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Biomedical subjects

B Sethia

Publications and source records attributed to B Sethia.

59 records · Page 4Linked to original sources
PubMed1981

Giant aneurysm of membranous septum. Unusual cause of mediastinal mass.

A case of giant aneurysm of the membranous interventricular septum which presented as a mediastinal mass is described. Aneurysms of the membranous septum are rare and usually found incidental to the main cause of the patient's complaints. They are most commonly associated with ventricular septal defects but can also be found in the presence of ventriculoarterial discordance, atrioventricular canal defects, and semilunar valve abnormalities. In patients presenting with a mediastinal mass which may be cardiac, full left and right heart catheterisation are necessary; a simple right heart study is inadequate.

Adult↗
PubMedDate not supplied

Surgical closure of persistent ductus arteriosus (PDA) in infants before 30 weeks gestation.

Between October 1981 and December 1983 21 premature infants of mean gestational age 27.5 weeks (range 26-29 weeks) underwent surgical closure of persistent ductus arteriosus. Mean birth weight was 1080 g. There was no operative mortality. One death in an infant with pseudomonas septicaemia occurred two days after surgery. Twenty infants had features of idiopathic respiratory distress syndrome (IRDS) and required assisted ventilation prior to operation. Six infants had associated bronchopulmonary dysplasia (BPD) and 11 had signs of congestive cardiac failure. All infants presented with clinical features suggesting the diagnosis of PDA and in 18 the left atrial/aortic ratio was increased (mean 1.9:1). In 18 infants a trial of Indomethacin therapy had failed. This experience supports the view that surgical closure of PDA in infants born before 30 weeks gestation can be accomplished safely. We believe that surgical treatment of PDA represents the optimal therapy in this high risk group of infants.

Bronchopulmonary Dysplasia↗