determining different roles for the MMPI 2 and 4 scales insofar as they relate to both personality (Axis II) and its clinical consequences (Axis I). The results of this study also lend support to the utility of combining objective assessment instruments both for identifying and for discriminating among relevant personality disorders and clinical syndromes.

Adult↗
PubMed1984

Lipid organization in erythrocyte membrane microvesicles.

The aminophospholipids of microvesicles released from human erythrocytes on storage or prepared from erythrocyte ghosts by shearing under pressure are susceptible to the action of 2,4,6-trinitrobenzenesulphonic acid. The aminophospholipids of the former vesicles are also susceptible to attack by phospholipase A2. Under the same conditions, the aminophospholipids of erythrocytes undergo little reaction. This suggests that the phospholipids in microvesicle membranes are more randomly distributed than those in erythrocyte membranes. Measurements have also been made of the ability of filipin to react with the cholesterol of sealed and unsealed erythrocyte ghosts and of microvesicles prepared from them. From the initial rates of reaction, it was concluded that there is no preferential transfer of cholesterol molecules from one side of the bilayer to the other during the formation of the microvesicles.

Cholesterol↗
PubMed1984

Lack of evidence for protein AA reactivity in amyloid deposits of lattice corneal dystrophy and amyloid corneal degeneration.

Amyloid fibrils occurring in primary and myeloma-associated (AL), secondary (AA), and certain neuropathic hereditary forms of systemic amyloidosis can be distinguished biochemically or immunohistologically as being composed of immunoglobulin light chain, protein AA, or prealbumin respectively. All types of systemic and several localized forms of amyloidosis contain amyloid P component (protein AP). We studied formalin-fixed tissue from eight cases of lattice corneal dystrophy by the immunoperoxidase method using antisera to proteins AA and AP, to normal serum prealbumin and prealbumin isolated from a case of hereditary amyloidosis, and to light-chain determinants; additional cases were examined by indirect immunofluorescence of fresh-frozen material. We found weak (1:10 dilution) staining with anti-AP, but no reactivity with other antisera. Congo red staining was resistant to pretreatment of sections with potassium permanganate, a characteristic of non-AA amyloid. Two-dimensional gels of solubilized proteins from frozen tissue from two cases of lattice corneal dystrophy resembled those obtained from normal human cornea. Western blots of two cases of polymorphous amyloid degeneration and solubilized protein from normal cornea did not react with radioactive iodine-labeled anti-AA or anti-AP with purified protein AP and unfixed protein AA amyloid tissue as controls. We were unable to corroborate the presence of protein AA in the amyloid deposits of lattice corneal dystrophy. Although staining with antiserum to protein AP was demonstrable, the molecular configuration of this protein in stromal deposits remains to be defined.

Amyloid↗
PubMed1984

Serology and genetics of an MNSs-associated antigen Dantu.

Dantu, a previously undescribed low-incidence red cell antigen, is inherited as a Mendelian dominant character. The Dantu antigen is associated with very weak s antigen, protease resistant N antigen and either very weak or no U antigen. Two of the propositi had previously been shown to have an unusual hybrid MNSs sialoglycoprotein, and it is probably this which carries these unusual N, s and U antigens as well as the Dantu antigen. A study of the family of one propositus suggests, by conventional genetics, that Dantu is not controlled by the MNSs locus; a possible explanation is given. Several examples of anti-Dantu are known, one was found to cause a positive direct antiglobulin reaction on neonatal red cells.

ABO Blood-Group System↗
PubMed1984

The adhesion of different cell types to cultured vascular endothelium: effects of culture density and age.

The adhesion of lymphocytes, macrophages and resuspended smooth muscle cells to freshly subcultured bovine aortic endothelial cells is considerably greater than their adhesion to in-situ aortic endothelium when tested in vitro. Experiments with endothelial monolayers of different cell density and maturity suggest that this can be explained, at least in part, by two factors--firstly, an inverse relationship between macrophage, polymorph and smooth muscle cell (but not lymphocyte) adhesion and endothelial cell density, and secondly, an inverse relationship between endothelial adhesiveness and time since a culture became confluent. These observations may help to clarify the relationship between endothelial adhesiveness in vitro and in vivo, and to explain why leucocytes tend to adhere to regenerating arterial endothelium.

Animals↗