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Biomedical subjects

C Adamsbaum

Publications and source records attributed to C Adamsbaum.

17 recordsLinked to original sources
PubMed1992

Diagnosis and treatment of ossification of the posterior longitudinal ligament of the spine: report of eight cases and literature review.

PURPOSE: Ossification of the posterior longitudinal ligament (OPLL) is a common, well-recognized cause of spinal stenosis and myelopathy in Japan. Although also common in whites, especially among the elderly, it has received little scientific attention. We wish to increase awareness of this important cause of myelopathy, and to determine if the clinical characteristics of OPLL are similar in non-Japanese and Japanese patients. PATIENTS AND METHODS: The clinical and radiologic features of eight cases of OPLL are presented. These cases combined with 73 non-Japanese cases gathered from the English literature are contrasted with 2,125 Japanese cases of OPLL. RESULTS: Similarities among non-Japanese and Japanese cases included: (1) male predominance; (2) peak age at onset of symptoms in the sixth decade; (3) clinical presentation, which ranged from asymptomatic to quadriplegia, with progressive or acute onset of neurologic deterioration; (4) greater than 95% localization to the cervical spine, spastic quadriparesis being the most common neurologic presentation; (5) an association with several rheumatic conditions including diffuse idiopathic skeletal hyperostosis (DISH), spondylosis, and ankylosing spondylitis; and (6) neurologic improvement with either conservative or surgical treatment in a significant proportion of patients. Differences between the two groups were minimal and included a higher mean age at onset (although onset in both groups occurred within the sixth decade) and a greater proportion of patients with DISH and with the continuous type of OPLL in the non-Japanese group. CONCLUSION: The clinical characteristics of OPLL are similar in Japanese and non-Japanese patient populations. Increased awareness of this condition, which has potentially devastating neurologic complications, will favorably influence diagnosis, treatment, and outcome.

Adult↗
PubMed1992

Brain MRI and electrophysiologic abnormalities in preclinical and clinical adrenomyeloneuropathy.

We describe the neurophysiologic abnormalities in 17 patients with clinical adrenomyeloneuropathy (AMN), an adult phenotype of X-linked adrenoleukodystrophy (ALD). These abnormalities also allowed the early recognition of the AMN phenotype in three asymptomatic boys with biochemically proven ALD. In 14/16 adult AMN patients, there were cerebral white matter abnormalities on MRI which were severe and comparable with cerebral ALD in four of the patients.

Addison Disease↗
PubMed1992

[Ioversol 300: clinical study in pediatric intravenous urography].

The efficacy and safety of Optiray (Ioversol), a new low osmolar non ionic contrast agent, were evaluated in an open trial for pediatric intravenous urography. At a concentration of 30% iodine, Optiray had a good diagnostic efficacy and was found to be well tolerated.

Adolescent↗
PubMed1992

[Hamartoma].

Explore the source record for details and available documents.

Brain Neoplasms↗
PubMed1992

[Neonatal cervical cord compression by a staphylococcal abscess].

In a small for date premature newborn infant, septicemia caused by Staphylococcus aureus was observed on day 16. In spite of an appropriate antimicrobial therapy, proteins of inflammation serum levels remained elevated for 2 weeks. The occurrence of cervical cord compression which could be related to a staphylococcal abscess explained the persisting inflammatory process. After puncturing of the abscess, immobilization and prolonged antibiotic treatment, outcome was favorable. This case demonstrates the difficulty of preventing abscesses related to staphylococcal septicemias and reports a very unusual site of abscess which could be well localized using MRI.

Abscess↗
PubMed1992

[A retrospective study of preadoption x-ray findings in young children at the Social Child Aid: value and limitations].

French law requires that children awaiting adoption undergo full medical evaluation to detect anomalies which may influence decisions concerning adoption. As part of this evaluation, all infants admitted to the Saint-Vincent-de-Paul Preadoption Center in Paris undergo roentgenographic evaluation including frontal and lateral films of the skull, a frontal chest film, a frontal view of the pelvis, and frontal films of one upper limb and one lower limb. A study of the one hundred most recent evaluations, carried out in infants aged 1 to 14 months, disclosed 16 roentgenographic anomalies. Five of these anomalies were already known prior to the evaluation, 2 did not give rise to additional investigations, and 9 led to additional tests, a change of therapy or subsequent radioclinical monitoring. Among the six films taken in each patient, only the frontal views of the chest and pelvis proved informative. Screening using these two roentgenograms only is recommended, with other roentgenograms being performed if called for on the basis of clinical findings.

Adoption↗
PubMed1991

Contribution of MRI to the diagnosis of cerebral lesions of adrenoleukodystrophy.

