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Biomedical subjects

C Golimbu

Publications and source records attributed to C Golimbu.

At least 55 records · Page 3Linked to original sources

Computerized tomography of pelvic osteomyelitis in patients with spinal cord injuries.

Computerized tomography (CT) was performed in 19 patients with spinal cord injury (SCI) who had large pressure sores and in whom other complications were suspected. CT detected the depth, extent, and degree of undermining of the edges of the pressure sores in 19 of 27 lesions. Conventional radiography detected four cases of pelvic osteomyelitis. CT detected eight additional cases of pelvic osteomyelitis, as well as eight clinically unsuspected peripelvic and intrapelvic abscesses. Technetium-99m bone scanning was not very helpful because of localization in chronic proliferative changes of bone and widespread foci of myositis ossificans, as well as in osteomyelitis. Gallium-67 scanning detected only one of six abscesses. It was not very helpful because of confusion of abscess and osteomyelitis with intense soft tissue swelling and cellulitis, which are often associated with pressure sores in patients with chronic SCI. CT was found to be, by far, the modality of choice for detection of pelvic osteomyelitis and abscess in patients with SCI.

Abscess↗

Pathologic fracture in systemic mastocytosis. Radiographic spectrum and review of the literature.

Systemic mastocytosis is a multiorgan disease that most commonly affects the skin and skeletal system. Radiographically, the skeletal changes in the majority of patients consist of either a wide-spread mixture of bone lysis and osteosclerosis or generalized osteoporosis. The osteoporotic form is less well known but may lead to severe generalized demineralization and pathologic fractures. Mast cells secrete a number of substances, two of which (heparin and prostaglandins) are believed to have a role in the induction of osteoporosis. Sclerotic lesions are induced by another mast cell by-product, histamine. One hundred seventy-eight cases of bony mastocytosis have been reported in the literature, including the four patients in the present report. Special staining procedures are necessary for identification of mast cells. Diagnosis may be delayed in patients who do not have the skin lesions (urticaria pigmentosa) and in the osteoporotic form of the disease.

Adult↗

The impact of CT in clinical management of pelvic and acetabular fractures.

Thirty-eight consecutive patients admitted to the hospital with pelvic and acetabular fractures underwent CT examination. The axial plane of CT is shown to be the most suitable for evaluation of these fractures. The fracture pattern is readily demonstrated, facilitating fracture classification. The degree of fracture fragment displacement and rotation, hip joint stability, and intra-articular osseous fragments can be determined. A number of unsuspected fractures were detected, including five sacral and four anterior acetabular wall fractures; the latter were due to extension of superior ramus fractures. Soft tissue injuries included several hematomas, serosanguinous cysts in one patient, and bladder laceration in one patient. It is concluded that in patients with pelvic fracture CT examination is the method of choice following preliminary radiographic evaluation, if further radiographic investigation is deemed necessary.

Acetabulum↗

Bilateral acetabular stress fractures in a paraplegic patient.

Advances in rehabilitation programs have enabled many paraplegic persons to take part in activities in which the risk of trauma and skeletal injuries is comparable to that in the general population. Stress or spontaneous fractures are known to occur mainly as a result of severe osteoporosis and uncontrollable motion following removal of leg braces. However, stress fractures due to repeated minor trauma or prolonged physical activity have not been previously observed in paraplegic persons. In this report, bilateral acetabular stress fractures are described in a young paraplegic man during the course of ambulation therapy. The pattern of ambulation in these patients, who attempt to walk with crutches while their legs are placed in braces, is one contributing factor to stress fracture. Because of the paucity of physical findings and absence of pain, these fractures may go unrecognized, which can lead to more serious complications.

Acetabulum↗

Computed tomography of pressure sores, pelvic abscess, and osteomyelitis in patients with spinal cord injury.

Nine patients with spinal cord injury (SCI) and large pressure ulcers and other possible complications, were evaluated by computed tomography (CT), conventional radiography, tomography, bone scanning, gallium scanning, and sonography. CT revealed the depth, extent, and relationship of the ulcer-bed to the underlying structures in all 9 patients. CT also positively identified unsuspected intra- and extra-pelvic abscess and pelvic osteomyelitis in 4 patients each. Other modalities identified only 2 of these complications. We believe CT is the modality of choice for evaluation of these complications in SCI patients, because of its superior ability in evaluation of pressure sores and detection of pathologic changes in soft tissue and bone in the pelvic region.

Abscess↗

Hydrometrocolpos and polydactyly.

Two cases of hydrometrocolpos and polydactyly in female infants with persistent urogenital sinus are reported. The importance of considering hydrometrocolpos as the cause of an abdominal mass in female infants with polydactyly is stressed. Cytologic examination of the vaginal fluid may help in early diagnosis.

Abnormalities, Multiple↗

Rupture of a non-rheumatoid popliteal cyst: a syndrome mimicking thrombophlebitis.

