Careers - cardiothoracic nursing: heart and soul.
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Biomedical subjects
Publications and source records attributed to C Campbell.
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This study of an occupationally lead-exposed group in the automobile assembly industry (body shop employees) has provided information with regard to current and recent lead-exposure levels characteristic for these operations. Comparison with findings in other, previously studied occupational groups (secondary smelter workers) indicated that current and recent lead exposure was significantly lower in the autobody shop employees. Prevalence of symptoms was found to be higher than in a control, non-lead-exposed group of maintenance workers in the same plant, but the differences reached the level of statistical significance only sporadically. Long-term effects on renal function, as reflected in blood urea nitrogen (BUN) and creatinine levels, were documented to be significant in this group of autobody shop employees. When compared with two secondary lead smelter populations previously studied, correlations between indicators of renal function, BUN and creatinine, and duration of lead exposure were consistently higher in the secondary lead smelter populations than in the group of autobody shop employees, although duration of lead exposure was greater in the latter. These findings are consistent with a dose-response relationship with regard to renal function impairment due to lead absorption. An increased prevalence of hypertension, especially diastolic, was also found, probably the consequence of renal effect.
The events occurring during the time in hospital of 24 babies were recorded in detail, particularly those related to bowel function. The babies were admitted to a general paediatric unit with various diagnoses a total of 27 times during a six month period. The purpose of the study was to fill gaps in the records of a previous study (Scott et al. 1979) and to try to relate excretion of viruses detectable by electron microscopy to disturbances of bowel function (diarrhoea and/or vomiting). The results showed that a variety of viruses were associated with gastroenteropathy, that virus excretion could occur without disease and that hospital acquisition of virus is not uncommon. Antiobiotic treatment did not appear to precipitate diarrhoea in this small number of babies.
The activity of glutathione peroxidase (GSH-Px) was measured in the erythrocytes of 600 Thoroughbred horses in training; the selenium concentrations in whole blood and serum was measured in over 80 of these Thoroughbreds. A quadratic relationship was demonstrated between erythrocyte GSH-Px and whole blood or serum selenium concentration. There was no significant difference in the activity of aspartate aminotransferase, creatine kinase, or gamma-glutamyl transferase in the serum of Thoroughbreds with high erythrocyte GSH-Px activity (more than 25 u/ml) when compared with those with low erythrocyte GSH-Px activity (less than 15 u/ml).
The purpose of this study was to examine the association of circulating viral markers with ongoing liver disease in chronic hepatitis B virus infection. Hepatitis B e antigen (HBeAg) was significantly more likely to be associated with abnormal alanine aminotransferase (ALT) activity than was anti-HBe in a group of 102 HBsAg carriers (p less than 0.0001). Within this group, 57 carriers were analyzed for HBeAg, DNA polymerase, and hepatitis B surface antigen (HBsAg) titer, and the relation of each with abnormal ALT was determined. Both HBeAg and elevated DNA polymerase were much more likely to reflect abnormal ALT (p less than 0.00001 and 0.0006, respectively) than did HBsAg titer. Unlike previous studies, higher titers of HBsAg would not be demonstrated in healthy carriers when compared to HBsAg carriers with chronic elevation of ALT; nor were differences in titer appreciated between chronic active and chronic persistent hepatitis. The potential significance of these findings is discussed.
A study was carried out to define nutritional problems of women attending family planning clinics (FPCs). Methods of nutritional assessment were chosen to examine relationships between diet and biochemical measures of folacin, riboflavin, and vitamin A status. Findings showed that in the sample of 219 FPC women, 30 percent were obese, 75 percent were low or deficient in plasma folacin, 58 percent were low or deficient in erythrocyte folacin, and 39 percent were low or deficient in riboflavin status (by erythrocyte glutathione reductase assay). Monotonous diets, low plasma folacin, and obesity were characteristic of less well-educated women. Women on contraceptive steroids had slightly lower red blood cell folacin. Riboflavin status was not related to intake of contraceptive steroids but was related to ethnicity.
Diet diversity indexes were examined as examples of qualitative diet indexes. Diet indexes were calculated from food frequency information grouped according to three food taxonomies or left uncategorized. Two diet indexes linked more closely in their construct to measures of nutrient intake were calculated for comparison purposes. The indexes were assessed on the basis of concordance with biochemical measures of vitamin nutriture, simplicity of calculation, and cultural and nutritional logic. The value of the diet indexes lay in their ability to describe, not to assess, food patterns.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.