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Biomedical subjects

C Anastasatu

Publications and source records attributed to C Anastasatu.

At least 55 records · Page 3Linked to original sources
PubMedDate not supplied

[The late results of short-term chemotherapy in benign forms of tuberculosis in children].

The study included 359 cases of primary tuberculosis (benign forms) in children aged 0-14 years, out of which 181 non-complicated and 178 complicated forms. The therapeutical regimens were: 3HEZ2/3HE2 (study subgroup) and 6HE2/3H2 (control) for non-complicated forms, and 3HRZ2/3HR2 (study subgroup) and 3HES2/3HE2/3H2 (control) for complicated ones. Late results (5 years after treatment end) were very good (from clinical, radiological, bacteriological points of view) in 100% of cases. Thus, short-course regimens are preferable to longer ones (over 6 months) in the chemotherapy of the benign forms of pulmonary tuberculosis in children.

Adolescent↗
PubMedDate not supplied

[Contribution of pulmonary scintiscanning to the diagnosis of chronic obstructive bronchopneumopathy].

In a lot of 32 cases of chronic obstructive bronchopneumopathy, a correlation was established between the extent and location of the regional perfusion deficiencies (studied by scintigraphy) and overall functional disturbances Vmax MEVS X 100VC, residual volume, R, PaO2, PaCO2). In 85% of the cases regional perfusion disturbances were detected and grouped into six scintigraphic types. A good correlation was found between these disturbances and the MEVS X 100/VC index and modified partial pressure of the gases (O2, CO2) in the arterial blood. Unexpected was the absence of a mathematical correlation between perfusion disturbances and the residual volume and R, suggesting the great variety of the disturbances grouped under the general denomination of chronic obstructive bronchopneumopathy.

Adult↗
PubMedDate not supplied

[The recovery of work capacity within the framework of short-term antitubercular chemotherapy].

The authors compare the results of chemotherapy reflected in the proportion of recoveries of work capacity and the number of retired persons in two groups of patients--one including 102 cases treated between 1970 and 1971 by a 3/6 regimen, and another one including 91 patients treated in 1986 by a modern intensive 3 + 3 regimen. The data indicate better results with the 1986 lot as compared with the 1970-1971 lot. In the 1986 group there were no fatalities and the persons that recovered their work capacity represented 90.1% of the total. By contrast, in the group treated between 1970 and 1971 there were two fatalities and only 84.3% of all the patients did recover the work capacity. The number of retired persons decrease from 11.7% in the first group to 7.7% in the second. Temporary incapacity decreased from an average of 321 days to an average of 267 days in the second group. All these results were obtained by shortening the treatment from an average of 9 months to an average of 6 months.

Absenteeism↗
PubMedDate not supplied

[Disodium cromoglycate treatment of bronchial asthma and spastic bronchitis (preliminiary results)].

After a short review of the mode of action of sodium chromoglycate, the results are presented, of the treatment carried out over a three months period in a group of 31 patients of which 23 had bronchial asthma and 8 had spastic bronchitis. In 19 cases the doses of steroids that the patients were receiving were either diminished or supressed, in 14 cases the doses of broncho-dilating drugs were diminished or supressed and in 15 cases the results of the respiratory function tests were improved or much improved. A synthetic evaluation of the clinical and laboratory results showed that in 3/4 of the cases (74.2%) these were either favourable or very favourable. The treatment was well tolerated and no side-effects were noted.

Adult↗
PubMedDate not supplied

[Factors in the failure of tuberculosis chemotherapy studied in a Romanian county].

This work proposes to analyse the quality of the failure risks in the case of a short duration treatment applied in operational conditions on the territory of Constanţa County as a premise for the application of a method of mathematical analysis on computer in view of predicting the failure cases. There were studied 262 eligible cases out of 290, which represent the total of the patients newly registered with pulmonary tuberculosis in 1982, on the territory of Constanţa County and who were kept an eye upon for 3 years after finishing the treatment. There resulted 58 (22.1%) recurrencies, failures or corrected in course intratherapeutic positive reactions, on which were analysed 25 possible failure factors. The most representative have proved to be the organizational factors among which irregular treatment (67.2%) of the failure cases, a defective mobilizing to treatment, technical factors: late negativation of sputum (over 4-5 months from starting the treatment), and among the factors depending on the patients--noncooperation occurred in 60.33% of the failure cases. If the final frequency of failures on the territory of Constanţa County does not exceed the average figures recorded here and abroad, the global frequency within the studied time period is not satisfactory and imposes an assessing of the failure factors and measures of improvement.

Age Factors↗