Search PubMed⌕ Search

Biomedical subjects

C Bogdan

Publications and source records attributed to C Bogdan.

At least 109 records · Page 6Linked to original sources
PubMedDate not supplied

A case of aortic valve disease associated with Tropheryma whippelii infection in the absence of other signs of Whipple's disease.

A case of endocarditis caused by Tropheryma whippelii is reported. The 69-year-old patient was diagnosed as suffering from severe aortic regurgitation requiring aortic valve replacement, but showed no other symptoms of Whipple's disease. T. whippelii was detected in the explanted aortic valve by broad-range PCR amplification of the 16S rDNA and subsequent sequence analysis of the product. The etiologic agent was classified as a type 2A sequence variant based on the 16S-23S intergenic spacer and the 23S rDNA (domain III) sequences. The histological examination of the aortic valve was compatible with Whipple's disease. A duodenal biopsy revealed an infection with Giardia lamblia, but T. whippelii and histological signs of Whipple's disease were not detectable.

Actinobacteria↗
PubMedDate not supplied

[Leishmaniasis with cutaneous and visceral involvement in a 13-month old boy].

Leishmaniasis is an anthropozoonosis caused by infection with leishmania parasites with either cutaneous, mucosal or visceral (kala-azar) involvement. While the benign cutaneous form is self-limited death occurs in approximately 80% of children with kala-azar when untreated. The diagnosis of kala-azar should not be missed in children presenting with fever, hepatosplenomegaly and pancytopenia especially with a history of sand fly bites. We report the case of a 13-month-old boy with both cutaneous and visceral involvement.

Animals↗
PubMedDate not supplied

Circadian and circannual variations of FSH, LH, testosterone, dehydroepiandrosterone-sulfate (DHEA-S) and 17-hydroxy progesterone (17 OH-Prog) in elderly men and women.

A group of 63 men and 86 women 77 +/- 8 years of age institutionalized at the Berceni Clinical Hospital, Bucharest, Romania, on a diurnally active living schedule with rest at night, eating 3 comparable but not identical meals a day, were investigated over a 2-year span in 278 profiles extending over a 24-hour span each and distributed over all our seasons. On each day of sampling six samples of blood were collected at 4-hour intervals beginning at 0800 of the first day of the study to 0400 of the next. Plasma testosterone, dehydroepiandrosteronesulfate (DHEA-S), 17-hydroxyprogesterone (17-OH Prog), FSH and LH concentrations were determined by radioimmunoassay. Statistically significant circadian rhythms were detected and quantified by population mean cosinor for the men and women of the entire group and for the age groups of 51 to 70 (I), 71 to 80 (II) and above 80 years of age (III) separately. Circannual rhythms of the circadian means were sought and evaluated by one way analysis of variance. Statistically highly significant circadian rhythms were found in plasma testosterone, 17-OH Prog and DHEA-S, concentrations in men and women of all three age groups with a phase advance of over 2 hours in DHEA-S with advancing age. Circannual cycles were found for plasma testosterone concentration and for DHEA-S in men and women, with a likely phase difference between men and women in testosterone. In LH a circadian rhythm was found in the women and in FSH in men only and a circannual variation in LH only in men.

17-alpha-Hydroxyprogesterone↗