Search PubMed⌕ Search

Biomedical subjects

C Beylot

Publications and source records attributed to C Beylot.

At least 217 records · Page 12Linked to original sources
PubMedDate not supplied

[Peripheral facial paralysis and HIV infection. 2 case reports].

Two cases of peripheral facial paralysis in subjects with HIV infection are reported. On the basis of these two cases and data from the literature, the clinical and paraclinical features of this facial nerve lesion are described. The various aetiological hypotheses put forward are discussed, but it is probable that the paralysis results from a direct effect of the virus on the nerve. HIV-associated peripheral facial paralysis may occur irrespective of the number of CD4 lymphocytes and does not seem to have a prognostic significance. However, it appears by preference in stages I, II and III and may then reveal the HIV infection.

Adrenal Cortex Hormones↗
PubMedDate not supplied

[Leukocytoclastic vasculitis and malignant hematologic diseases. (12 cases)].

We report 12 cases of leucocytoclastic vasculities associated with myelocytic (7 cases) or lymphocytic (5 cases) blood diseases. The clinical features, laboratory abnormalities and pathological findings are presented. In all cases a drug-induced and/or infective origin could be ruled out, and patients with cryoglobulinaemia were excluded. As in other cases found in the literature, in some patients vasculitis was present several weeks or months before the blood disease was discovered, while in others both conditions developed simultaneously or vasculitis appeared in the course of the blood disease. None of these three possibilities seemed to make the prognosis worse. The pathogenesis of the vasculitis-malignant blood disease association is uncertain. Immune complexes of tumoral origin undoubtedly have some responsibility, but some deficiency of phagocytic cells or chemotactic factors also play a role. Cases such as ours enable the significance of vasculitis to be understood when it occurs in a patient with malignant blood disease, but above all they should prompt investigations for malignant blood disease in patients with cutaneous and/or systemic vasculitis, as is being done in patients with pyoderma gangrenosum or Sweet's syndrome.

Adult↗
PubMedDate not supplied

[Cutaneous T-cell lymphoma bullosa: 2 cases].

INTRODUCTION: Since the first case described by Kaposi in 1887, bullous forms of cutaneous T-cell lymphomas are extremely. CASE-REPORT: We describe an unusual case of mycosis fungoides bullosa with palmoplantar dyshidrosis-like eruption and, to our knowledge, the first case of pleomorphic cutaneous T-cell lymphoma bullosa. DISCUSSION: Cutaneous T-cell lymphoma bullosa can be very misleading, particularly when the bullous lesions are inaugural. Differential diagnosis have to be excluded (autoimmune blistering diseases or contact dermatitis during topical treatment of lymphoma or bacterial or viral cutaneous infections) by biopsy, direct immunofluorescence and bacteriological examinations. In these cutaneous lymphoma bullosa, the blisters appear to de due to excessive epidermotropism and/or toxicity of the tumoral infiltrate.

Aged↗
PubMedDate not supplied

[Lymphatoid papulosis. Ultrastructural study. Review of the literature].

The authors report a case of lymphomatoid papulosis with an ultrastructural study, and review 84 cases which they found in the literature. They recall the clinical and histological signs and the course of this disease which usually has a benign prognosis. The classification and relationship with varioliform parapsoriasis of Mucha-Habermann and the hematodermias remain debated.

Aged↗
PubMedDate not supplied

[Renal lesions in progressive systemic sclerosis. A report on five cases (author's transl)].

Renal lesions are one of the must serious visceral complications of progressive systemic sclerosis: three of the five cases reported died in anuria within a few weeks. A part from this very severe fulminating form, however, cases in which lesions can be demonstrated by pathological examination may produce much milder clinical and biological signs, though still having the same prognostic significance. They can become worse at any moment, either spontaneously, or more often because of other factors such as corticotherapy or pregnancy. A review of the published literature has shown the exact frequency of these lesions and their two principal modes of progression, in both of which the same basic histological changes of proliferation of the intima of the interlobular and preglomerular arteries are found. Kidney function tests can be used to guage the severity and extent of these vascular lesions. It is much more difficult, however, to determine the nature of the initial mechanism causing these lesions. The vascular lesion could be a primary one or may be secondary to an immunological disorder, the exact nature of which has still to be determined.

Acute Kidney Injury↗
PubMedDate not supplied

[Trigeminal sensory neuropathy and Sharp's syndrome (author's transl)].

