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C Dimopoulos

Publications and source records attributed to C Dimopoulos.

At least 73 records · Page 4Linked to original sources
PubMed1989

[Extracorporeal shockwave lithotripsy: our experience in 5,000 cases].

The authors report their experience on 7,500 patients who underwent extracorporeal shock wave lithotripsy (ESWL1). The first 6,800 were treated with the standard Dornier HM-3 lithotripter, while the remaining 700 were treated with the modified HM-3 machine equipped with the new ellipsoid (and the double-shot generator). The authors present the results and conclusions from their experience with 5,000 ESWL treatments which were performed at their Urology Department. An analysis is made on patient age, sex, stone site, duration of sessions, average number of shock waves used, exposure time, number of electrodes per session, retreatments, and results achieved relative to stone size. Furthermore, the authors report on the complications and treatment in special cases; i. e., patients with horseshoe kidneys, solitary kidneys, spinal cord lesions, radiolucent calculi, hemophilia, and staghorn stones. The mean duration of treatment was 37 minutes. The average number of shock waves used was 1,703. The mean radiation exposure time was 1.9 minutes. Two electrodes per session were required in 48% of the patients. Three months following lithotripsy, 72% of the patients were stone-free, 19% had small remaining stone fragments, and 9% had unimportant stone particles.

Adult↗
PubMed1988

Corynebacterium-induced cystitis with mucosal incrustations.

Alkaline-incrusted cystitis is a rare condition that was first described more than 70 years ago. Since then few cases have been reported. To our knowledge, we report the second such case in the literature in which Corynebacterium D2 was considered as the causative factor of incrusted cystitis.

Adult↗
PubMed1988

Methodology, results and complications in 2000 extracorporeal shock wave lithotripsy procedures.

Since the installation of an extracorporeal shock wave lithotriptor (ESWL) unit 12 months ago, 2000 lithotripsy procedures have been performed. Overall, 68.4% of patients were stone-free by the end of the first month. Residual lithiasis (fragments less than 0.5 cm) was seen in 19.7% of patients and significant lithiasis (fragments greater than 0.5 cm) was observed in 10.1%. Complications were obstruction, infection, headache due to the epidural anaesthesia, anuria, renal failure, perirenal haematoma and cardiac arrest. A number of patients required additional operative treatment; this was always endoscopic and no open procedures were performed. Hospitalisation averaged 1 day.

Female↗
PubMed1988

Common characteristics of primary cell cultures originated from invasive urothelial carcinoma.

Ten primary cultures from invasive urothelial carcinomas were studied by light and electron microscopy. In all cultures, cells with accumulations of glycosaminoglycans were observed. Long membrane extensions with accumulations of glycosaminoglycans invaded neighboring cells and formed an extracellular matrix as well. The extracellular matrix inhibited cell proliferation and enhanced tumor nodule formation.

Aged↗
PubMed1988

Morphological and immunohistochemical characteristics of a cell line originated from noninvasive human bladder transitional-cell carcinoma.

A cell line (IG) was derived from a noninvasive transitional cell carcinoma grade II. The cells were propagated in vitro for 9 months, had a low proliferative capacity, formed tumor nodules, and showed four characteristic morphological stages. Primary epithelial-like cells were characterized as stage I; fibroblast-like cells with loss of contact inhibition of growth as stage II; fibroblast-like cells with long cytoplasmic projections, massive glycosaminoglycan content and tumor nodule formation as stage III; and, as stage IV, granulated stellate cells. The cell culture progressed cytologically from well-differentiated stage I to less-differentiated stage IV. The four stages were confirmed and examined by electron microscopy. Immunoreactivity for fibronectin, keratin, epithelial membrane antigen and carcinoembryonic antigen shown by the cell line and the tissue indicates that the cell line represents the original cell population in the tumor. Glycosaminoglycan production by these cells was found to be responsible for the formation of tumor nodules which appeared in culture at the same time as the patient had developed an invasive bladder tumor. Glycosaminoglycans were observed as a massive accumulation intracellularly and extracellularly, as rods or thick slices in layers of adherent vesicles and granules covering the cell culture. Normal bladder epithelial cells and fibroblasts grew in monolayer, showed contact inhibition of growth, were devoid of intracellularly accumulated glycosaminoglycans and produced uniform extracellular matrix different from that of IG cells.

