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Biomedical subjects

B Sanders

Publications and source records attributed to B Sanders.

At least 37 records · Page 2Linked to original sources

Silicone rubber fossa implant removal via partial arthrotomy followed by arthroscopic examination of the internal surface of the fibrous capsule.

Thirteen temporomandibular joints were examined arthroscopically for evaluation for fibrous encapsulation of silicone elastomer disk replacement implants. Partial arthrotomies were performed with removal of silicone rubber implants, followed by arthroscopic examination of the internal surfaces of the fibrous capsule as a pseudodisk and to verify the continuity of the fibrous barrier between the condyle and the fossa.

Adult

Arthroscopic surgery for treatment of temporomandibular joint hypomobility after mandibular sagittal osteotomy.

Arthroscopic surgery is an effective method for treating painful hypomobility of the temporomandibular joint. Decreased range of motion after sagittal ramus osteotomies of the mandible has been reported. Causes may include intra-articular factors. These cases may be effectively treated with arthroscopic lysis and lavage after failure of nonsurgical modalities. A series of 15 patients is presented.

Adolescent

Inner-city women at risk for cervical cancer: behavioral and utilization factors related to inadequate screening.

This study investigated the relationships between health care utilization, knowledge, attitudes, sociodemographic characteristics, and adequacy of cervical cancer screening among a random sample of women from inner-city neighborhoods with high rates of cervical cancer mortality. Of 416 women interviewed, 30.3% reported hysterectomies; women with intact uteri (N = 290) are the subjects of this analysis. Over two-fifths (44.1%) reported not receiving adequate Pap testing during the previous 4 years. Compared with adequately screened women, they were more likely to be 45 years or older, have no medical insurance, report never having been to an obstetrician-gynecologist, recall never having been told by a medical provider how often to get a Pap test, rely on providers for adequate screening, report not seeking care as often as they think they should, have less knowledge of risk factors for cervical cancer, and believe that women should get Pap tests less than yearly. Separate models for younger and older women showed that these factors vary by age, demonstrating the need for interventions to be sensitive to age subgroups. These findings suggest that cancer control activities should place more emphasis on motivating women as well as influencing the health care delivery system to maximize reductions in cervical cancer.

Adolescent

Nicotine-produced antinociception in minimally deprived smokers and ex-smokers.

The antinociceptive effects of two different modes of nicotine administration were investigated using a within-subject design. Ten minimally-deprived, habitual smokers and fifteen ex-smokers were studied in separate experiments. Nicotine was delivered in research cigarettes and tobacco snuff. Pain was induced using the cold pressor test. Subjects in both experiments exhibited pain reduction after nicotine administration without changes in nicotine withdrawal. The results suggest that nicotine can produce physiological and psychological changes that are relevant to the reinforcement of smoking but are independent of the state of nicotine withdrawal.

Adult

Bilateral coronoid hyperplasia resulting in severe limitation of mandibular movement. Report of a case.

A case of bilateral coronoid hyperplasia with limitation of mandibular motion in a female patient has been presented. Her symptoms began to develop around the age of 44. We believe that this is the first case to be reported in a female. Also, in all other reported cases symptoms began to develop around the onset of puberty. The literature has been reviewed with specific reference to the etiology of bilateral coronoid hyperplasia. This case brings the total number of reported cases to twenty-two. We hope that if similar cases are identified in female patients the practitioners will report them promptly. Only in this way will we be in a better position to understand the etiology of bilateral coronoid hyperplasia with special reference to heredity.

Female

Effects of outpatient treatment for problem drinkers.

This study was designed to investigate the effects of treatment length restriction and follow-up interview style on the outcomes of male alcohol abusers in out-patient treatment. Subjects (N = 48) were randomly assigned to one of four independent groups based on the factorial combination of the two independent variables. Extensive pretreatment data were collected about subjects' drinking and related behaviors, and subjects were then scheduled for monthly interviews. Subjects were interviewed for 18 months postadmission concerning these same factors. Subjects' self-reports were compared with collateral reports, official records, and breath tests. Outcome results showed no effects of follow-up interview style or treatment length restriction on drinking behavior and employment outcomes. However, subjects' drinking behavior postadmission was considerably improved compared to their pretreatment ethanol consumption. Temporal analyses of the drinking behavior data showed that it was possible to predict drinking behavior, especially of the same type, within pretreatment and postadmission intervals. However, it was not possible to predict postadmission drinking from pretreatment drinking. Treatment implications of the findings are discussed.

Adolescent

Insulin-like peptides in the lobster Homarus americanus. I. Insulin immunoreactivity.

Experiments were conducted to determine if insulin-like peptides are present in the lobster Homarus americanus. Peptides were found that bind specifically to bovine insulin antibodies in a modified vertebrate radioimmunoassay. Extracts of whole hepatopancreas, gut, and hemolymph contained insulin immunoreactivity (IRI) concentrations of 67.5, 14.0, and 11.0 ng, respectively, per 700-g lobster. No insulin immunoreactivity was detected in neurosecretory cells of the eyestalk. The highest immunoreactivity was measured in the hepatopancreas, in the same fractions of eluate which contained the highest immunoreactivity when a bovine insulin standard was passed through the same chromatographic column.

