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Biomedical subjects

B P Moore

Publications and source records attributed to B P Moore.

At least 91 records · Page 5Linked to original sources

CPD in Canada.

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Blood Preservation↗

A 'new' high frequency antigen Era.

Three examples of an antibody defining a 'new' high frequency red blood cell antigen, Era, are described. Family studies show Era to be inherited, but the mode of inheritance may not be straightforward.

Blood Group Antigens↗

A "new" lectin for detection of T, Tn, and Th polyagglutination.

A lectin reacting with T, Tn, and Th polyagglutinable red blood cells was found in an extract from the seeds of Hibiscus sabdariffa (Sorrel). This lectin is thus a useful addition to those available for distinguishing various types of red blood cell polyagglutinability.

Blood Group Antigens↗

Trial of a combined test for the detection of HBsAg and anti-HBc.

A combined hepatitis test (Ausria/Core, Abbott Laboratories, Wiesbaden, West Germany) detects hepatitis B surface antigen by radioimmunoassay and antibody to the core antigen by enzyme immunoassay using a single bead. It was found to have comparable sensitivity to commercially available tests from the same manufacturer for each component. Reproducibility was satisfactory for both components. The combined test is simpler and cheaper to perform than two separate tests.

Hepatitis B↗

Comparison of a modified manual hexadimethrine bromide (Polybrene) and a low-ionic-strength solution antibody detection technique.

Manual hexadimethrine bromide (Polybrene) tests (Polybrene in low-ionic medium) were used in parallel with manual low-ionic-strength solution (LISS) procedures for the routine testing of patient samples referred to a general hospital blood bank. Of 5646 consecutive sera tested, 5167 (91.5%) did not react with either technique; 320 sera (5.7%) reacted in both methods. The Polybrene technique detected 63 antibodies which did not react in the LISS methods. One hundred sera did not react in the Polybrene test, but did react in the LISS methods. Sera showing discrepant results between the two methods were further tested in a reference laboratory. Polybrene tests appeared to be better in avoiding reactions due to clinically nonsignificant antibodies. The LISS methods, however, appeared to be more sensitive in detecting antibodies of potential clinical significance.

Blood Banks↗