Adult↗
PubMed1988

Growth characteristics of cultured human normal bladder epithelial cells: a comparison with urothelial carcinoma cell cultures.

We present the in vitro growth characteristics and morphology of the first established long-term culture of human normal bladder epithelium. Normal bladder cells were grown with a mean generation time of 44 h and a life span of 33 population doublings in 12 weeks. The cells exhibited contact inhibition of growth. The cultures were morphologically examined and compared with transitional cell carcinoma in culture.

Adult↗
PubMed1987

The effect of pentosanpolysulphate and carbenoxolone on bacterial adherence to the injured urothelium.

The effect of the glycosaminoglycan (GAG) layer on the adherence of Escherichia coli to the bladder urothelium of rats has been studied. The study was performed by destroying the GAG layer and the changes were observed using the electron microscope. Bacterial adherence to the bladder with a destroyed GAG layer was much higher than to the normal bladder. Following the destruction of the GAG layer, the instillation of sodium pentosanpolysulphate significantly reduced the adhesion of bacteria. Prophylactic intramuscular administration of carbenoxolone increased the speed of regeneration of the destroyed GAG layer.

Animals↗
PubMed1987

The operation of lithotomy in ancient Greece.

Opening the bladder via the perineum in order to remove a bladder stone was practised by the ancient Greek surgeons in very early times, probably from the days of Homer. The technique of lithotomy was described for the first time by Celsus in the first century AD and has come to be known as the lesser operation or 'apparatus parvus', so called because only to instruments are needed for it, a knife and a hook. Two fingers of the surgeon's left hand were introduced into the patient's rectum while an assistant pressed on the lower abdomen to encourage descent of the stone near the neck of the bladder. A slightly curved incision was made in the skin near the anus and a second transverse incision was made through or immediately above the prostate, opening the bladder neck. The calculus was extracted from the wound by the fingers or by a hook. This ancient method of lithotomy as described by Celsus was the only one performed until the middle of the 16th century, and many surgeons advised the apparatus parvus as the operation of choice in young patients until the middle of the 18th century.

Greece, Ancient↗
PubMed1987

Renal hilus lipomatosis simulating carcinoma of the kidney.

We report a case of lipomatosis of the renal hilus which presented with macroscopic painless haematuria. The appearance of the pyelocalyceal system on the intravenous urogram set the diagnosis of renal carcinoma, a diagnosis that both ultrasound and computed tomography did not refute. Final diagnosis was established histologically.

Aged↗
PubMed1986

Human leukocyte antigens and vesicoureteral reflux in Greek children.

Human leukocyte antigens (HLAs) were determined in 43 Greek children suffering from vesicoureteral reflux. Children carrying HLA AW19 + 29 were found to have a higher risk of developing the disease. It is suggested that the HLA system may play a role in the pathogenesis of vesicoureteral reflux.

Adolescent↗
PubMed1986

[Association of a rare form of testicular ectopia, a persistent Müllerian duct syndrome and a supernumerary ectopic epididymis].

We report the first case of persistence of the Müllerian duct associated with transverse testicular ectopia and a supernumerary ectopic epididymis in the same hemiscrotum. The patient is a thirty-year-old man with azoospermia. Uterine and Fallopian tube structures were clearly recognizable within the Müllerian remnants. The ectopic supernumerary epididymis was detected at the lower pole of one of the two testicles and had to be removed surgically.

Adult↗
PubMed1985

Massive incrustation on silicone ureteral stent: a severe complication.

We report the first case of unilateral, upper tract obstruction secondary to incrustation and stone formation on a silicone double-J ureteral stent. We believe that the main cause of this complication was the neurological bladder dysfunction of the patient coupled with urinary tract infection.

Adult↗
PubMed1984

Absorbability of mucosa in total replacement of urinary bladder with jejunum. An experimental study.

The absorption of urine components in jejunum substitute for the urinary bladder was studied experimentally in dogs. For this purpose, determination of the blood urea, creatinine, and electrolyte levels as well as measurements of the radioactivity in blood samples after intravesical instillations of radioactive iodine, were done at various intervals after total replacement of the urinary bladder with jejunum. The absorption was found to decrease greatly in one month and to be negligible one year postoperatively.

Absorption↗