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Biomedical subjects

C Cipolli

Publications and source records attributed to C Cipolli.

At least 37 records · Page 2Linked to original sources

Addiction time and value of Z indicators in Rorschachs of heroin users.

Rorschach test scores for short-term (1 to 3 yr.) and long-term (5 or more yr.) heroin users (ns = 25 each) were compared, to ascertain whether the use of heroin influences the organizational activity, namely, the form level of each response (as measured by Zf and Zd indices). Zd values were significantly lower in long-term than in short-term users, while Zf values approached significance. These findings support the hypothesis that cognitive functioning is impaired along with addiction time.

Adult↗

Vergence movements in comitant strabismus.

Vergence movements induced by base-out prisms were recorded, with an infrared eye tracker, for 6 patients with comitant esotropia (i.e., convergent strabismus) and anomalous retinal correspondence and for 6 normal subjects. Vergence movements of strabismic subjects were much slower and showed characteristics different from those of controls. It may be argued that vergence movements are induced by disparity and represent the motor fusion component left over in strabismus. In fact, in this study accommodative as well as proximal vergence had been ruled out. Therefore, the movements recorded can be considered the objective representation of the well-known phenomenon of prism compensation or adaptation, found in many strabismic patients.

Accommodation, Ocular↗

Methodology of a controlled clinical study for cerebral aging evaluation.

A multicentre study was planned and executed to evaluate the effect of acetyl-L-carnitine in the treatment of cerebral aging. Using 42 health centres, whose comparability of methodology was ensured through a training seminar and an instructional booklet on the psychometric battery of tests employed, some 400 elderly patients aged 60-80 years were enrolled using strict selection criteria. Treatment was run in four phases over 150 days. The first phase, serving as the baseline evaluation, defined through a battery of tests, consisted of 30-day placebo treatment. In the second phase of 45 days, daily treatment with 1500 mg acetyl-L-carnitine was given followed by a psychometric evaluation. For the next 45 days the same drug therapy was employed with a complete psychometric evaluation on the final day. In the last phase of 30 days the placebo was again administered and a final assessment made of the residual benefits of the 90-day treatment with acetyl-L-carnitine. Using this plan made it possible to evaluate the placebo effects, perform cross-study comparisons and demonstrate the effectiveness of the drug treatment.

Acetylcarnitine↗

Recording of disparity vergence in comitant esotropia.

Vergence movements induced by base-out prisms were recorded, with an infrared eye movement recording system, in 5 patients with comitant esotropia and anomalous retinal correspondence and in 5 normal volunteers. The findings support the hypothesis that vergence movements in strabismus are induced by disparity, since accommodative as well as proximal vergence had been ruled out. Vergence movements are much slower and with different characteristics in strabismic patients with respect to normals. It may be argued that vergence movements represent the motor fusion component left over in strabismus. They may be considered the objective representation of the well-known phenomenon of prism compensation or adaptation, found in many strabismic patients.

Adolescent↗

Accessing previous mental sleep experience in REM and NREM sleep.

This study investigated the processes by which contents previously stored in memory are retrieved and inserted into mental sleep experience (MSE). MSE reports were collected from six subjects awakened three times on each of eight nights in two alternate sequences of awakenings (NREM-REM-NREM; REM-REM-REM). The occurrences of interrelations between contents of report pairs were scored using Clark's (1970) feature matching model. These were greater for same night pairs than for different night pairs, and did not differ with respect to sequence of awakenings or order of report pairs (first-second, second-third, first-third). Contents of previous MSEs, therefore, seem to be accessible in both sleep types for insertion into current MSE. The interrelated units were more frequently lexical than propositional, with more paradigmatic than syntagmatic relationships in report pairs from both sequences of awakenings. Thus, the re-elaboration of contents of previous MSEs seems to occur mainly at the level of single contents in both types of sleep, with similar modalities of processing.

Adult↗

Gaze and eye-contact with anorexic adolescents.