Animals

Insulin-like peptides in the lobster Homarus americanus. III. No glucostatic role.

Lobsters contained insulin immunoreactivity ranging from 3.4 +/- 0.6 to 7.2 +/- 0.5 microU ml-1 hemolymph. Experimental results indicated that the hemolymph insulin immunoreactive peptides have no glucostatic function. With an increase in exogenous glucose in the hemolymph no increase in hemolymph immunoreactive insulin was observed. Also, injection of hepatopancreas extract did not increase the rate of glucose removal from the hemolymph.

Animals

Augmentation rib grafting to the inferior border of the atrophic edentulous mandible: a 5-year experience.

Inferior border rib grafting appears to be a useful procedure in providing bony augmentation for severely atrophic edentulous mandibles. Major advantages to the prosthodontic patient are that (1) remodeling and changes in the denture-bearing surfaces are minimal following surgery, (2) the interocclusal space is unaltered, (3) in nonunion body fractures occurring in severely atrophic mandibles, the ribs applied to the inferior-buccal and inferior-lingual aspects of the mandible hold the fragments in a much more favorable position, thus preventing superior elevation of the posterior segment and inferior displacement of the anterior segment, and (4) resorption rates seem acceptable. The patient should be informed of possible consequences. As with all preprosthetic special procedures, a psychosocial analysis may also be indicated.

Alveolar Ridge Augmentation

Handedness and spatial ability.

Data from a large-scale study of cognitive abilities were used to test the hypothesis that there are handedness-related differences in spatial visualization. The spatial factor score of the cognitive test battery provided a measure of spatial visualization. Analyses revealed a sex X handedness X ethnicity interaction on the spatial factor, and no significant handedness-related differences on verbal factor. In all ethnic groups strongly left-handed males had higher spatial scores than strongly right-handed males, whereas strongly left-handed females had lower spatial scores than strongly right-handed females. Among subjects of Japanese or Chinese ancestry, strongly left-handed subjects differed from ambidextrous subjects as well as from right-handed subjects, and these differences, too, were of opposite sign for males and females. It is suggested that the use of spatial ability measures which are relatively insensitive to differences in right hemisphere ability, as well as the failure to attend to degree of handedness, ethnicity, and particularly gender, may be responsible for the negative findings in this area of research.

Adolescent

The sex difference on one test of spatial visualization: a nontrivial difference.

Plomin and Foch's conclusion that sex differences in cognition account for very little of the total variability is challenged by demonstrating that, on a complex test of spatial visualization, the difference between males and females accounts for a quite substantial portion of the variability of the test scores. 2 measures of spatial visualization--the ETS Card Rotations test and the Shepard/Metzler Mental Rotations test--were administered to a large sample of college students. The Card Rotations test requires identification of fairly simple abstract forms after rotation within the plane; the Mental Rotations test requires identification of representations of more complex 3-dimensional figures after rotation in 3-dimensional space. Males scored significantly higher than females on both tests. Sex accounted for only 2% of the variance on the Card Rotations test but for 16% of the variance on the Mental Rotations test. Comparable sex differences on the Shepard/Metzler Mental Rotations test have also been found by other investigators.

Adolescent

Photoelastic stress analysis of hemimandibulectomy bone reconstruction devices.

The results presented show the relative importance of muscle force and occlusal resistance locations and prosthesis/hemimandible interface length. For the prosthesis design used, the addition of muscle function on the prosthesis side has little effect upon bone stress. However, occlusal resistance on the prosthesis side produces much more stress in the bone than other resistance positions. Stress produced by the shorter prosthesis is higher at the areas of bolt/bone interface than for the long prosthesis. However, superimposed inherent stress patterns somewhat obscured the comparison with longer prostheses.

Dental Stress Analysis

Withdrawal-like signs induced by a single administration of ethanol in mice that differ in ethanol sensitivity.

These experiments studied changes produced by a hypnotic dose of ethanol in the LS and SS lines of mice, which differ in ethanol sensitivity. In the first experiment, animals were injected either with ethanol or saline, and activity and seizure susceptibility measured 7-9 h later when blood levels of ethanol would have reached zero. Ethanol-treated mice of both genetic lines were less active in an open field test and more susceptible to clonic convulsions induced by flurothyl than saline-injected controls. There was no difference in the magnitude of these changes in the two lines. In the control condition SS (short-sleep) mice were more active than LS (long-sleep) mice, and more susceptible than LS mice to myoclonic but not to clonic seizures. The effect of the ethanol injection on body temperature was evaluated in separate groups of animals. LS mice showed a more pronounced hypothermia than SS mice when temperature was measured 2 h after injection. Six hours after injection, SS mice exhibited a small but statistically significant overshoot in temperature, after which they again became hypothermic with respect to controls; hyperthermia was not observed in LS animals.

Animals