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Biomedical subjects

B Marincek

Publications and source records attributed to B Marincek.

At least 109 records · Page 6Linked to original sources

[Sclerosing mesenteritis].

A patient with an inflammatory fibrous tumor of the mesenteric fat tissue is reported. Clinical signs were epigastric pain, weight loss and palpable abdominal mass. diagnosis was by abdominal CT and surgical biopsy. The histological feature was diffuse fibrosis. Isolated mesenteric fibrosis is a rare variety of systemic idiopathic fibrosis, a disease entity including fibrosis of the retroperitoneum and other sites. Among possible etiological factors an autoimmune origin, drugs (methysergide) and lymphatic obstruction are discussed. Our patient had congenital hypoplasia of the lymphatic drainage system of the legs. She recovered rapidly and spontaneously and the tumor regressed on CT. Fatal courses are exceptional and medical therapy usually is not required.

Adipose Tissue↗

[Whole body magnetic resonance imaging].

Magnetic resonance imaging (MRI) has a growing number of applications in the whole body area. Its role cannot be properly considered without comparing it to the diagnostic capabilities and availability of sonography and the high standard of newest-generation CT. MRI is an accepted diagnostic modality for diseases involving the pelvis and the musculoskeletal system. It is equal or superior to other modalities in examination of the neck, the cardiovascular system, the upper abdomen and the retroperitoneum.

Bone Diseases↗

[CT and MRT following liver transplantation].

The potential technical complications after liver transplantation are numerous. CT is most useful in the evaluation of the hepatic parenchyma and in the identification of perihepatic fluid collections. CT provides complementary data when the sonographic findings in cases with suspected vascular or biliary complications are unclear. The value of MRI in the evaluation of liver transplants has not yet been fully determined. In patients with complex venous hemodynamics MRI can add useful information.

Humans↗

[Radiologic diagnosis following pancreas transplantation].

Technical complications are relatively common after pancreatic transplantation, and most require radiological evaluation. Ultrasonography and computed tomography are helpful in the identification of peripancreatic and intra-abdominal fluid collections. Sterile fluid collections can be effectively treated by percutaneous catheter drainage, whereas most intra-abdominal infections require surgical intervention. Angiography is performed primarily for diagnosis of vascular thrombosis. Recent results suggest that magnetic resonance imaging may be a useful non-invasive method for the detection of pancreatic transplant rejection. Further imaging studies are needed to better define the development of progressive fibrotic atrophy in long-term functioning pancreatic transplants.

Humans↗

[Computed tomography evaluation of kidney diseases].

The primary role of renal computed tomography (CT) is to determine the extent of a complicated cystic or solid mass lesion. CT is indicated if the nature of a mass detected on urography cannot be determined by sonography and if sonography fails to define the perirenal or pararenal extension of a lesion. When urographic findings suggest a pathologic entity other than a simple cyst (calcifications or fat in a mass lesion, destruction of the collecting system), CT may be performed subsequent to urography.

Humans↗

Hepatic vein occlusion: morphologic features on computed tomography and ultrasonography.

Hepatic vein occlusion causes morphologic changes that can be demonstrated by computed tomography (CT) and ultrasound. In this study the imaging findings of acute, subacute, and chronic occlusion of the hepatic veins were analyzed retrospectively in 9 patients and correlated with the histopathologic changes. The CT findings were focal or scattered hypodense parenchymal lesions of the liver before and a patchy enhancement after intravenous bolus injection of contrast material. In none of the cases could the hepatic veins be identified. Hepatomegaly with relative enlargement of the caudate lobe was almost always observed. Ultrasonography demonstrated solid material within the major hepatic veins, intrahepatic venous collaterals, and focal parenchymal lesions, which varied with the stage of the disease: a hypoechogenic area was observed in acute hepatic vein thrombosis with subsequent hemorrhagic infarction; hyperechogenic lesions corresponded with fibrotic zones in chronic disease. Ascites was shown by both methods in all patients.

Adult↗

[Computed tomography of an aortoiliac aneurysm with ureteral stenosis].

10 patients with uni- or bilateral ureteral stenosis due to an aortoiliac aneurysm were evaluated by computed tomography. In 6 patients the complicating ureteral stenosis was caused by an inflammatory aneurysm, in 3 patients by an arteriosclerotic aneurysm, and in 1 patient by a secondary expanding aneurysm of the internal iliac artery following aortofemoral reconstruction. CT allowed non-invasively to document the association between ureteral stenosis and aneurysm. Post-operative follow-up CT studies of the 6 patients with an inflammatory aneurysm revealed a time dependent regression or complete disappearance of the perivascular fibrosis.

Aged↗

CT appearance of impaired lymphatic drainage in liver transplants.

Early postoperative CT scans of three patients who had undergone liver transplantation show hypodense areas surrounding the portal venous system and to a lesser extent the intrahepatic inferior vena cava. These changes were considered to represent dilated lymphatic vessels caused by impaired lymphatic drainage of the transplant after total interruption of the lymphatic vessels at surgery. This hypothesis was tested in three piglets after complete surgical interruption of the lymphatic vessels of the liver. Results of histologic examinations and an additional long-term follow-up CT study in one patient suggest that hypodense periportal and pericaval areas are a reversible CT finding in liver transplants caused by lymph stasis.

Adult↗

Calculated T1 and T2 MR images and 31P MR spectra in rabbit thigh V2 carcinoma to monitor the effect of steroid administration.

