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Biomedical subjects

C Cipolli

Publications and source records attributed to C Cipolli.

42 records · Page 3Linked to original sources
PubMedDate not supplied

The influence of depression on memory and metamemory in the elderly.

This study aimed to assess the relationships among depression level, memory and metamemory scores on a large sample of elderly subjects (139 men and 147 women). Preliminary examination showed that none of the sampled subjects had intellectual impairment (as assessed by means of the Mini-Mental State Examination) or neuropsychiatric symptoms. Each subject was administered the Randt Memory Test (RMT), the Sehulster Memory Scale (SMS) and the Geriatric Depression Scale (GDS). A Multivariate Analysis of Covariance revealed a negative influence of depression on the two RMT measures (Acquisition-Recall: AR; Delayed Memory: DM) and on the three SMS measures (Set1: self-comparison; Set2: memory complaints; Set3: peer comparison), and of age on AR and DM, and Set1 and Set2. A Multivariate Regression Analysis showed that DM scores were positively correlated with Set2 in men and women, and with Set1 in women and Set3 in men, whereas AR scores related to Set2 and Set3 in men and Set1 in women. In addition, depression influenced negatively Set1, Set2 and AR scores in both men and women and DM scores only in men. On the whole, the results suggest that depression, memory and metamemory are rather closely related in non-severely depressed older individuals, albeit with slightly different patterns in men and women, and that some areas of metamemory are congruent with objective functioning regardless of the level of depressive symptoms.

Journal Article↗
PubMedDate not supplied

The validity of informant reports in assessing the severity of dementia: evidence from the CAMDEX interview.

The evaluation of a patient's mental state, overall clinical profile and behavioural disturbance in the process of diagnosing dementia requires at least two sources of information: the patient and the informant. Since the severity of the dementia may interfere with the subjective perception of these disorders, it is important to evaluate the consistency between these two sources of information and the clinical and psychometric evaluation made by the physician. Accordingly, in this study five behavioural areas, derived from the semi-structured interview schedule provided by the Cambridge Examination for Mental Disorders of the Elderly (CAMDEX, i.e., Sleep, Depressed Mood, Everyday Activity, Memory and Global Mental Functioning) have been tested on the patient and his/her informant. Eighty dementia patients (mean age = 74 years) and their informants participated in the study. The dementia group was subdivided into two levels of severity according to DSM-IIIR criteria: 41 with mild dementia and 39 with moderate dementia, respectively, matched for age and schooling. The rating of impairment was found to increase along with the severity of dementia in all the above-mentioned areas, except for sleep. However, the source of information per se significantly influenced the evaluation of memory functioning. Moreover, the significant interaction between the two factors considered indicates that memory functioning is evaluated quite differently by the patients and the informants, as only in the assessment made by the latter group did the impairment increase in parallel with severity of dementia. Finally, whereas none of the subjective measures recorded in the patients were significantly correlated with their test scores, the correlations between the informant memory appraisals and patient test results proved to be significant. The present findings confirm the validity of informant reports in assessing cognitive and memory disorders in early-stage dementia, as well as in distinguishing patients with mild from those with moderate dementia.

Aged↗
PubMedDate not supplied

Validation of the full and short forms of the CAMDEX interview for diagnosing dementia: evidence from a one-year follow-up study.

The sensitivity and specificity of the two forms of the CAMDEX interview for dementia diagnosis were assessed in a 1-year follow-up study. At the beginning of the study, 60 patients (22 males and 38 females) who met DSM-IV criteria for dementia and 60 matched controls (15 males and 45 females), were administered the short form of the CAMDEX (short CAMDEX) 3 months after the full one (full CAMDEX). At the follow-up, all patients were administered both the full and short CAMDEX (again with a 3-month interval), whereas controls were administered either CAMDEX form (in any case, at a 12-month interval from initial testing). Upon initial testing, the sensitivity of the full CAMCOG proved to be significantly higher than that of the short CAMCOG, while the opposite trend was observed for specificity, that is the sensitivity of the full Organicity was lower than that of the short Organicity, with specificity remaining equal in the two forms. Upon follow-up, the specificity and sensitivity levels of the two forms did not significantly differ for the CAMCOG and Organicity indices. Moreover, in detecting mildly demented patients, the full CAMCOG proved to be more accurate than the short one, while the opposite trend was observed for Organicity. Among the dementia subjects, significant correlations were found between the homologous indices of the two forms for both test sessions. On the whole, the short CAMDEX appears to maintain most of the psychometric properties of the full version and therefore the two CAMDEX forms can be considered to be interchangeable.

Aged↗
PubMedDate not supplied

Validation of the full and short forms of the CAMDEX interview for diagnosing dementia. Cambridge Examination for Mental Disorders of the Elderly.

The present study compares the sensitivity and specificity of the short and full forms of the Cambridge Examination for Mental Disorders of the Elderly (CAMDEX) interview in diagnosing dementia. We tested 73 subjects meeting DSM-IIIR criteria for dementia and 61 matched controls. The short version was applied 3 months after the full one to guarantee a relative stability of the tested functions. Referred to an independent clinical rating made at the beginning of the study, the levels of sensitivity and specificity were not significantly different in the two forms and fully comparable with those of the original full English version. Moreover, the scores on analogous sections of the two versions were highly correlated in the demented and control groups. These findings support the hypothesis that the short form of the CAMDEX maintains the psychometric properties of the full one, and consequently can be used in diagnostic routines for a variety of clinical and research purposes.

Dementia↗
PubMedDate not supplied

[Adolescent dyssocial behavior and lack of a father figure during the latency period].

The Authors, taking Andry's hypothesis about the pathogenetic role of the deprivation of father-image during infancy in structuring an inadequate, too rigid or incoherent Super-Ego, assume that could be a possible factor in explaining the social misadaptation of adolescents with prolonged experiences of institutionalisation. The test group, consisted of 163 adolescents and pre-adolescents released from three state institutions in Modena, in the period 1966-1973, it seems to confirm, through the indexes of the socialisation in the family, scholastic and work groups after releases from the institutions, as well as through those of social misadaptation and antisociality, the Author's hypothesis interpreting the social misadaptation as one of the manifestations of the difficulties encountered by adolescents in the adaptation process. These difficulties depend a great deal on a surplus of pathological defenses arising from retarding of the consolidation of the Ego and from developing a negative Ego-Ideal. The deprivation of valid parental images for introjective identifications during latency or adolescence seems a very important factor in influencing these structures of personality.

Adolescent↗