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Biomedical subjects

B Pasquier

Publications and source records attributed to B Pasquier.

177 records · Page 10Linked to original sources

[Carcinoïd heart disease: clinical, light and electron microscopic study (author's transl)].

The authors report a clinical and pathological case of carcinoïd heart disease in a 70-years old man. The primary carcinoïd tumor was ileal with both hepatic and neighbouring lymph node metastases. The clinical history was dominated by a typical carcinoïd syndrom biologically confirmed and accompanied by a tricuspid insufficiency. An autopsy permitted to described with precision the topography and extent of the cardiac affection. The originality of this work is due to the ultrastructural study which has rarely been done. This study permitted us to make some clinical histopathological, histogenetic and pathogenetic comments.

Adolescent↗

[Renaut's bodies and familial neuropathy of the Dejerine-Sottas type. Apropos of 2 anatomo-clinical cases].

The authors report the pathological and clinical findings in two cases of familial Dejerine-Sottas neuropathy, including the peripheral nerve lesions of an unusual type producing extensive sub-perineural separation. In one case, there was onion bulb hypertrophy of the schwann layer and definite demyelinisation and above all, endoneural nodular structures known as Renaut bodies. The presence of Renaut bodies has not, to our knowledge, yet been reported in Dejerine-Sotta's disease. It is rare but well known during other neural diseases, which are often familial and in various pathological circumstances, such as syringomylia, diabetes and hypothyroidism. The fibroblastic origin of these structures has been proved. Their possible pathogenic role and their significance are still the object of discussion.

Adolescent↗

[Collar-stud tumour composed of combined neurilemmona and haemangioma elements. Clinicopathological study of one case with mediastinal and intraspinal localization (author's transl)].

A mediastinal and intraspinal collar-stud tumour in a 77 year-old-woman is reported. The orginality of this study comes from the histologic findings of a combined neurilemmoma and angioma. The authors also include a brief review of literature and clinicopathological and histogenetic comments, about these combined tumours.

Aged↗

[Detection of glial fibrillary acidic protein in central nervous tumors using an immunohistochemical method. Preliminary study of 33 cases (author's transl)].

Thirty-two cases of human central nervous tumor and one experimental glioma were studied in fixed paraffin or epon embedded tissues using the peroxidase-antiperoxidase method. The present study confirms the usefulness of immunohistochemical methods for the diagnostic evaluation of neuro-epithelial neoplasms. The authors also include some prognostic and histogenetic comments about glial tumors.

Glial Fibrillary Acidic Protein↗

[Hepatic lesions caused by vinyl chloride monomer in humans. Study of eight clinicopathological cases (author's transl)].

Six hepatic angiosarcomas, one hepatoma and one hepatic "fibrosis" with portal hypertension in patients chronically exposed to vinyl chloride monomer (VCM) are reported. The industrial methods of synthesis and current knowledge concerning the carcinogenic role of VCM are reviewed. Histogenetic and pathogenetic concepts of "fibrosis" and angiosarcomas of liver are exposed.

Adult↗

[A case of thalamic cavernous hemangioma in an infant].

The case reports an asymmetric, slowly increasing hydrocephalus with left leg monoplegia. The vascular origin of the tumor was suspected by CT scan and confirmed by surgery and the pathology analysis. These tumors are infrequent in childhood especially in this region. The surgical treatment before hemorrhagic complication permits to hope good results in the absence of malignancy.

Brain Neoplasms↗

[Capillary and cavernous hemangioma disclosed by painful amyotrophy of the thigh].

We report the case of an intramuscular cavernous and capillary hemangioma of the thigh revealed by pains evolving for 2 years and by an amyotrophy. After 21 months of investigation, the surgical excision and the histological examination only established the dia Thigh MRI. T1-weighted axial and sagittal sections with gadolinium infusion.

Adult↗