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Biomedical subjects

B Singh

Publications and source records attributed to B Singh.

At least 901 records · Page 50Linked to original sources
PubMed1977

Cell-mediated immune response in equine babesiosis.

An intradermal skin test, to demonstrate a delayed cutaneous hypersensitivity reaction in Babesia equi infection in donkeys, was developed. A skin reaction to B. equi antigen was elicited in vaccinnated, infected and carrier intact and splenectomised donkeys. The histopathological examination of the skin biopsy revealed infiltration of mononuclear cells and accumulation of oedematous fluid in the deeper layers of the dermis. A leucocyte migration inhibition test was developed and its specificity as an in vitro measure of cell-mediated immunity to B. equi antigen was established. The results of this study demonstrated a correlation between cell-mediated immunity and protection.

Animals↗
PubMed1977

Altered enzyme release by virus infected mouse salivary glands.

The rates of release of salivary amylase and esterase from normal and polyoma virus infected mouse submandibular glands were measured in a continuous flow perifusion system. Following stimulation by epinephrine, the rate of release of esterase by the infected glands was significantly greater than that from control glands. The rate of amylase release, while greater from infected glands, was not significantly different. The total enzyme contents from infected and control tissues were similar. Cyclic GMP was found to be higher in the infected glands than the control glands, suggesting one possible mechanism for the higher rates of enzyme release by infected tissues.

Amylases↗
PubMed1977

Diagnosis and measurement of cyclodeviation.

A simple, convenient, and accurate method of detecting and measuring even the smallest degree of cyclodeviation with the help of two special major amblyoscope slides is described. Routine use of these slides in the investigation of all paralytic squints to detect and measure cyclodeviation is suggested. This will prove useful in the correct diagnosis and in the adequate management of a case of cyclovertical muscle palsy.

Humans↗
PubMed1977

Improved dynamic and static imaging of abdominal aortic aneurysms.

The authors describe a technique for rapid, convenient in vivo labeling of circulating erythrocytes with 99mTc and the application of this technique to the evaluation of abdominal aortic aneurysms. Dynamic perfusion images and equilibrium blood pool images were obtained in 9 patients with documented aneurysm, and 7 of them indicated an aneurysm on the radionuclide study.

Aorta, Abdominal↗
PubMed1977

Isatin enzyme interactions. V. Activation of rat liver acid phosphatase.

Influence of Isatin on rat tissue acid phosphatase has been studied. It has an organ-specific effect, the liver enzyme is activated, the brain enzyme is inhibited while those of kidney and intestine are not affected. Isatin activation of the liver enzyme is of mixed type and pH dependent. Rat liver enzyme appears to require intact amino and sulfhydryl groups for activity. Isatin seems to combine with the enzyme through the sulfhydryl group of the latter.

Acid Phosphatase↗
PubMed1976

99mTc-Sn-acetylcysteine: a new renal scanning agent.

A new radiopharmaceutical, 99mTc-Sn-acetylcysteine, for renal scanning is reported. The preparation is simple and quick. It can also be adopted in the kit form. The complex has the advantage of great stability and fast clearance over earlier reported renal scanning radioagnostic agents.

Acetylcysteine↗
PubMed1976

Virucidal effect of certain chemical contraceptives on Type 2 herpesvirus.

The virucidal effect of several chemical contraceptives was investigated and the findings are rrported. The supension of Type 2 herpes simplex virus, containing 10(6) to 10(7) tissue culture infectious doses per 0.1 ml., was inactivated on exposure to five different chemical contraceptives. For quantitative estimates of virucidal effect, 10 per cent solutions of these chemical contraceptives were tested with an exposure time of 10 minutes at room temperature. The methods for determination of residual infectivity included both virus assays in cultures of Vero cells and human embryo fibroblasts, as well as the intracranial inoculation of mice. Virus infectivity decreased 1,000- to 10,000-fold after contact with chemical contraceptives, indicating a substantial virucidal effect.

Animals↗