[Malignant lymphoma with cutaneous lymphomatoid papulosis lesions].
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Biomedical subjects
Publications and source records attributed to C Brocheriou.
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The authors report on a 76-year-old woman presenting with malignant thymoma associated with myasthenia, erythroblastopenia, myositis and giant cell myocarditis. Blood examination showed antinuclear antibodies, anti-platelet antibodies and LE cells. Only one similar case and 22 cases of thymoma associated with giant cell myocarditis have been published. It seems probable that thymomas plays a part in the pathogenesis of giant cell myocarditis.
Histo-enzymological and ultrastructural studies in 6 cases of cystadenolymphoma were able to confirm the marked metabolic activity of the oncocytic cells, which from the major part of these tumours. The oncocytes demonstrate greatly enhanced enzymatic activity, particularly of those enzymes concerned with oxydative metabolism and the diaphorases. Electron microscopy of the oncocytes shows that they are filled with mitochondria of very varied size and form, sometimes associated with the presence of several intracytoplasmic crystalloids. The second, lymphoplasmocytic component of these tumours present no particular morphological features.
Parotidectomy with conservation of the facial nerve, followed by radiotherapy to lymph glands, was employed to treat a benign lympho-epithelial lesion in the parotid. Clinical characteristics, therapy, and prognosis of this rare affection are described though diagnosis is difficult, the presence of such a lesion should be considered in all cases of parotid tumours.
Four cases of solitary maxillary cysts are reported, and our current knowledge of these rare lesions reviewed. Their diagnosis should be suspected whenever bone lacunae are detected, that are not the result of dental disorders. Surgical exploration demonstrates the presence of a cavity that is almost always unilocular, and contains blood-stained fluid, or is completely empty in some cases. Curettage may be employed but filling by a bone graft is not necessary. No recurrence occurs, in contrast to those present in the long bones, and bone repair is rapid after curettage. Though of a probable dystrophic nature, their true significance is still unknown.
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296 intraoral minor salivary gland tumors were observed among 702 salivary tumors. The study emphasizes a frequent palatine location, observed in more than 50 per cent of theses tumors. Pleiomorphic adenomas (or so called mixed tumors), are frequently encountered; but it is noteworthy that the proportion of muco-epidermoid tumors or adenoid cystic carcinoma is higher among theses tumors than among major salivary glands; this fact explain a poor overall prognosis of minor salivary gland tumors.
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A case of mandibular ameloblastic odontosarcoma in the rat is reported. This tumor was radio-induced by the local injection of radioactive cerium chloride and had a double ameloblastic and fibrosarcomatous tumour component associated with varying degrees of mineralisation of the dental tissues, enamel, dentine and osteocement. This case is compared with the several human and animal cases reported in the literature. However, the problem of the development of a fibrosarcoma within a pre-existent odontoma remains, even though in the case reported here the ameloblastic epithelial structures appeared to be highly abnormal and neoplastic.
The authors present an observation of epithelial tumor with double composent glandular and epidermoid. The true name is adenosquamous carcinoma. Here, it's a case of parotid Tumor. This tumor is very exceptional and very severe.
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The authors review the studies describing dental changes after radiotherapy or curietherapy of the cervicofacial region published over the last 50 years. They discuss more particularly: --direct and indirect effects on the teeth,--lesions of the salivary glands,--dental lesions,--fluoride prophylaxis for dental lesions after irradiation.
The authors report a case of necrotic metaplasia of the salivary glands and review the principal clinical, histological, and evolutional characteristics of this rare affection of unknown etiology. The lesion occurs in adults, is located exclusively in the palate and appears as a small usually greatly ulcerated swelling which is sometimes preceded by pain. Histological examination, which requires a relatively deep and fairly large sample, demonstrates a group of modifications essential for diagnosis: ulceration on a inflammatory base with hyperplasic epithelial borders, plus deeper accessory salivary lobules with necrotic plaques and a great deal of malpighian metaplasia, and conservation of normal gland structure. This affection, which is sometimes wrongly diagnosted as a tumor, heals spontaneously within several weeks, which contra-indicates any strong therapeutic measures.
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