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Biomedical subjects

C Brocheriou

Publications and source records attributed to C Brocheriou.

At least 127 records · Page 7Linked to original sources

[2 cases of alveolar sarcoma. Study by electron microscopy and cytoenzymology].

Study by electron microscopy and light cytoenzymology of two cases of alveolar sarcoma of the thigh occurring in young men indicated it to be an active tumour with an apparently functional organoid arrangement, characterised by an abundance of capillary vessels. The secretory nature of the cell elements was suggested by the marked development of smooth and granular reticular systems. The morphological result of this secretory activity was constituted by vesicular bodies with dense contents, surrounded by a membrane and sometimes containing periodic paracrystalline structures. This intravacuolar crystalline organisation goes hand in hand with an increase in acid phosphatase activity suggesting possible crinophagia. Amongst the different hypotheses advanced in the past, the morphological appearances seen here would most likely correspond with the endocrine nature of this tumour.

Adult↗

[Recurrent ventricular tachycardia and parchment right ventricle in the adult. Anatomical and clinical report of 2 cases].

Two patients, aged 52 and 55 years, were admitted to hospital for attacks of recurrent ventricular tachycardia for which preventive treatment was difficult. The crises were of one type, with left-sided delay. The findings on clinical examination, electrocardiography, haemodynamic and arteriographic investigation and at post-mortem were those of the parchment right ventricle syndrome of the adult. Electrophysiological investigation in the 2 cases indicated that a re-entry mechanism underlay the attacks of tachycardia. Late activation of the pulmonary infundibulum was responsible for a post-excitation potential on the surface and intra-cavitary leads. Mapping carried out during ventricular tachycardia in one case demonstrated the pathway for re-entry at the level of the pulmonary infundibulum.

Electrophysiology↗

[Primary malignant melanoma of the parotid. One case (author's transl)].

The authors report a case of malignant melanoma of the parotid occurring in a 22-year-old man, followed by two local recurrences after surgical excision, radiotherapy and chemotherapy. The primary parotid nature of the tumour was confirmed by the absence of tumour in other sites and by the histological characteristics.

Adult↗

[Mandibular localization of thesaurismosis (polyvinyl-pyrrolidine) (author's transl)].

The authors report on a case of isolated mandibular localization of polyvinyl-pyrrolidine thesaurismosis. The patient, a man of 38, had been treated with injections of posterior pituitary extract, for a period of eighteen months, 10 year ago. Localization in the mandible is extremely rare, making diagnosis difficult unless a detailed anamnesis is available.

Adult↗

[Inflammatory granuloma of the face with a malignant course. Atypical Hodgkin's disease (author's transl)].

A case of Hodgkin's disease beginning in the skin of the face with local lymph node involvement is reported. This was a lymphogranulomatous form without characteristic Reed-Sternberg cells in skin biopsy specimens, rendering the diagnosis difficult. There was a combination of granulomatous inflammation, plaques of necrosis and lesions of fibrinoid necrosis in the vessel walls. This form entered the classification of clinical Stage IV, with its associated serious prognosis.

Adult↗

Induction in rats of paranasal sinus carcinomas with radioactive cerium chloride.

A colloidal suspension of radioactive cerium stabilized in the form of hydroxide was inoculated into young Sprague-Dawley rats near the maxillary sinus. Well-differentiated epidermoid carcinomas of the paranasal sinus were obtained in 8 of 12 rats and in 8 of 9 animals that liver more then 200 days. Therefore, this istope was highly effectivein inducing tumors at the site of injection. The uniformity of the histologic type of tumors induced under these experimental conditions was remarkable.

Animals↗

Sarcoma arising in irradiated jawbones. Possible relationship with previous non-malignant bone lesions. Report of 6 cases and review of the literature.

Thirty-seven cases of radiation-induced sarcoma of the jaw are reviewed from the literature and six new cases are reported. It appears that irradiation seems to play a significant role in the development of jaw sarcoma: 10% of jaw sarcomas arise in irradiated bone. The initial lesion, however, that required irradiation appears to be equally important: 46% of the cases were found to have fibrous dysplasia as the initial lesion, whereas 18% of the remaining cases included diverse bone lesions. The bone was assumed to be normal in only 36% of the cases where irradiation was administered to adjacent tissue lesions. It seems that the association between irradiation and a pre-existing bone lesion has a definite oncologic effect.

Adolescent↗

[Inclusions of salivary gland tissue in the mandible, various locations, pathogenesis].

In connection with three cases of their own, the authors recall the radiological signs of this entity isolated by Stafne in 1942. They demonstrate that this picture of the mandibular angle or of the premolar area is quite characteristic and suggestive and usually makes diagnosis possible. They show that the inclusion is always of normal salivary glands corresponding to the gland opposite the cavity: sub-maxillary for the angle, sublingual for the premolar area. They prefer the pathogenetic theory that it is an error in development during embryogenesis of the pelvi-lingual sulcus and of sub-maxillary and sublingual gland formation.

Adult↗

Simultaneous allotransplantation of kidney and spleen in dogs with or without previous splenectomy.

29 simultaneous kidney and spleen transplantations have been performed on dogs. Time of rejection, similar for both organs, occurs in a delay very close to the control series. No statistically difference of the day of rejection was observed in relation with the implantation of the spleen either on the iliac or on the mesenteric vessels. Splenectomy few weeks prior to transplantation had no effect on the day and the histological type of rejection of both transplanted organs.

Animals↗

[Suppurative parietal endocarditides].

As opposed to acute or subacute orificial localizations, suppurative parietal endocarditis is a very rare entity (5 cases in 3,900 autopsies). More readily localized in the left heart and being generators of systemic emboli, they remain latent until anatomically verified. Two circumstances promote their occurrence : the focal point caused by the mural thrombus of a recent myocardial infarction ; septicemic infections with pulmonary localization and neighbouring thrombophlebitis within the context of intense depression of immunity.

Adolescent↗

[Temporomandibular menisci].

The temporo-mandibular meniscus is an anatomical structure which has been the subject of very little recent research. The usual macroscopic and dynamic tests were actually carried out on anatomical specimens taken from injected corpses whose anatomical structures were discoloured, stiff, hardened and unrecognizable, or from meniscectomy for pathological meniscus. In order to approximate as nearly as possible to the actual conditions under which anatomical testing is carried out, we dissected and removed 50 temporo-mandibular meniscuses from fresh corpses (14 females, 11 males between the ages of 42 and 78). Here are the partial conclusions from the macroscopic, microscopic and mechanical study of these 50 meniscuses caried out by us.

Adult↗

[Osseous desmoid fibroma of the mandible, a propos of 1 case].

Osseous desmoid fibromas, analagous with soft tissue desmoid fibromas, are rare tumors with exceptional localization in the mandible, revealed by: -tumefaction and trismus in usually very young subjects; -the radiological picture is that of lysis with relatively well defined limits, but with no double outline, with possible cortical rupture and aberrant lacunae far from the main focus which explains possible recurrences of this tumor which is nevertheless benign. The main histological danger is confusion with a differenciated fibrosarcoma. Mandibular resection which is frequently necessary should ensure stable recovery.

Adult↗

[Calcifying odontogenic cyst: apropos of 5 cases].

With reference to 5 personal cases involving the mandible 3 times and the lower gum twice, the authors recall the principal characteristics of calcified odontogenic cysts: very little clinical manifestation frequently limited to simple tumefaction, well bounded radiological image with low density, cyst with an epithelial border comprized of calcification and ghost cells. Calcified odontogenic cysts which have a definite morphological likeness to Malherbe's epithelioma, also have the same benigh course as the latter.

Adolescent↗