Effect of growth & differentiation on distribution of arginase & arginine in rat tissues.
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Aging↗
Biomedical subjects
B Nagarajan
Publications and source records attributed to B Nagarajan.
A specific & sensitive method for estimation of L-arginine in body fluids & tissues.
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Animals↗
Effect of various therapeutic treatments on polyamine contents in experimental fibrosarcoma.
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Animals↗
A simple method for the conversion of arginine to ornithine & citrulline.
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Animals↗
Changes in polyamine content during hepatocarcinogenesis.
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Animals↗
Inducibility of alkaline phosphatase in HeLa cells by hydrocortisone.
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Alkaline Phosphatase↗
In vitro drug sensitivity test on a chemically induced fibrosarcoma in mice.
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Animals↗
A rapid method for the production of fibrosarcoma in rats and the effect of BCG administration.
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Animals↗
Some aspects of electrical properties of normal liver and malignant hepatoma.
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Carcinoma, Hepatocellular↗
The distribution of 59-Fe in albino rats after intravenous administration in the ionic or chelated form.
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Animals↗
A prognostic insight on in vivo expression of interleukin-6 in uterine cervical cancer.
Interleukin-6 (IL-6) is a multifunctional cytokine with a growth promoting role in cancers. In an attempt to evaluate the prognostic significance of IL-6, we have studied the localization of this cytokine by immunohistochemical methods in normal, premalignant, and invasive cervical cancers. We stained frozen sections with a monoclonal antibody specific for human IL-6 and demonstrated that tumor cells show positivity with high intensity and stromal cells with moderate intensity. T cells and macrophages, components of the stroma that secrete IL-6, were also looked at. While T cells showed a weak positive correlation, CD68-positive macrophages showed significant positive correlation (P < 0.05) with IL-6 positivity in stroma. The patients were followed up for 40 months after treatment with standard radiotherapy regimen and showed residual tumor where pretreatment IL-6 levels were high. Our results suggest its possible candidature as a prognostic indicator of cervical cancer.
Adult↗