MR imaging of growth recovery lines in fossil vertebrae.
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Biomedical subjects
Publications and source records attributed to B Rothschild.
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Reflex sympathetic dystrophy, causalgia, Sudeck's atrophy, shoulder-hand syndrome, and transient osteoporosis represent a spectrum of sympathetic disturbances which typically present with regional findings. They are often pauciarticular in distribution and uniquely sensitive to timely therapeutic intervention and to preventative measures. Clinical and radiologic appearances are quite characteristic. Thermographic examination provides a valuable tool for monitoring the therapeutic response. The major factor in therapeutic efficacy is aggressive physical therapy. Although therapeusis has been facilitated by a multitude of agents, therapeutic resistance is unfortunately the circumstance, when intervention is delayed.
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Lymphadenopathy, as a complication of gold therapy, appears to be an uncommon occurrence. Lymph node infarction has not been previously documented in this setting. The unique pathologic features in this case may reflect: a phenomenon specific to gold; early examination of the infarcted node; or underlying leukocytoclastic angiitis secondary to gold toxicity. Polymorphonuclear leukocytic infiltration of an infarcted lymph node has apparently not been previously reported.
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Significance of fibrinolysis in pathophysiology of progressive systemic sclerosis (PSS) has been the subject of much speculation. Renal disease in PSS was associated with significant depression of an inhibitor of fibrinolysis, antithrombin III (ATIII), independent of general disease activity. Association of ATIII depression with plasminogen consumption supports an active role for plasmin or another ATIII-inhibitable enzyme in the pathophysiology of renal disease in PSS, and may explain the thrombotic tendency and propensity for fibrin deposition.
Vasculitis is reviewed as a continuum of disease from asymptomatic to life-threatening. Therapeutic intervention predicated upon assessment of the significance of organ system involvement and the relative risks of the various forms of therapeutic intervention are discussed.
Some of the collagen-vascular diseases and overlap syndromes included are polymyosititis, systemic lupus erythematosus, scleroderma, Sjögren's syndrome, and Raynaud's phenomenon. Because diagnosis and treatment can be complicated, primary care physicians may want to seek experienced consultation.
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The purpose of this article is to present an assessment method, in conjunction with age-related normal values, for lumbar spinal range of motion. Lumbar flexion, lumbar extension, and right and left lateral flexion were measured on 172 subjects by a combination of goniometry and spinal distraction techniques. Normal values are given for six age groups; each group had a range of 10 years. The results demonstrate that a significant decrease in lumbar spinal range of motion is expected with increasing age. The interobserver reliability based on 17 subjects was substantial for the four measurements taken; coefficients ranged from +.76 to +1.0. The information may prove useful to the clinician as an improved method for assessing the lumbar spine.
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Equations describing plaque formation in soft agar have been based on certain simplifying assumptions, for which data are presented. The derived equations permit one to calculate (i) average plaque size as a function of the initial density of indicator cells (Do), (ii) the number of cells lysed per plaque as a function of Do, and (iii) the cumulative number of cells lysed at various stages of plaque development. The calculated values agree well with those determined experimentally.
Excretory urography is not an infallible diagnostic procedure and should not be relied upon exclusively. A normal study must never result in the rejection of additional data derived from history, physical examination and laboratory tests. Two case histories are presented to underscore this caveat. Excretory urography must be supplemented additional radiographic evaluations when the conventional study fails to completely explain the clinical situation.