33 cases of adrenoleukodystrophy in children have been studied. Brain MRI was performed in these patients in order to appreciate the benefits of this technic in patients presenting with the cerebral type of ALD [21]. 12 neurologically asymptomatic patients with the same biochemical disorder were studied. In both groups, MRI is the best imaging modality. In symptomatic patients lesions were clearly demonstrated with excellent clinical correlations. In addition, MRI can depict brain lesions in asymptomatic patients before devastating brain damage occurs. MRI is the essential step before proposing specific treatment to these patients.

Adolescent↗
PubMed1991

Minor tibial duplication: a new cause of congenital bowing of the tibia.

Five infants presented with a congenital anterolateral, unilateral bowing of the tibia. The fibula was normal but a bifid homolateral great toe was seen, associated with hand malformations. Plain films and CT disclosed a short tibial duplication, with distinct corticals. We do think that this abnormality represents a new entity, and may be related to a genetic anomaly. The long term follow up of our patients shows a spontaneously favourable prognosis without any association with pseudarthrosis. The only therapeutic problem is a limb length discrepancy.

Abnormalities, Multiple↗
PubMed1989

[Zollinger-Ellison syndrome of ovarian origin. Apropos of a case with a review of the literature].

We report a case of Zollinger-Ellison syndrome due to secretory G and D cells in an ovarian mucinous cystadenoma. Surgical resection of the tumour led to disappearance of clinical symptomatology and laboratory signs. Four other cases were found in the literature. The prognosis of the Zollinger-Ellison syndrome, due to a secretory ovarian tumour, appears to be favourable after oophorectomy.

Adult↗
PubMed1988

Sonographic hepatic arterialisation in newborns receiving parenteral nutrition.

Two cases of severe liver disease with portal hypertension in the newborn are reported. Such complications occurred after necrotizing enterocolitis requiring total parenteral nutrition and digestive exclusion for a long time. Ultrasonography showed an hepatic arterialisation with portal hypertension.

Enterocolitis, Pseudomembranous↗
PubMed1988

[Disk hypodensity and disk herniation].

The authors report the case of a patient with a herniated lumbar disk and bacterial meningitis. CT scan showed central disk hypodensity at the hernia level, whilst full cytological and bacteriological study of the disk following surgery revealed no evidence of spondylodiscitis. The problem was thus that of consequences of "degenerative" events related to the herniation. Central or peripheral disk hypodensity must in no case be considered as specific of discitis when there is a concomitant disk herniation.

Aged↗
PubMed1988

[The labrum acetabular. Apropos of 121 arthrographies of the hip in adults].

The authors report a retrospective study of 121 arthrographies of the hip in adults, excluding prostheses. The study was based on normal pathological values for angular measurement of the labrum acetabular: ECB angle (mean value: 15 degrees) enlarging the lateral cover of the head of the femur, VCE angle (mean value: 30 degrees) and a mean global VCB angle of 45 degrees. A certain equilibrium was observed between the covering capacity of the acetabulum and the covering capacity of the labrum acetabular. Numerous anomalies of the labrum were observed, including fissures in about 30% of cases. A large number of fissures were associated with other degenerative anomalies of the hip joint. A few fissures resulting in detachment of a strip of labrum were isolated and the possibility of their traumatic etiology and their pathogenic nature in clinical symptoms are discussed.

Acetabulum↗
PubMed1985

Age-specific differences in duration of clinical protection after vaccination with meningococcal polysaccharide A vaccine.

Sequential case-control studies were used to monitor changes in the clinical protection induced by group A meningococcal polysaccharide vaccine over a 3-year period. Overall, vaccine efficacy declined from 87% 1 year after vaccination to 70% and 54% at 2 and 3 years, respectively. When stratified by age at time of vaccination the data showed that, although vaccine efficacy remained high in children greater than or equal to 4 years of age (vaccine efficacy 85%, 74%, and 67% at 1, 2, and 3 years after vaccination, respectively), it declined dramatically in those less than 4 years of age at time of vaccination (vaccine efficacy 100%, 52%, and 8%, respectively, at 1, 2, and 3 years after vaccination). Thus, a single dose of group A meningococcal vaccine does not yield lasting clinical protection in children less than 4 years of age.

Adolescent↗
PubMedDate not supplied

[Efficacy of x-ray computed tomography in the diagnosis of tumors of the mediastinum. 103 cases].

A prospective study was carried out in 103 patients with mediastinal tumors to determine diagnostic value of CT imaging. A precise diagnosis was obtained in 80% of cases, the detection sensitivity being 100%, 98% and 71% respectively for fatty tumors (20 cases), solid tumors (59 cases) and cystic tumors (24 cases). The weak sensitivity of detection of cystic tumors was due to the spontaneously elevated density of mediastinal cystic tumors and the fact that 2 patients in this series with cystic lesions presented enhanced images with contrast. Sensitivity of detection of a malignant tumor was only 59%, due mainly for thymic tumors to extracapsular microscopic extensions undetected by CT scanning, which should however be included in exploratory techniques for mediastinal tumors.

Humans↗