Rupture of a popliteal cyst and dissection of its contents into the calf may produce pain, swelling, a positive Homan's sign and other findings closely resembling thrombophlebitis of the calf. The correct diagnosis is not often made, and the patient is subjected to needless long term anticoagulant therapy with its potential complications. To avoid this, it is essential that this possibility be kept in mind in all patients in whom the diagnosis of thrombophlebitis is considered. The history of preexisting arthritis of the knee, joint effusion and popliteal cyst are strongly suggestive of a ruptured popliteal cyst. This diagnosis can be verified by arthrography, ultrasonography, computed tomography and radionuclide scanning. Arthrography is preferred because it reveals superior anatomic detail thereby making differentiation between an encapsulated calf cyst, with smooth walls, and rupture, with irregular feathery margins, possible. Three illustrative cases are presented and the literature is reviewed.

Adult↗

Sacrococcygeal teratoma.

Two cases of sacrococcygeal teratomas are presented. One case illustrates the long course of urologic problems produced by a "successful" removal of the tumor. The literature is reviewed, and the characteristics of this congenital tumor are discussed.

Adolescent↗

Anterior urethral valves.

Three cases of anterior urethral valves, a rare congenital anomaly are reported. Anterior urethral valves probably represent an attempt at duplication of the urethra in the first twelve to fourteen weeks of intrauterine life. The most common type is cusp-like and most frequently located in the bulbar urethra. The presenting complaints are lower tract symptoms, and the diagnosis is usually made by a voiding urethrogram.

Adult↗

Urographic imaging in neonatal period: radionuclide scan and x-ray.

A retrospective study of efficacy of radioisotopic renal scan intravenous urogram in 10 infants with various urologic diseases showed the scan to be more rapid and accurate in depicting the lesions. Since the radioisotopic renal scan requires less irradiation than the intravenous pyelogram, it should be used first as a screening test in infants suspected of having urologic problems.

Contrast Media↗

Pulmonary disorders associated with Sjogren's syndrome.

Pulmonary disorders occur in 25 to 47 per cent of the patients with Sjogren's Syndrome. These are of two types: 1. related to the major connective tissue disorders which commonly accompany this syndrome, and 2. secondary to the peculiar underlying pathology of Sjogren's Syndrome i.e. sicca disorders of the lung. The latter is the more frequent type, occurring mainly in patients with protected sicca complex unaccompanied by a systemic connective tissue disorder, and consists of chronic bronchitis, subsegmental atelectasis, pneumonia, bronchiectasis, lymphoproliferative pulmonary infiltrates and chronic interstitial pneumonitis which may lead to pulmonary fibrosis. 21 cases of Sjogren's Syndrome, 9 of whom had evidence of pulmonary abnormality, are presented, including a case of interstitial pneumonitis leading to diffuse interstitial pulmonary fibrosis. A review of the literature is included.

Adolescent↗

Adventitious hysterogram during intravenous pyelography.

This study reports our experience with uterine opacification noted during infusion urography. The phenomenon is observed in 21.7 per cent of urograms performed on adult females. Examples of this entity are presented and the pathophysiology of the uterine opacification discussed.

Adult↗

Computerized tomography in diagnosis of pelvic abscess in spinal-cord-injured patients.

Twenty-four spinal-cord-injured patients with pressure sores, and suspected of having other complications were studied by CT, gallium scanning, and ultrasonography. CT was found to be by far the modality of choice for evaluation of the extent and depth of the pressure sore, assessment of the thickness of fibrous tissue scar alongside its boundaries and at its base, detection of associated peri-pelvic and intra-pelvic soft tissue abscesses, sinus tracts and osteomyelitis of the pelvic bones.

Abscess↗

Computerized tomography in diagnosis of compression of the common peroneal nerve by ganglion cysts.

A 48-yr old man noted gradual onset of pain, and paresthesia on the lateral aspect of his right leg. The findings were suggestive of S1 root compression. CT of spine was normal. Physical examination revealed a small mass overlying the right fibular head. CT revealed this to be a cystic mass. At surgery a ganglion cyst compressing the common peroneal nerve was found. Peripheral nerves may be compressed by ganglia producing a syndrome mimicking central nerve root compression. CT is the modality of choice for detection of these lesions.

Hip↗

Computerized tomography of the Cupid's bow contour of the lumbar spine.

The inferior endplates of the third, fourth, and fifth lumbar-vertebral bodies frequently have paired parasagittal concavities when viewed in the frontal projection. In the lateral projection, these concavities lie posteriorly and are superimposed. This has been called Cupid's bow contour of the spine. On CT, Cupid's bow is visualized in an axial plane as two rounded relatively well-circumscribed areas of hypodensity rimmed by apparant osteosclerosis in the posterior half of the vertebral bodies. This, on occasion, may resemble metastasis or other pathology of the spine. The CT features, however, once appreciated, are characteristic of this normal variant, helping to distinguish it from other contour deformities of the vertebrae having clinical significance. The CT features are described and the incidence is discussed in 100 patients.

Adolescent↗