Interviews with seven anorexic female adolescents and 12 control subjects were videotaped for analysis of visual behaviour. Individual looking and mutual gaze of subject and interviewer were coded by two judges and recorded through a two-channel push-button system of time recording for 10 min of interview segments. The results indicated that anorexics looked toward the eyes of the interviewer less frequently and more briefly than controls, and that mutual gazing was less common.

Adolescent↗

Interserial and intraserial interference processes in morning recall of mental sleep experience.

This study investigated ways in which predictions from interference theory might explain partial or total failure in the morning recall of mental sleep experience (MSE) episodes reported after provoked night awakening. Interference could take place either between the contents of one MSE episode (intraserial interference) or between the contents of different MSE episodes (interserial interference) and would be more likely to affect morning recall where similar (i.e., interrelated) contents in MSEs are involved. If interference were mainly intraserial, in the morning there would be no change in the difficulty of retrieving interrelated contents, whereas, if it were mainly interserial, there would be increased difficulty in the retrieval of such contents. All the possible pairs of reports obtained by awakening 8 subjects four times in REM sleep during each of four experimental nights spaced at weekly intervals were scored for interrelated contents, using Clark's (1970) system of analysis of paired units, which operates by matching linguistic features. Results showed that interrelations in morning report pairs are as frequent as in night report pairs, maintaining the same linguistic characteristics and with little transfer of contents from one MSE to another. Overall these findings are compatible with the hypothesis that interference is primarily intraserial rather than interserial. It is consequently suggested that morning recall failure may be due to temporary blocking of retrieval.

Adult↗

Role of the central field in disparity-induced vergence movements in strabismus.

Disparity-induced vergence movements (fusional movements) were analyzed in esotropic patients by calculating the time required for compensation of a prismatic correction of their angle of deviation. The effect of central and peripheral field stimulation on these movements was studied by masking the central or the peripheral field. Both the center and the periphery were effective in triggering disparity-induced vergence movements. The center even seemed to prevail over the periphery. It is concluded that in comitant esotropia motor fusion is present not only in the periphery but also in the center, if appropriately tested.

Adolescent↗

The thematic continuity of mental experiences in REM and NREM sleep.

In this study the characteristics of interrelated contents in paired reports of mental sleep experience (MSE) were analyzed to obtain insight as to the functioning of processes by which contents previously stored in memory are retrieved and inserted into MSE in rapid eye movements (REM) and non-REM (NREM) sleep. Ten subjects were awakened 3 times on each of 4 nights after 3 min of NREM sleep (in stage II or III before the first REM), of the first phase of REM sleep, and again of NREM sleep (in stage II or III after the first REM). The contents of all the possible pairings of reports were scored by using Clark's (1970) feature-matching model and compared with respect to the factors 'night' (same/different), 'type of report pairs' (1stNREM-REM/REM-2ndNREM/1stNREM-2ndNREM), 'unit interrelated' (lexical/propositional), 'interrelationship' (paradigmatic/syntagmatic). The occurrences of interrelations were greater for same night pairs than for different night pairs, but without significant differences between types of report pairs: these data provide support for the thematic continuity of MSE in both NREM and REM sleep. The units interrelated in pairs of reports were more frequent at a lexical than a propositional level, showing more paradigmatic than syntagmatic interrelationships: these data suggest that the re-elaboration of contents of previous MSEs occurs mainly at a lower level, and that the modality of processing previous contents by insertion into current MSE is similar in NREM and REM sleep.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

The thematic continuity of mental sleep experience in the same night.

