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Biomedical subjects

B Terwey

Publications and source records attributed to B Terwey.

At least 37 records · Page 2Linked to original sources

Unusual combination of cerebral dysplasias. Report of two cases.

Two types of a rare combination of cerebral malformations originating from parenchymal and/or vascular developmental disorders are described. In the first case, there is a coincidence of aneurysm, AVM, persistent trigeminal artery and arachnoid cyst. In the second case a giant infratentorial aneurysm, dural AVM and haemangioma of the neck are combined. The underlying disturbances of gestation in the multiple dysplasias are discussed in their embryological context. Both cases were considered by neurosurgeons as well as neuroradiologists to be untreatable.

Adolescent↗

Dynamic studies of cervical spinal canal and spinal cord by magnetic resonance imaging.

In 15 cases dynamic studies of cervical spinal cord and canal in flexion and extension were performed by magnetic resonance imaging (MRI). In addition measurements of the complete spinal cord were made in 5 cases. As compared with extension the cervical spinal canal and spinal cord lengthen 12 mm in average during flexion, whereas the spinal canal lengthens 28 mm in average, which means a difference of about 15 mm. We feel that these results indicate that adverse mechanical tension may occur in the cervical spinal cord during flexion. The impact of these results on surgical treatment for chronic cervical myelopathy is discussed.

Humans↗

Vascularization of malignant testicular tumors.

Recent studies of malignant testicular tumors report a correlation between vascularization, biologic behavior, radiosensitivity, and chemotherapeutic response of the tumor. Postoperative angiographies of malignant testicular tumor specimens (seminoma n = 4, nonseminoma n = 12) showed the following results: Contrary to the symmetric vascularity pattern of normal testes, seminomas were hypovascular, well-defined from normal testicular tissue and not neovascular. Nonseminomas showed isovascularity (n = 5) or hypovascularity (n = 7) but with focal hypervascular areas in the tumor (n = 10), and pathologic neovascularization. Present angiographic studies reveal marked differences in the vasculature pattern of malignant testicular tumors. In nonseminomas, focal hypervascular or neovascular areas as centers of a high-growth rate correlate well with comparable cell kinetic studies. Assuming a similar growth behavior in metastases, the vascularization type of these growth centers theoretically favors the efficient use of chemotherapeutic agents.

Arteries↗

[Computed tomography and nuclear spin tomography in peripheral lymphedema].

The first reported findings on CT and N.M.R. in two cases of idiopathic peripheral lymphoedema are described. These methods have compared with the generally available volume estimations (volume estimation according to Kuhnke, immersion plethysmography) and have been considered in relation to visual and lymphographic examinations.

Adult↗

[B-image sonography of carotid bifurcation].

The main purpose of noninvasive high-resolution B-mode sonography of the extracranial carotid artery is to detect clinically relevant arteriosclerotic lesions. That is the reason why reproducible parameters are needed for the description of normal and pathological echo patterns of the vascular lumen and the vascular wall. From an experimental evaluation of 100 carotid specimens examined with a high resolution real time scanner a list of definitions for sonomorphologic parameters is derived. These parameters refer to the clinical importance of luminal and intramural changes. Because of its high sensitivity for even minimal arteriosclerotic lesions, B-mode sonography is a useful method for clinical and epidemiological studies of extracranial carotid disease.

Brain Ischemia↗

[Indications for surgery of carotid artery stenosis with contralateral carotid occlusion].

