Search PubMed⌕ Search

Biomedical subjects

C B Rodning

Publications and source records attributed to C B Rodning.

At least 37 records · Page 2Linked to original sources

Intraluminal measurement of distance in the colorectal region employing rigid and flexible endoscopes.

Intraluminal measurements of distance cephalad to the anal verge in the colorectal region of 40 consecutive adult patients were performed employing rigid and flexible proctosigmoidoscopic techniques. In 2/40 (5%) patients, the measurements were identical. In 32/40 (80%) patients, measurements employing a flexible proctosigmoidoscope exceeded measurements employing a rigid instrument by at least 3 cm. The observations have relevance in the context of assessments of adequate distal margins and preservation of anal continence in patients requiring colorectal surgery via transabdominal, transsacral, transperineal, and/or transanal routes.

Colon↗

A retrospective analysis of inferior vena caval filtration for prevention of pulmonary embolization.

Inferior vena caval (IVC) filtration employing transvenous devices represents a substantive technologic advance in the management of patients with deep venous phlebothrombosis and pulmonary embolization. The retrospective analysis reported herein of the use of the Kim-Ray Greenfield IVC filter in 22 patients revealed a 95 per cent efficacy in its prevention of pulmonary embolization. The minor acute morbidity (9%) and chronic morbidity (27%) associated with use of the device was well tolerated by this patient population. No mortality attributable to the device was observed. The data suggest that the use of this device represented the best therapeutic option among those patients who were not candidates (18/22) or who had failed alternative therapeutic modalities (1/22) for the treatment of deep venous phlebothrombosis or pulmonary embolization. The data also suggest that use of the device in a prophylactic context (3/22) among those patients deemed at "high risk" for the development of deep venous phlebothrombosis and pulmonary embolization may be beneficial.

Adult↗

Component quantitation of rat ileum.

Precise and accurate light microscopic morphometric analyses of biological tissue can be achieved utilizing component quantitative techniques. Component quantitation refers to measurements of the relative volumes of components in tissue sections. Such an assessment is predicated upon the mathematically verifiable assumption that direct quantitative relationships exist between an aggregate of profiles of a component contained per unit area in multiple sections and an aggregate of profiles contained per unit volume. A linear scanning device (micrometer component quantitator) was initially employed for quantitative analyses of pancreas. This quantitative technique has subsequently been applied to normal rat ileum conventionally processed for light microscopy, and the requisite sampling parameters have been defined. An identical technique was then applied to physiologically manipulated rat ileum--a gnotobiotic group, a group with ileal self-filling blind loops, and a group with ileal Thiry-Vella loops. The results observed support the following conclusions. The volume percentage of the various components of the rat ileal wall of control animals was defined utilizing the micrometer component quantitator. Hypertrophy of the ileal muscularis externa within the ileal self-filling blind loops was observed, probably secondary to mechanical obstruction. Atrophy of the ileal epithelium within the gnotobiotic group and within the Thiry-Vella loops was observed, possibly secondary to an altered endogenous microbial flora. Recognition of quantitative variations among the histological components of the intestinal wall in association with physiological manipulations or pathologic states was (is) feasible by utilization of this component quantitative technique.

Animals↗

Postgraduate surgical flexible endoscopic education.

Postgraduate surgical education of residents in flexible gastrointestinal endoscopy is mandated by the American Board of Surgery. In that context, a retrospective analysis was performed of the general medical and endoscopic records of patients who experienced diagnostic and therapeutic flexible endoscopy during an 18-month period at the University of South Alabama Medical Center by surgical residents under the supervision of attending surgical endoscopists. That analysis revealed these procedures to be safe (diagnostic and therapeutic flexible endoscopy: morbidity incidence 0.4% and 2.2%, mortality incidence 0.2% and 1.1%, respectively), accurate (100%), and therapeutically beneficial (19% of the flexible endoscopic procedures were performed with therapeutic intent). Review of cumulative resident case profiles revealed that during the course of their clinical education (5 years), each resident performed approximately 400-500 endoscopic procedures, functioning successively as first assistant, primary endoscopist, and teaching assistant. The authors contend that: supervision by surgical endoscopists ensures safety and efficacy of the procedures during the education of postgraduate surgical residents; the surgical milieu--integration of endoscopic, surgical anatomic, and histopathologic data--provides the most effective educational format to acquire the skills necessary to achieve a high degree of accuracy associated with these endoscopic procedures; and therapeutic flexible endoscopy obviated the necessity for more invasive surgical procedures in approximately one-fifth of this patient population.