It has been found that the contents of mental sleep experience (MSE) in rapid eye movement (REM) sleep are often interrelated. The aim of this study was to see whether this interrelatedness is better accounted for by the hypothesis that the mental sleep experience interrupted by provoked awakening is resumed when the subject returns to sleep (resumption), or by the hypothesis that the same contents are elaborated repeatedly throughout the night (iterative processing). We also aimed to gain some information as to the processes by which contents previously stored in memory are retrieved and inserted into the current MSE. Ten subjects were awakened 4 times on each of 4 nights after 9 min of REM sleep, and the contents of all the possible pairings of reports were scored and compared with respect to the factors "night" (same/different), "report continguity" (contiguous/noncontinguous reports), "unit interrelated" (lexical/propositional), and "interrelationship" (paradigmatic/syntagmatic). Both the occurrences and the frequencies of interrelations were greater for same night pairs than for different night pairs, but without significant differences between contiguous and noncontiguous pairs: these data provide support for the iterative processing hypothesis. The units interrelated in pairs of reports are more frequently at a lexical than a propositional level and show more paradigmatic than syntagmatic interrelationships: these data suggest that the reelaboration of contents of previous MSEs occurs mainly at a local level, making for the coherence, rather than the thematic, progression of the MSE narrative.

Adult↗

Associative relationships between pre-sleep sentence stimuli and reports of mental sleep experience.

The aim of this experiment was to study some linguistic relationships between pre-sleep verbal stimuli and contents of reports of mental experience during sleep. In 4 weekly sessions 16 subjects listened before sleep to a sentence stimulus, which was either semantically acceptable (SEM+) or not (SEM-), and were told to retain it for a recall test after awakening; they were awakened once each night during NREM or REM sleep and asked to report their mental experience during sleep. The relationships between the stimulus and the contents of the reports were classified using Clark's (1970) associative rules. Both pre-sleep sentence stimuli were frequently incorporated into contents of NREM and REM reports, without significant differences between the two types of sleep. The SEM+ sentence led prevalently to incorporations through paradigmatic associative relationships, while the SEM- sentence led to incorporations through both paradigmatic and syntagmatic relationships. It appears that all the features of the lexical constituents of the stimulus may be involved in the processing leading to incorporation.

Adult↗

Sentence memory and sleep: a pilot study.

In four consecutive weekly sessions 12 subjects, aged 20--25 years, listened to a sentence stimulus before the onset of sleep and were asked to reproduce it after an awakening provoked during stage 2 or REM sleep of the first cycle. Recall of the sentence stimuli heard before sleep was affected by their semantic acceptability, but was unaffected by the sleep type (REM/NREM) or by the length of waking preceding sleep. The differing retention intervals involved for the recall tests after REM and NREM sleep may, however, have masked any effect of the former on recall.

Adult↗

Linguistic organization and cognitive implications of REM and NREM sleep-related reports.

Verbal reports related to REM and NREM sleep were subjected to syntactic (taking Chomskian standard theory as model) and pragmatic analysis (pause distribution within and between kernel sentences). Both in REM and NREM-verbal reports descriptions of the mental experience during sleep were syntactically correct and indicated little difficulty in lexical choice and little emotion. Even though the strategy appears to be the same (sequential) in both cases, the retrieval of content appears to be more difficult after NREM than after REM sleep. Perhaps different degrees of content consolidation in memory occur during the two types of sleep.

Adult↗

Sleep and memory: reproduction of syntactic structures previously evoked within REM sleep-related reports.

7 subjects, aged 19 to 25 yr., who evoked syntactic verbal material in the report made after awakening during REM sleep, were asked to reproduce it a few minutes later. No big differences had been obsered between the two recalls; all recalled verbal materials, many sentences and kernel-sentences reappeared. These results indicate a good consolidation of the material obtained after awakening during REM sleep.

Adult↗

Effect of a memory retrieval task on recall of verbal material obtained after awakening from sleep.

After 66 awakenings from sleep without spontaneous recall of verbal material in the report, the subjects were submitted to a memory retrieval task concerning this kind of material. In 39.3% of the awakenings we found either syntactic, semantic or generic material (the latter never appeared in spontaneous recall); differences are found between fast sleep and slow wave sleep concerning semantic and generic material. The results are discussed in relation to the problem of retrieval and of hypothetical coding and verbal material assessments.

Adult↗