In a retrospective study the course of 69 patients of the Surgery Department of the University of Heidelberg (66 men, 3 women, mean age 60 years) with carotid artery stenosis with contralateral carotid occlusion has been reported. 10% of the patients with carotid artery stenosis had a contralateral occlusion. Corresponding to the side of occlusion most patients had a preoperative neurological stage IV (55%, 19% stage II, 26% stage I) and corresponding to the side of stenosis most patients had a stage I (57%, 28% stage II, 4% stage III, 12% stage IV). In addition to the stenosis the occlusion had been operated on in 7 patients, in 5 of them the revascularisation was not possible. In 88% the arteriotomy could be closed using a venous patch and in 97% a intraluminal shunt was used. All operations were done under general anesthesia. The early lethality rate was 10%, in one patient a postoperative neurological deficit occurred. The late mortality rate was 21%, in 5% a new neurological deficit could be found (n = 57, mean follow-up: 3.0 years). In relation to the preoperative neurological stage corresponding to the side of stenosis the highest mortality rate was found in patients with stage IV. In a separate analysis of two periods (1962-1978 and 1979-1981) it can be demonstrated that the high early mortality rate is nearly entirely found in the first period with a low operative frequency. In the second period 1979-1981, 33 carotid endarterectomies in patients with contralateral occlusion were operated with a mortality rate of 3%.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Catheter embolization following median sternotomy.

A case of intraoperative internal jugular vein catheter embolization in a patient undergoing median sternotomy for open-heart surgery is described. This complication suggests that right sided cannulation of the internal jugular vein is to be preferred in all patients having a median sternotomy in order to avoid the risk of intersection by median sternotomy.

Brachiocephalic Veins↗

[The "spill-over" method for flow measurements].

"Spill-over" measurement is a simple method for estimating arterial blood flow during selective angiography. It depends on a direct comparison between a known contrast flow rate and the unknown blood flow in the aortic branch that is being examined. The criterion crucial to the measurement is the back-flow of contrast into the aorta. By means of model and animal experiments, it has been established why back-flow occurs and which factors favour or retard back-flow and thereby falsify the results. The results of "spill-over" measurements were compared with electro-magnetic measurements. A modification of the "spill-over" method is described, which makes it suitable for routine use in visceral angiography.

Animals↗

Complete regression of multiple pulmonary metastases in a patient with advanced renal cell carcinoma treated by occlusion of the renal artery with subsequent radical nephrectomy and progesterone.

We report on a 51-year-old male patient who presented with a renal cell carcinoma of advanced stage including multiple pulmonary metastases. A complete regression of the pulmonary metastases was observed after embolisation of the tumor-bearing kidney with subsequent nephrectomy and progesterone treatment. 27 months after the operation the patient is in excellent health without recurrence of metastases.

Adenocarcinoma↗

Microcalcifications in testicular malignancy: diagnostic tool in occult tumor?

Malignant testicular tumor microcalcifications are being reported at an increasing rate. However, whether or not the detection of microcalcifications had any clinical significance has not been clarified. In the the present study testicular specimens from 92 patients (43 with malignant and 49 with nonmalignant testicular diseases) were examined postoperatively by mammographic technique. Microcalcifications were identified in 32 of the testicular tumor specimens (74 per cent), more frequently in teratomas (87 per cent) than in seminomas (60 per cent), and in 3 "burned-out" tumors. In contrast, only 8 of the benign testicular specimens showed microcalcifications (16 per cent). The arrangement of microcalcifications as well as the distinct pattern of distribution may further discriminate nonmalignant from malignant entities. Though the rate of detection and allocation of microcalcifications in malignant testicular tumors was a surprising finding, the general use of orchioradiography seems problematic because of the risk of potential damage to the germinal epithelium. In occult carcinoma, however, preoperative or orchioradiography may be justified.

Calcinosis↗

[Flow measurements in the major visceral arteries (author's transl)].

Arterial flow was measured by the spill-over technique in 202 coeliac arteries and 158 superior mesenteric arteries during the course of visceral angiography in 250 patients. In the coeliac artery a mean value of 15.8 +/- 4.3 ml/sec was obtained, flow in the super mesenteric artery was significantly less at 12.1 +/- 3.4 ml/sec. The wide variation from 4 to 26 ml/sec in the coeliac artery was remarkable, as well as flows from six to 20 ml/sec in the superior mesenteric artery.

Blood Flow Velocity↗