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Biomedical subjects

C Adams

Publications and source records attributed to C Adams.

At least 217 records · Page 12Linked to original sources
PubMed1979

Immunoreactive somatostatin release from rat spinal cord in vitro.

A calcium-dependent release of immunoreactive somatostatin from rat spinal cord in vitro in response to two depolarising stimuli (60 mM KCl and 75 micrometer veratrine) has been demonstrated. Released somatostatin immunoreactivity comprised 0.53% of total tissue content, showed parallelism when serial dilutions were compared to the immunoassay dose-response curve and eluted similarly to synthetic somatostatin on Sephadex G-25 (f) chromatography. These results provide further evidence for a neurotransmitter or neuromodulator role for somatostatin in mammalian spinal cord.

Animals↗
PubMed1979

Dimensional preferences in middle and old age.

Dimensional preferences in 40 middle-aged (M = 41.62 years) and 40 elderly (M = 72.22 years) females were assessed using a dimensional choice task. Significant age differences in reaction times of choice but not in number of dimensional choices were obtained. There was a perfect rank-order correspondence between the two age groups in dimensional choices with form being the most preferred and color the least preferred perceptual dimension.

Adult↗
PubMed1979

Endobronchial polyposis secondary to thermal inhalational injury.

A 28-year-old man who sustained inhalational injury in a house fire developed symptoms of chronic cough and hemoptysis requiring bronchoscopy. Two months after the initial injury, numerous endobronchial polyps were found in the trachea and throughout the bronchial tree. His symptoms have subsequently improved over a six-month period while receiving steroid therapy. To our knowledge, this delayed complication of inhalational burn injury has not been previously reported.

Adult↗
PubMed1978

In search of the acoustic correlates of stress: fundamental frequency, amplitude, and duration in the connected utterance of some native and non-native speakers of English.

In this investigation of the correlates of stress, account was taken of both production and perception aspects of the phenomenon in the connected utterance of a group each of native and non-native speakers of English. Measurement of the fundamental frequency, amplitude, and duration of the syllables stressed by these subjects revealed that duration was by far the most frequently used cue and that amplitude was the least used. The two groups differed significantly both in the incidence and placement of stress, although no evidence was found to suggest that native and non-native speakers consistently employ different acoustic parameters to signal this feature at the sentence level.

Acoustics↗
PubMed1977

17beta-oestradiol and Enovid mammary tumorigenesis in C3H/HeJ female mice: counteraction by concurrent 2-bromo-alpha-ergocryptine.

Chronic administration of 17beta-oestradiol (via drinking water) or the oral contraceptive Enovid (norethynodrel and mestranol) (0-1 mg injected s.c. twice weekly) to nulliparous C3H/HeJ female mice, beginning at one month of age and terminating at 20 months (17beta-oestradiol) or 22 months (Enovid), significantly increased the incidence of mammary tumours over solvent-treated controls. Concurrent treatment of the steroid-treated mice with 2-bromo-alpha-ergocryptine (CB-154) (0-1 mg s.c. injected daily) significantly reduced mammary tumour incidence and mammary hyperplastic nodule development to the control level. CB-154 is an efficacious inhibitor of pituitary prolactin secretion. These results demonstrate that steroid-induced mammary gland dysplasias can be sharply reduced by chronic CB-154 treatment, and suggest that some of the mammary tumorigenic activities of oestrogenic steroids in C3H mice are mediated via an increased secretion of pituitary prolactin.

Animals↗
PubMed1976

The effects of stimulability on the articulation of /s/ relative to cluster and word frequency of occurrence.

This study investigated the effects of stimulability on the articulation of cluster nested /s/ in high- and low-frequency clusters and words. A good stimulability group and a poor stimulability group of /s/-defective seven-year-old children were investigated. Statistical analysis did not reveal significant differences between the articulatory performances of the two groups on words or clusters occurring with high or low frequency. Subjects in the good stimulability group obtained significantly fewer errors on the test stimuli than did subjects in the poor stimulability group. Correlational analyses indicated that stimulability was positively correlated with correct numbers of /s/ productions in both clusters and words occurring with both high and low frequency. Subjects' spontaneous /s/ errors on the Templin-Darley screening test were not found to be correlated with their stimulability scores or their imitative /s/ productions in words and clusters occurring with high or low frequencies.

Acoustic Stimulation↗
PubMed1975

Cerebro-hepato-renal syndrome of Zellweger. A report of eight cases with comments upon the incidence, the liver lesion, and a fault in pipecolic acid metabolism.

Studies of eight patients with this syndrome confirm the characteristic pattern of abnormalities and the autosomal recessive mode of inheritance. The incidence is estimated to be approximately 1 in 100,000 live births. The liver lesion proved to be variable, with features of progressive parenchymal damage rather than a developmental defect of small bile ducts as previously suggested. Elevated levels of pipecolic acid were found in blood and urine and may be related to the basic defect.

Acidosis↗