Adolescent↗

Crotalidae envenomation.

We treated 18 patients who had Crotalidae envenomation between January 1980 and September 1984. Primary antivenin therapy minimized morbidity and obviated mortality. More specificially, judicious though quantitatively sufficient antivenin therapy made surgical intervention unnecessary. We review the literature on Crotalidae anatomy, venom toxicology, and the envenomation syndrome.

Adolescent↗

Rapidly advancing pseudotumor cerebri associated with morbid obesity: an indication for gastric exclusion.

Although most cases of pseudotumor cerebri spontaneously remit or respond to brief courses of medical management, a minority will be chronic or recurrent and may be associated with progressive visual impairment. We have described a morbidly obese patient with rapidly advancing pseudotumor cerebri who had a gastric exclusion procedure, which resulted in weight loss and stabilization of the visual deficit.

Adult↗

Percutaneous endoscopic gastrostomy.

Gastric access for nutritional support can be accomplished by employing percutaneous and flexible endoscopic techniques. Between September 1, 1983 and March 1, 1985, 20 patients at the University of South Alabama Medical Center (USAMC) underwent percutaneous endoscopic gastrostomy (PEG). Retrospective analysis of this patient population revealed no periprocedure morbidity or mortality. All gastrostomy tubes were employed indefinitely and changed periodically commensurate with optimal care. This technique represents a useful addition to the general surgeon's armamentarium for gaining gastric access.

Adult↗

Valva ileocaecalis: preservation during ileocolonic surgery employing a rodent experimental model.

Experimental and clinical data suggest that the valva ileocaecalis under neurogenic and hormonal influences, modulates antegrade and retrograde flow of succus entericus. A priori reasoning suggests that this function may influence nutrient absorption by and intraluminal endogenous microbial flora within the ileum. The hypothesis to be tested was, can anatomical and functional integrity of the valva ileocaecalis be preserved during the performance of a right hemicolectomy with reestablishment of intestinal continuity via a cecocolostomy? The methodology involved utilization of Lewis male rats weighing approximately 500 gm. General anesthesia was induced for all procedures. The animals were randomly assigned to three groups (10 animals/group): (A) sham operation; (B) pericecal dissection (preservation of the arteria et vena ileocolica); and (C) periileal dissection (ligation of the aforementioned vessels). Celiotomy was performed employing standard clean techniques, and was accompanied by a right hemicolectomy and an end-to-end or end-to-side cecocolostomy. Function of the heterotopic valva ileocaecalis was assessed 6-12 weeks post-operatively employing radiographic criteria (fluoroscopic analysis after intraluminal instillation of barium sulfate). Light microscopic analysis was performed subsequent to the radiographic studies. Periileal dissection associated with ligation of the arteria et vena ileocolica uniformly resulted in anastomotic disruption. Pericecal dissection associated with preservation of those vessels resulted in uniform anastomotic integrity, although two animals succumbed secondary to pneumonitis within 5 post-operative days. Radiographic analysis of the heterotopic valva ileocaecalis revealed intermittent antegrade and no retrograde flow of contrast material, which suggested functional integrity. Qualitative light microscopic analysis revealed architectural integrity.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Gastritis cystica profunda.

Benign gastric pseudotumor, gastritis cystica profunda, possess malignant histological features but functionally behave benignly. The case reported herein is illustrative of this entity, but in contrast to previous reports developed without an antecedent history of gastric surgery. A cumulative experience with this entity suggests that it represents a manifestation of a spectrum of hyperplastic and metaplastic responses to mucosal injury.

Gastritis↗

Extraction of an intrapleural foreign body with a flexible endoscope.

A polyethylene catheter inadvertently sheared off during a diagnostic thoracentesis was successfully extracted with a flexible endoscope. Coincidentally, excellent visualization of the entire pleural space was noted. The procedure was performed with the patient under general anesthesia and sterile technique was employed. The patient sustained no untoward consequence. Coelomic analysis with a flexible endoscope may be appropriate in other diagnostic and therapeutic circumstances.

Aged↗

Suppurative pylephlebitis due to pseudodiverticulosis coli.

Patients manifesting suppurative pylephlebitis and intrahepatic abscess formation secondary to pseudodiverticulosis coli and acute diverticulitis are uncommon, but have very high morbidity and mortality. As illustrated by this case report, the symptoms and signs such a patient manifests are nonspecific and the diagnostic modalities available may be insufficiently sensitive. The therapeutic options available at present are excision and drainage of any detected extrahepatic or intrahepatic septic focus and prolonged antibiotic administration.

Adult↗