T1 and T2 proton relaxation times in six rabbit thigh V2 carcinomas were obtained from regions of interest on calculated MR images at 2.35 tesla before and after steroid administration. Mean T1 and T2 values of viable tumor tissue decreased after steroid administration, consistent with decreased tissue water content. After steroid withdrawal, T1 and T2 values returned toward baseline. Relaxation times of peritumoral muscle tissue and normal contralateral thigh muscle essentially remained unchanged. In a separate experiment, six rabbit thigh V2 carcinomas were monitored before and after steroids by 31P spectroscopy using a surface coil. No substantial steroid-related changes were recognizable. A fall of the ratio of phosphocreatine to inorganic phosphate and a signal increase from phosphomonoester and phosphodiester compounds were observed during various stages of tumor growth. Analysis of 31P spectra changes and sequential measurements of relaxation times may prove valuable for assessment of tumor growth and therapeutic response in diagnostic oncology.

Animals↗

Roentgenologic assessment of initial relapse in stage I-III Hodgkin's disease.

The role of conventional radiography and CT in the assessment of initial thoracic and abdominal relapse in stage I-III Hodgkin's disease has been analysed in 43 patients. Lymph node involvement was seen in all patients, extranodal involvement in fifteen. The presence of thoracic relapse had been detected essentially by chest X-ray, but CT proved to be useful for definition of the topographic-anatomic extent of tumour manifestation. In the abdomen the presence and extent of any relapsing disease had been demonstrated mainly by CT. Additional lymphangiography was necessary in only one patient.

Abdominal Neoplasms↗

[Thoracic aortic aneurysms].

The various pathological types of aneurysm are reviewed and their natural history discussed in relation to morphology, etiology and site of the aneurysm. For diagnostic purposes, computed tomography is a reliable method in the detection of aortic aneurysm; for evaluation of the ascending segment, ultrasonography may also be considered a useful procedure. The two non-invasive methods are particularly valuable in monitoring patients with thoracic aneurysms not (yet) suitable for surgery. In the light of the literature and our own experience, practical guidelines for adequate treatment of non-dissecting aneurysms of the thoracic aorta are elaborated with respect to aneurysm site. In patients with anulo-aortic ectasia, surgical treatment is clearly indicated in the presence of typical Marfan syndrome and in cases showing a demonstrable increase of aneurysm dilatation and/or of aortic regurgitation (hospital mortality 5% in our experience); irrespective of these criteria, surgery should be considered if the echocardiographic root diameter is greater than 6 cm. Replacement of the aortic arch carries a high surgical risk and is suggested for patients suffering from symptoms such as pain or compression of adjacent tissues; in asymptomatic patients, arch resection is scarcely advisable unless the aneurysm is of luetic origin. For aneurysms of the descending aorta, the operative indication will also be related to clinical symptoms as well as to aneurysm expansion and growth; in asymptomatic subjects, surgery is recommended in the presence of a circumscribed posttraumatic false aneurysm, the operative risk being very low in this patient group. In cases with suspected aortic dissection, computed tomography is considered to be the primary diagnostic procedure. Angiography may be mandatory only for those few presurgical candidates who require accurate assessment of aortic valvular regurgitation and determination of peripheral organ perfusion. The extremely unfavourable natural history of acute aortic dissection (50% survival after 48 hours following onset of symptoms) clearly calls for immediate operative treatment in high-risk patients, that is in subjects with acute ascending aortic dissection (hospital mortality 28% in our series). The better prognosis of descending aortic dissection suggests that in these cases conservative hypotensive therapy is the treatment of choice; surgical intervention in type B acute dissection is indicated only if occlusion of a major aortic branch occurs or if impending rupture of the dissecting hematoma becomes evident.(ABSTRACT TRUNCATED AT 400 WORDS)

Acute Disease↗

[Computer tomography in primary soft tissue tumors].

Computed tomography was performed in 37 patients with primary soft tissue tumours (24 malignant and 13 benign lesions). Except for lipomas it was not possible to relate attenuation values to histologic type or grade of malignancy. Major advantages with CT include the ability to demonstrate infiltration of surrounding structures and to determine tumour size. There is a risk of overestimating the size of malignant tumours because of peritumoural edema.

Abdominal Muscles↗

[Computed tomographic classification of acetabular fractures].

The contribution of computed tomography (CT) in classifying acetabular fractures was analysed retrospectively in 33 cases. CT and plain radiography classification agreed in 27 cases (82%). CT revealed more extensive fractures in 6 patients (thereof 5 patients with associated fractures). In 10 patients (thereof 9 patients with associated fractures) CT showed intraarticular fragments; radiographically intraarticular fragments were seen only in 2 patients and suspected in 4. CT is of considerable aid in defining the fracture pattern. It should be used mainly in patients with radiographically difficult interpretable associated fractures in order to assess preoperatively the weight-bearing part of the acetabulum, the degree of displacement and the presence of intraarticular fragments.

Acetabulum↗

[Computed tomography of chondrogenic tumors].

The computed tomography (CT) morphology of chondrogenic tumors and the utility of CT in their diagnostic work-up is presented on the basis of 19 cases. CT provided unique informations regarding definition of tumor extent and tumor relationship to adjacent structures particularly in the axial skeleton. CT has diminished the indications for angiography in chondrogenic tumors.

Acetabulum↗

[Computer tomography of mycotic aortic aneurysm].

The CT findings in 2 patients with mycotic aortic aneurysms are presented. CT was helpful in establishing the diagnosis by detecting the presence of aneurysms surrounded by an abscess and reactive enlargement of the lymph nodes. CT should be the first investigation for patients with suspected aortic aneurysms and with fever of unknown origin.

Aneurysm, Infected↗