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Biomedical subjects

B Luther

Publications and source records attributed to B Luther.

At least 91 records · Page 5Linked to original sources

[Surgical correction of atypical aortic coarctation with hypertension].

Atypically localised coarctation of the aorta is one of the very rare pathological findings. Hypertension of unknown aetiology, atypical vascular sounds, and symptoms of collateral circulation are indicative for diagnosis. Vascular surgery is justified in any case by the juvenile age of the patients concerned and by poor quoad vitam prognosis. Generally, surgical intervention should be undertaken with patients between eight and 14 years of age. Surgical methods and results are reported.

Adolescent↗

[Brain protection in the surgical reconstruction of the supra-aortic arteries].

The importance of brain protection in surgical handling of supra-aortic arteries may be derived from the specific nature of cerebral blood flow and from the pathophysiology of damaged cerebral vessels. There is a wide range of special protective methods which have proved to be effective, including strict observance of established rules on surgical indication and tactics, maintenance of circulatory homoeostasis, heparinisation, and use of an intra-luminal shunt. Results obtained from operations on 486 patients for occlusion of supra-aortic arteries are discussed, with particular emphasis being laid on the need for intra-operative EEG monitoring. Reference is also made to measures of brain protection in the postoperative phase.

Aged↗

[History of surgery at Berlin University].

The author reports on the development of the surgical hospitals "Charité" and "Klinikum Ziegelstrasse" in Berlin during the last 260 years. Special attention is given to the merits of their leading surgeons.

Berlin↗

[Sexual function disorders after vascular reconstruction in the aortoiliac region].

100 male patients who had undergone aorto-iliac surgery were asked by a questionnaire concerning their sexual life. Stenoses or obstructions of the iliac arteries preoperatively demonstrated in 70% could be shown to be connected with sexual disorders, which increased after operation. Especially in patients of younger age the reperfusion of the internal iliac arteries should be taken into consideration.

Adult↗

[Clinico-experimental studies on blood viscosity].

After their preponderated surgical treatment by 144 patients have been taken the blood-viscosity in dependence of some physiological and pathophysiological parameters after infusion of infucoll 6%. We have used for these compared examinations the rheo-viscometer after Höppler. So we succeeded in proving the relationship between increased blood-viscosity, maligne tumour sufferings, and illness of the respiratory system. The results of the infucoll preparation are - with regard to the coagulation, hindrance of thrombocyte aggregations, and viscosity reduction - to qualify as discreet, showing more regulating character.

Adolescent↗

Immunopathologic aspects in human onchocercal lymphadenitis.

Lymph nodes (LN) from 50 patients with generalized onchocerciasis with or without diethylcarbamazine treatment and LN of patients with untreated localized onchocerciasis were studied. Light and electron microscopic examinations and immunostaining (PAP) were performed. In both forms of the disease the majority of microfilariae were degenerated and surrounded either by eosinophils or macrophages. In addition increased number of mast cells and plasma cells was observed. A direct contact between eosinophils and microfilariae, degranulation of eosinophils and free eosinophil granules in the electron dense material around the degenerating microfilariae were registered. The majority of plasma cells produced IgE or IgG. A positive staining for IgE was also present on the surface of mast cells. An extensive hyperplasia of the follicles was a characteristic feature in localized as well as treated generalized onchocerciasis. After anti-IgE staining a heavy intercellular deposition suggesting trapping of immune complexes by dendritic reticular cells developed in the light parts of the germinal centres. Not seldom, IgE producing blast cells were found in the follicles.

Diethylcarbamazine↗

[Results of and experience with immunotherapy in children with asthma or allergic rhinitis (author's transl)].

Specific hyposensitization in 165 children with inhalant allergy was successful in 82.4%. Children with pollen-allergy showed statistically better results than those with other inhalant-allergies. In the latter group, the failure rate was significantly higher when polyvalent antigen-combinations were used. Age, and duration of the allergic disorder before therapy apparently have no significant influence on the therapeutic success. Children hyposensitized for more than one or two years achieved significantly better short-term results. Patients with atopic dermatitis showed worse results in both groups. Where there is no success after one year of therapy, antigen-determinations should be controlled by repeated cutaneous-vascular tests. In the non-pollen-allergies the prevalent antigen should be determined by provocation-tests. Longterm results after hyposensitization are less favourable than those shortly after a therapeutic course. Three years after discontinuation of therapy success diminished by 35.7%, the recurrence rate was higher in the 1st year than after 2 or 3 years. Frequent local and systemic adverse reactions demand a high responsibility of the physician performing the hyposensitization regimen. In pharmaceutical brochures up to 10,000 PNU are recommended, but this may result in dangerous overdoses.

Adolescent↗

[The function of thrombocytes by means of Infukoll 6% for thrombembolia prophylaxis].

The effect of Infukoll 6% was observed in 58 surgical patients during 3 respectively 14 days in the postoperative phase by means of the Breddin and the Borntest. Infukoll showed a small effect as an inhibitor of the thrombocyte agglutination and for the regulation of the thrombocyte level in blood. The main effect lies in the rheological sector.

Dextrans↗