Search PubMed⌕ Search

Biomedical subjects

B Law

Publications and source records attributed to B Law.

93 records · Page 6Linked to original sources
PubMedDate not supplied

A novel 125I radioimmunoassay for the analysis of delta 9-tetrahydrocannabinol and its metabolites in human body fluids.

A cannabinoid radioimmunoassay (RIA) that detects some of the major delta 9-THC metabolites is developed and evaluated for use in forensic science. It incorporates a novel 125I radiotracer, is sensitive, reliable, relatively quick, and simple to use. The RIA uses a commercially available antiserum and detects a number of cannabinoid metabolites, including delta 9-THC-11-oic acid and its glucuronide conjugate in biological fluids. The method was successfully applied to the analysis of blood and urine samples submitted for forensic analysis.

Body Fluids↗
PubMedDate not supplied

Confirmation of cannabis use by the analysis of delta 9-tetrahydrocannabinol metabolites in blood and urine by combined HPLC and RIA.

Cannabis use is confirmed through the analysis of blood and urine using combined high-performance liquid chromatography/radioimmunoassay to detect delta 9-THC-11-oic acid and its O-ester glucuronide (the major delta 9-THC metabolites). The method is sensitive and specific and will allow the complete analysis of at least six samples per day. It has been successfully applied to the analysis of samples submitted for forensic analysis and, in combination with a previously described radioimmunoassay, offers a useful approach to routine toxicological analysis of cannabinoid metabolites.

Chromatography, High Pressure Liquid↗