Comparative effect of glucose feeding on the activities of some liver and heart enzymes in rats.
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Biomedical subjects
Publications and source records attributed to B W Smith.
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Two networks of medical care have grown up in Japan: 1 network based in hospitals and 1 based in private clinics. Most physicians in clinics practice general medicine, although only a small proportion of them are trained in primary care. Postgraduate medical education is oriented toward the training of specialists. Owing to the impending retirement of the cohort of clinic-based physicians who have dominated medical politics in Japan, the system is expected to change substantially in the next decade. Among the reformers is a small group of physicians who are attempting to introduce family practice.
OBJECTIVE: The purpose of this study was to examine the role of depressive symptoms in reactivity to stress and pain in older women with rheumatoid arthritis (RA) and osteoarthritis (OA). METHODS: Participants were 188 older women with RA (N = 87) and OA (N = 101). They were initially assessed for depressive symptoms and interviewed weekly for 12 to 20 weeks regarding interpersonal stress, arthritis pain, and negative affect. RESULTS: Hierarchical linear modeling (HLM) revealed that depressive symptoms were related to weekly elevations in arthritis pain, negative events, perceived stress, and negative affect for RA respondents and elevations in arthritis pain and negative affect for OA respondents. HLM analyses also indicated that depressive symptoms were related to increased reactivity to perceived stress and arthritis pain in people with RA, but not those with OA. CONCLUSIONS: Depression may be related to elevations in pain for people with RA and OA and to elevations in stress and increased reactivity to stress and pain for those with RA.
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This study explored the performance of experienced laboratories in the analysis for total selenium in water by a variety of analytical methods. The goal of the study was to examine intra- and interlaboratory variability. Replicates (n = 7) of 7 sample types that included a reference material of known Se concentration, natural waters, and treated wastewaters were submitted to 7 laboratories with prequalified Se analytical experience. Results of the study indicated wide ranges in minimum and maximum results, distinct differences in laboratory precision, and routine reporting of numerical results below statistical limits of quantitation. Hydride generation as a sample introduction technique demonstrated superior performance. In general, the study supports a caution advisory about using low-level Se data, especially results lower than about 10 micrograms Se/L, without quantitating the statistical uncertainty of the data. Because this study used data from samples that were submitted in bulk to participating laboratories prequalified for Se analytical expertise and experience, it can be considered a best-case demonstration of performance.
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