Search PubMed⌕ Search

Biomedical subjects

C Dupuis

Publications and source records attributed to C Dupuis.

At least 91 records · Page 5Linked to original sources

[Anatomopathology, physiopathology and treatment of the emphysematous disease of infants (apropos of an experience with 133 surgically treated cases)].

Infantile and childhood lobar pulmonary emphysema (LPE) has finally become a rather straightforward problem after 28 years experience and the important statistics published. Contrary to adult emphysema, and leaving aside the particular aspects of causal lesions, the pediatric form is usually a unilateral lobar or infralobar disorder, and therefore lends itself to surgical treatment.

Adolescent↗

[Median- and long-term results of Mustard and Senning operations in isolated transposition of great vessels].

This study concerns 89 cases of isolated transposition with early surgical repair by auricular transposition of the venous returns. Fairly good results were obtained with an operative mortality rate less than 10%, few postoperative complications, and long-term follow-up without significant worsening of the functional capacities of these patients. From this study, the authors state precisely the present indications for treatment of isolated transposition.

Arrhythmias, Cardiac↗

[Coarctation of the aorta and Fallot's tetralogy. Apropos of 2 cases].

Two cases of the association of Fallot's tetralogy and coarctation of the aorta are reported. In both cases there was a right aortic arch. In addition, the second case had a cervical aorta and a left subclavian artery isolated from the aorta and vascularised by the left vertebral artery. The two children underwent complete repair: the first patient had a Waterston shunt followed by repair of the Fallot's tetralogy, followed by repair of the coarctation; the second patient first had a Gore-tex tube inserted from the ascending to the descending aorta and then underwent repair of the Fallot's tetralogy. The association of a coarctation with an obstructive lesion of the right heart is very rare; only two cases have previously been reported: one Fallot's tetralogy and one tricuspid atresia with pulmonary stenosis. Both cases also had a right aortic arch. This seems to go against the haemodynamic theory of coarctation: blood flow in the ascending aorta increases while flow in the pulmonary artery decreases. Coarctation could be caused by a partial involution of the terminal segment of the right primitive dorsal aorta as proposed in cases of coarctation with a right sided aortic arch. The second case also presented two uncommon features: a cervical aortic arch and a left subclavian artery isolated from the aorta.

Aortic Coarctation↗

Heart rate, urinary catecholamines and anxiety responses during mental stress in men in their fifties and seventies.

Alterations with ageing in the responses of heart rate (HR), urinary excretion of free epinephrine (E) and norepinephrine (NE) and anxiety were investigated during mild mental stress. Forty-eight normal male volunteers were studied: in control conditions; when subjected to psychometric tests; and during recovery. Men in their seventies had lower baseline levels of HR, E and NE than men in their fifties. Several anxiety indices were positively correlated with E. HR and NE were positively correlated. During stress, mean HR and E levels increased in the two age groups by the same percentages. Mean HR and E levels returned to pre-stress values more slowly in the older age group.

Age Factors↗

Heart rate reactivity during minor mental stress in men in their 50s and 70s.

Modifications with aging in heart rate reactivity was investigated during minor mental stress. 27 normal male volunteers, aged 51-55 years (n = 10) and 71-74 years (n = 17), were studied in control conditions and while passing a series of 5 psychometric test measuring memory or intellectual speed. Men in their 70s had both lower heart rate baseline levels and lower reactivity during cognitive tasks.

Aged↗

[Atrioventricular discordance without ventriculo-arterial discordance. Apropos of 3 cases].

Three cases of atrioventricular without ventriculo-arterial discordance are reported. The first case was a young woman with situs solitus, atrioventricular discordance and ventriculo-arterial concordance, large atrial and small ventricular septal defects. The functional tolerance was relatively good. The second case was an infant girl with dextrocardia by dextroversion and abdominal situs solitus. The child had atrioventricular discordance with ventriculo-arterial concordance and an ostium primum atrial septal defect. Cyanosis was mild and, in addition, complete heart block was diagnosed on the fourth day of life. The functional tolerance was good in this case too and growth was normal. The third case was a young girl with levocardia, atrial situs inversus, and abdominal situs inversus. A double outlet right ventricle was diagnosed at catheterisation with atrioventricular discordance, ventricular septal defect, and severe valvular and infundibular pulmonary stenosis. The first palliative procedure was performed at eight months: a left Blalock-Taussig anastomosis. As cyanosis has recurred a second procedure is being considered, the child now being 5 years old. Different forms of atrioventricular discordance without ventriculo-arterial discordance have been described: atrioventricular discordance with ventriculo-arterial concordance; atrioventricular discordance with double outlet right ventricle; atrioventricular discordance with double outlet left ventricle; atrioventricular discordance with a single vessel issuing from the right or left ventricle. With reference to their personal cases and those described in the literature, the authors describe the anatomy, physiopathology and the clinical consequences of the different forms encountered in their cases. The different surgical techniques for each anatomical form of this condition are discussed.

Angiocardiography↗

[Assessment of the branches of the pulmonary artery by 2-dimensional echocardiography].

Sixty three cases of Fallot's tetralogy aged from 1 month to 30 years old, were studied by 2D echocardiography to evaluate the diameter of the pulmonary arteries and to detect stenosis of the main pulmonary arteries. The right pulmonary artery was visualised clearly enough to be measured in all 63 cases whereas the left pulmonary artery could only be adequately recorded in 58/63 cases. The junction of the two pulmonary arteries was confirmed by 2D echo in 61/63 cases; in two cases, the left pulmonary artery was not connected (2/63), confirmed at angiography and surgery. Six stenoses of the pulmonary arteries, confirmed surgically (6/7), were detected by 2D echo but there were also 3 false positive results. The pulmonary arteries were measured from suprasternal views; the values obtained ranged from 3 to 15 mm. There was a good correlation with the angiographic measurements (R = 0.81 for the right pulmonary, and R = 0.82 for the left pulmonary arteries). Good correlations were also observed between the peroperative and 2D echo measurements (R = 0.84 for the right pulmonary; R = 0.77 for the left pulmonary artery). 2D echocardiography is a non-invasive reliable technique for visualising the pulmonary arteries and their origin, for measuring the calibre of these vessels and for detecting severe proximal pulmonary artery stenosis.

Adolescent↗

[Left coronary artery arising from the pulmonary artery. Demonstration by 2-dimensional echocardiography].

The authors report the case of a baby in whom an ectopic left coronary artery arising from the pulmonary artery was suspected on clinical and, in particular, electrocardiographic criteria. M mode echocardiography showed left ventricular dilatation with reduced shortening fraction of the LV internal diameter. 2D echocardiography with a mechanical sector scanner demonstrated the left coronary artery arising from the pulmonary artery. The short axis view of the basal vessels in the left parasternal incidence visualised 2 cm of the left coronary artery arising from the posterior part of the pulmonary artery.

Coronary Vessel Anomalies↗

The effects of psychosocial stress on urinary excretion of adrenaline and noradrenaline in 51- to 55- and 71- to 74-year-old men.

The experiments were done to investigate modifications with aging in reactivity and speed of recovery of the sympathetic adrenomedullary system during psychosocial stress. Normal male volunteers were studied. Urinary adrenaline and noradrenaline, diuresis, pH and specific gravity were measured. Adrenaline and noradrenaline baseline levels were lower in the older age group. Adrenaline levels increased by the same percent during stress in the two age groups, but came back to pre-stress values more slowly in older subjects, as did blood pressure.

Age Factors↗