Neurological manifestations are rarely observed with mixed connective tissue disease (MCTD). The most frequent is a trigeminal sensory neuropathy which sometimes appeared as an early symptom. We report a new case of bilateral isolated trigeminal sensory neuropathy during M.C.T.D. Similitudes can be drawn with trigeminal neuropathies observed in connective tissue diseases such as scléroderma. Mechanisms are discussed.

Female↗
PubMedDate not supplied

[The association tretinoin-erythromycin base: a new topical treatment for acne. Results of a multicentric trial on 347 cases (authors transl)].

A multicentric trial involving ten dermatological departments was conducted to evaluate the efficacy and tollerance of ANTIBIO-ABEREL (an association of Tretinoin and Erythromycin base) in 347 patients with persistant acne. Complete healing or considerable improvement was obtained in 85% of cases. This new treatment was active against both inflammatory lesions (papules and pustules) and retentional elements (microcysts and open comedones). It was also rapidly active, as very favorable results were obtained in ten weeks or less, in more than half of the cases. The tolerance was remarkable (less than 1% of cases had to interrupt treatment). This product represents an important progress as compared to Tretinoin alone. No other local or systemic therapy, especially long term antibiotherapy, is required.

Acne Vulgaris↗
PubMedDate not supplied

[Cutaneous manifestation of pheochromocytoma. Report of a case (author's transl)].

A 33 years old woman was investigated for paroxystic hypertension worsened by bêta-adrenergic blocking drugs therapy. Clinical investigation revealed cutaneous abnormalities with erythemato-macular eruption on dorsalis faces of both hands. These lesions were histologically non specific with capillaritis and oedema. angiography revealed a left sided pheochromocytoma. Cutaneous abnormalities disappear after intervention. Pheochromocytoma is rarely associated with cutaneous disease: most papers describe intermittent "flush" phenomenon. Permanent lesions are non fréquent: erythrocyanosis, rash with nodosities or macular lesions, restricted places of necorsis, distal necorsis, hypochromic lesions. The variability of cutaneous disease of pheochromocytoma seems reliable to the biochemical structure of catecholamine secreted by tumor.

Adrenal Gland Neoplasms↗
PubMedDate not supplied

[Frontiers of the histopathologic diagnosis of pigmentary nevus/malignant melanoma in children. Apropos of 5 cases].

The authors report 5 observations of melanocytic nevus (MN) in children, representing a stereotyped "entity" both clinically and histologically. They are characterized by their dark colour and their rapid extension, resembling a beginning malignant melanoma "in situ" Histologically, these MN present a particular "aggressiveness" for the whole epidermis, with large nests of fusiform, regular and pigmented cells. These observations are discussed in regard to the juvenile malignant melanoma, the dysplastic nevus syndrome, the pigmented spindle-cell nevus, the Spitz nevus and overall the "solitary active junctional nevus" of the child.

Child↗
PubMedDate not supplied

[Acute generalized exanthematic pustuloses (four cases) (author's transl)].

Acute generalized exanthematic pustuloses supervening without a genetic psoriatic predisposition are not exceptional if the literature over the last few years is taken into account. Such observations are published under a wide range of names. Beside exanthematic pustular psoriasis as defined by Baker and Ryan, there exists in fact a whole scale of amicrobial pustulosis: acute generalized pustular bacterid; acute generalized pustulosis manifestation of leukocytoclastic vasculitis; pustular necroziting angeitis; pustular eruption with eosinophilic abscesses; generalized pustular drug rash; subcorneal pustules in erythema multiforme and in Sweet's syndrome. Thus, it appears that pustuloses exist in many forms, although they have certain common points that justify a synthetic perspective:--their occurrence, after a bout of infection and/or after taking drugs in subjects with no previous known psoriasis;--a single outbreak occurring spontaneously or with corticoid therapy and which heals by itself;--the existence of a marked vasculitis which occurs before the epidermal pustules. Sometimes this takes the form of a leucocytoclastic vasculitis or a polymorphic infiltrate which is rich in intact eosinophils. Direct immunofluorescence shows deposits of C3 and occasionally IgM at the vascular wall. The circulating antibody-antigen complex produced by an infection and/or by a drug may be responsible of the pustulosis by a hypersensibility mechanism (type Arthus phenomen). From the existing literature and the personal observations of four cases, the authors have made a general review of these pustuloses. They believe that in the majority of cases, pustulosis should not be considered as being psoriatic. However, the authors discuss the rare but possible occurrence of such a pustulosis in patients with a genetic psoriatic predisposition. They feel it would be preferable to avoid the publication of observations under a too wide a range of names, and propose the common heading of "acute generalized exanthematic pustulosis".

Acute Disease↗