Search PubMed⌕ Search

Biomedical subjects

B L Carter

Publications and source records attributed to B L Carter.

At least 145 records · Page 8Linked to original sources

Computed body tomography: how useful is it?

Computed tomography (CT) of the body is becoming as well established a diagnostic procedure as CT of the head, often yielding information not available by other techniques and sparing patients unnecessary surgery. To take proper advantage of CT, physicians should understand the full potential and practical applications of this new technique. Properly used, it can expedite diagnosis and decrease the number of procedures needed per patient.

Biliary Tract Diseases↗

Computed tomography in diagnosis of abdominal masses in infancy and childhood. Comparison with excretory urography.

Computed tomography (CT) of the abdomen and pelvis was performed in 26 instances of suspected mass in 24 infants and children. The information obtained was compared to that of standard abdominal radiography and excretory urography (IVP). Results were analyzed prospectively. CT was able to detect and define masses more precisely than abdominal radiography and IVP. The information obtained by CT, in a single noninvasive examination emitting minimal ionising radiation, seems comparable to that offered by a combination of multiple radiological and other imaging procedures. It is conceivable that with accumulating experience and further technological improvement CT may become an excellent screening procedure in the investigation of abdominal and pelvic masses. The high cost of CT scanning may be offset by the benefits cited.

Abdominal Neoplasms↗

Mediastinal lipomatosis. CT confirmation of a normal variant.

Mediastinal lipomatosis is a common benign cause of mediastinal widening. While it may be associated with exogenous obesity, steroid ingestion, or Cushing's syndrome, these factors often are not present. Evaluation of the mediastinum by CT should be the initial diagnostic study in the work-up of patients with abnormalities of the mediastinal contour; indeed, in many cases it can eliminate the need for other procedures.

Adult↗

Effects of temperature and nutritional conditions on the mitotic cell cycle of Saccharomyces cerevisiae.

Yeast cells were cultivated at different growth rates in a chemostat by alterations in the flow of the limiting nutrient glucose and in batch cultures where variations in growth rate were achieved by alterations in the composition of nutrients. It was observed that the stage in the cycle at which S-phase was completed varied with growth rate. The faster the growth rate, the earlier the stage in the cycle in which completion of S-phase occurred. When stage in the cycle is converted into time before division it was observed that the time from completion of S-phase to cell division varied only slightly with growth rate except at extremely slow growth rates. Expansion of cell cycle transit time as the growth rate was slowed was achieved primarily by an expansion in time of the period from division to the completion of S-phase. In contrast, when cells were grown at different rates by alterations in the temperature of cultivation, completion of S-phase occurred at approximately the same stage in the cell cycle at all growth rates.

Cell Cycle↗

Value of computed tomography in radiotherapy of lung cancer.

The effectiveness of CT scanning in radiotherapeutic treatment planning was evaluated in 32 patients with bronchogenic carcinoma. CT of the chest in pretreatment evaluation of these patients supplemented conventional clinical and radiographic patients supplemented conventional clinical and radiographic studies, resulting in (1) more clear delineation of tumor extent in 24 patients (75%); (2) change in assessment of the size of lesions in 14 patients (43%); (3) change of disease stage in 13 (40%); (4) demonstration of inadequacy of treatment plan in nine (28%); and (5) changes in the volume of normal tissue irradiated in 14 (40%). CT scan data was judged essential for treatment planning in 17 patients studied (53%). Unsuspected areas of tumor involvement were seen in 21 patients (65%). Use of the CT scan as a patient contour for radiotherapy treatment planning of lung cancer and alternative techniques are discussed.

Adult↗

Contribution of computed tomography to the treatment of lymphomas.

The effectiveness of computed body tomography (CT) in the workup, treatment planning, and follow-up of 38 patients with Hodgkin's disease and 59 with non-Hodgkin's lymphoma was analyzed. CT scanning can frequently define lymphoma in the retroperitoneum, and occasionally in mesenteric lymph nodes, spleen, and liver. These data are useful for staging, for radiotherapy treatment planning, and in monitoring response to radiotherapy or chemotherapy. CT was found to be particularly useful in patients with large mediastinal masses. Analysis of patterns of intrathoracic spread allowed modification of treatment techniques in 60% of patients with spread along the chest wall, in order to reduce the volume of normal tissue irradiated, while obtaining adequate dose distributions within the tumor volume. It is anticipated that chest CT scanning in lymphoma patients will lead to improved tumor control and reduction of radiation complications.

Adult↗

Use of body scanner in radiotherapy treatment planning.

CT body scans obtained on 98 patients before, during, and after radiotherapy were evaluated for their utility in radiotherapy treatment planning and in follow-up after radiotherapy. Twenty-two patients were studied after irradiation. Four received additional treatment, and continuing or planned treatment was withheld from another four on the basis of CT data. Tumor extent was clearly delineated on CT scan in 48/76 cases (63%), suggestive in 25/76 (33%), and not seen in only three (4%). Utilizing CT data relative to all other available tests, in 75 patients, total treatment volume was altered in 34 (45%), tumor coverage was marginal or inadequate in 35 (47%), and volume of normal tissue irradiated was changed in 34 (45%). CT scan data was judged essential for treatment planning in 41, or 55%, of patients studied. Unsuspected areas of tumor involvement were seen in 32 of 75 cases (43%). Use of the CT scan as a patient contour for radiotherapy treatment planning and alternative techniques for inputting the CT data to treatment planning computers are discussed. A simple inexpensive device to accomplish this is described. Speculations are made regarding the impact of CT scanners on transverse axial tomography units and treatment simulators as well as the potential application of the technique in brachytherapy dose computation.

Abdominal Neoplasms↗

Computed tomography of the skull base.

By applying a wide window to computed tomography (CT) images, excellent detail of the skull base has been obtained. This technique has been apllied to lesions involving the sellar, parasellar, sphenoid wing, petrous bone, clival, and foramen magnum regions. Thus, CT has proved to have an additional dimension in the delineation of pathology.

Humans↗

Neck and mediastinal angiography by computed tomography scan.

CT scanning of the neck and upper mediastinum is a valuable tool in the differential diagnosis of soft-tissue tumors. Visualization of the major vessels in the neck, which aids in the study, can be accomplished by a rapid intravenous drip infusion technique during the actual scanning, a new approach to contrast enhancement.

Angiography↗

Computed tomography in spinal dysraphism.

Computed tomography of the spine has been used to evaluate patients with spinal dysraphism. With this technique, the nature of soft-tissue masses can often be correctly diagnosed and the underlying bony anomalies clarified.

Adult↗

Computed coronal tomography.

A method for obtaining coronal scans of the cranium is described in which a scanner with a tilting gantry is used. Computed coronal tomography is especially useful in the high convexity area and in the suprasellar and foramen magnum regions.

Computers↗

Computed tomography of the spinal canal.

The value of computed tomography (CT) in cases of spinal dysraphism, spinal canal narrowing and widening, and spinal bony abnormalities is discussed. With further experience, CT may become a valuable modality for the diagnosis of spinal diseases.

Humans↗

Unusual pelvic masses: a comparison of computed tomographic scanning and ultrasonography.

Four unusual pelvic masses, studied by CT and gray scale ultrasonography, demonstrate the comparative values of these modalities for this area of the body. In each instance a significant contribution to the diagnosis was made by one or both techniques. The ultrasound study provides a somewhat better differentiation of solid from cystic lesions, but the CT scan denotes to best advantage the anatomy of the area, and provides a means of viewing bone as well as soft tissue detail.

Adult↗