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Biomedical subjects

B W Long

Publications and source records attributed to B W Long.

14 recordsLinked to original sources

H2-Histamine receptor blocking agents in the Zollinger-Ellison syndrome. Experience in seven cases and implications for long-term therapy.

H2-Histamine receptor blocking agents metiamide and cimetidine were assessed in seven patients with Zollinger-Ellison syndrome (serum gastrin greater than 300 microgram/ml, basal acid output greater than 15 meq/h, ratio of basal acid output to maximal acid output greater than 0.5). Intravenous or oral administration of the drugs lowered acid secretion by at least 70% in all cases. Subsequent treatment of six patients for 3 to 15 months (oral therapy) and one patient for 1 month (intravenous therapy) showed that the drugs abolished symptoms in all seven, abolished diarrhea in five, allowed ulcer healing in six, and were well tolerated without adverse effects in seven. No patient failed to respond to the drug, although one died from tumor progression and two required total gastrectomy for complex reasons. The results indicate that patients with Zollinger-Ellison syndrome can be managed medically and, in light of current mortality trends, gain little from the extra risks attending total gastrectomy.

Adult

Ischemic colitis.

Explore the source record for details and available documents.

Angiography

A double-blind, randomized, sham-controlled trial of the gastric bubble for obesity.

We investigated the effect of an endoscopically placed gastric balloon, the Garren-Edwards gastric bubble (GEGB), on weight loss in obese patients. Fifty-nine obese patients were entered into a prospective double-blind study and randomized into two groups. In one group (34 patients) the GEGB was inserted, and in the other group (25 patients) a sham insertion was done. All patients participated in a standard weight loss program consisting of dietary therapy, behavior modification, and physical exercise. The bubble was removed endoscopically after 3 months from both groups. Patients were followed for an additional 9 months after bubble removal and weight loss was monitored. Weight loss was the same in both groups at 3 months (18.7 lb vs. 17.2 lb). This was true whether determined by change in pounds, percentage of body weight, or body mass index. We concluded that the GEGB was of no added benefit as compared with sham insertion, when combined with a standard weight loss program. Because of the lack of proven efficacy and the relatively high cost, we recommend that such devices be restricted to controlled studies until significant benefits are proven.

Adult

Showing acetabular trauma with more clarity, less pain.

Standard radiographic projections may not provide a complete diagnosis of acetabular fractures, which often are the result of an automobile accident or other injury applying severe force to the femur. The Judet oblique projection of the pelvis and a variation described by the authors reduces patient risk and discomfort while demonstrating fractures not clearly seen on routine radiographs.

Acetabulum

Technique for diagnosis of scaphoid fractures.

Fracture of the scaphoid bone accounts for 60 percent of all carpal injuries. Early diagnosis of a scaphoid fracture is extremely important. Missing the fracture may lead to disability due to potential avascular necrosis or non-union of the fragments. The presence of a scaphoid fracture may be determined with greater certainty by using a multiple angle scaphoid series detailed by the author.

Adult

Apicoaortic valved conduits in a canine model.

Evaluating new developments in surgical methods and materials of aortic bypass prosthetics requires the use of an appropriate animal model, a well established surgical protocol and post surgical aortography. This article describes the surgical technique, post operative care and the angiographic technique used for an apicoaortic conduit placement in a canine model.

Animals

Balloon expandable intraluminal vascular stent.

The percutaneous, intraluminal placement of an expandable arterial stent is a new method for reducing stenosis in atherosclerotic arteries. This method, used in conjunction with balloon angioplasty, involves the placement of metallic mesh stent at the sight of the stenosis. Use of this technique has resulted in various improvements over angioplasty alone.

Aged

Axillary shoulder with exaggerated rotation: the Hill-Sachs defect.

One of the most common fractures of the humeral head resulting from an anterior dislocation is the Hill-Sachs defect. Other special radiographic positions to demonstrate this injury may prove difficult for the patient to assume and maintain. An axillary shoulder projection with exaggerated external rotation is easy to position and clearly demonstrates the Hill-Sachs defect.

Adult

Image enhancement using computed radiography.

Computed radiography (CR) is emerging as a digital imaging modality for use in conventional radiography. An advantage of CR over film-screen systems is the separation of image acquisition, processing and display. Selection of many different image display characteristics are possible. The system is also able to alter or enhance image details after the radiographic examination has been completed.

Humans

Computed radiography: photostimulable phosphor image plate technology.

Computed radiography is emerging as a digital imaging modality for use in conventional radiography. It is based on photostimulable phosphor image plate technology. The image plate (IP) is housed in a cassette similar to a standard radiographic cassette. The IP phosphor retains a latent image of the energy pattern to which it was exposed. This latent image is "read" as it is released from the phosphor by laser light exposure. The image is laser printed on 10 in x 14 in film.

Computer Systems