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Biomedical subjects

C Giordano

Publications and source records attributed to C Giordano.

At least 217 records · Page 12Linked to original sources
PubMed1977

[Cerebrospinal fluid gamma globulins in neurological disorders affecting black Africans (author's transl)].

Four hundred C.S.F. electrophoreses were carried out in black West Africans (Ivory Coast) suffering from inflammatory disorders of the nervous system. In the normal state, the C.S.F. of the black African contains more gamma globulins than that of the white (15.8% as opposed to 10%). The study provides indirect evidence of the classical notion of the extreme rarity of DS (Disseminated sclerosis) in the tropics. Hypergammaglobulinorachia was demonstrated in 22% of cases, the two principal disorders responsible being trypanosomiasis (57.3%) and sub-acute sclerosing panencephalitis (16.8%). The oligoclonal distribution described in trypanosomiasis was not found. On the contrary, a homogeneous appearance of the gamma zone was constantly demonstrated (49/50). It is possible that these differences are related to the various phases in the course of the disease, and that oligoclonal disturbation is a marker of the auto-immune phase.

Africa, Western↗
PubMed1977

[Inventory of oligoclonal fractions of subacute sclerosing panenephalitis cere-brospinal fluid in Africa with a specific immuneserum: first results (author's transl)].

The oligoclonal gamma-fractions in the cerebrospinal fluid (C.S.F.) from one case of subacute sclerosing panencephalitis (S.S.P.E.) have been studied by means of immunolectrophoresis. The gamma-zone consisted of IgG and free kappa and lambda chains. Besides that, a rabbit immune serum against S.S.P.E. C.S.F. has been prepared. This immune serum did reveal in the gamma-zone one additional protein which is different from IgG and normal tissue proteins. The possibility for this additionnal protein to be of myelinic origin is postulated, because of the demyelinisating nature of the lesion.

Africa↗
PubMed1977

The role of diet in renal disease.

Reutilization of endogenous nitrogen makes it possible to manage many chronic uremics for long periods on diets low in protein without dialysis or transplantation, provided that the protein is of high biologic value and is accompanied by enough calories from nonprotein sources to meet energy needs. But while dietary management of uremia is now feasible, its efficacy is limited by gaps in knowledge about nitrogen metabolism.

Amino Acids, Essential↗
PubMed1976

Actinomyces peritonitis associated with dialysis.

A case of actinomyces peritonitis occurring in a young girl undergoing regular dialytic treatment is reported. The peritoneal localization was the only one detectable and occurred in a patient who at the beginning of the dialytic treatment had received peritoneal dialysis on two occasions. During 4 months of treatment the patient underwent surgical drainage of the peritoneal fluid and medical treatment with various antibiotics. Super-infection with Escherichia coli and Candida, and an acute episode of bronchopneumonia, complicated the course of the treatment which was finally successful

Actinomyces↗
PubMed1975

Ethyl alcohol sniffing by patients undergoing hemodialysis.

Seven uremic patients undergoing long-term hemodialysis became addicted to vapors of denaturated ethyl alcohol. Sniffing produced relaxation, euphoria, and a sense of well-being. In all but one patient, this was the the only form of deviance. Two patients who tried stopping this practice while under psychiatric help were unsuccessful because of acute abstinence symptoms. Denaturated ethyl alcohol does not seem to be toxic per se. In these patients, results of hematological and liver function tests were within normal limits. Anemia supervened in one patient after two years of dialysis, and peripheral neuropathy developed in another.

Acute Disease↗