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Biomedical subjects

B Kleinteich

Publications and source records attributed to B Kleinteich.

At least 37 records · Page 2Linked to original sources

Excretory urography as a screening method for abnormalities of the upper urinary tract in asymptomatic boys with undescended testicles.

Congenital dystopic testicles frequently occur jointly with abnormalities of the kidneys and the system of draining urinary ducts. A series of 100 asymptomatic boys has been studied by intravenous excretory urography after having undergone orchiopexy for retained testes. All children were clinically non-suspect and there was no history of urinary tract malformation. The investigations brought to light 7 major and 9 minor abnormalities. However, the authors do not recommend the use of intravenous urography as a routine procedure in all children with undescended testicles. The indications of the diagnostic procedure must be limited.

Adolescent↗

[The normal growth of the testis in the children and juveniles (author's transl)].

The volume of the testis in a group of 1,052 children and juveniles (age 5.0 - 17.9 years) chosen randomly has been calculated after measuring the length and cross section by sliding rule. This method is advised to be used routinely in the clinical investigations due to small error. Author's cases which showed only small but objective errors in the measurement give a non-linear functional regression as showed in the tabulated data. Those normal values give the possibility of carrying statistical comparative studies with cases of diseased testis.

Adolescent↗

[Sexual development of boys, treated surgically for dystopia of testicles (author's transl)].

A clinical follow-up examination was made in a group of 208 children and adolescents who had undergone surgical treatment for congenital cryptorchid testis (unilateral or bilateral) between 2 and 10 years before. The puberal growth and maturing process of the primary and secondary sex characteristics of this morbidity group was compared to that of normal juveniles. The examination was made according to clinical criteria: length and circumference of the penis, volume of testes, general development of the genitals, pubic hair. Compared to normal juveniles, the genital development of the children and adolescents of the follow-up examinations series was retarded.

Adolescent↗

[Testosterone reserve capacity in prepubertal and juvenile testes after sugery for undescended testis].

Tests testosterone reserve capacity of 6--15 year-old boys was estimated after operative correction of testicular maldescensus by a maximal stimulation test. Subnormal plasma testosterone levels were found in only 2 out of 14 patients with bilateral and 4 with unilateral orchidopexy. Prepubertal boys with unilateral anorchia had normal basal testosterone values and a normal testosterone rise after stimulation. In prepubertal boys with bilateral testes atrophy there was observed a diminished rise after stimulation. The basal testosterone levels were normal. The testosterone basal levels of pubertal boys with unilateral anorchia or bilateral atrophy were subnormal and the stimuation of testosterone production was reduced. The testicular volume of patients without atrophy or anorchia after orchidopexy was normal in prepuberty. During puberta a progressive relative decrease of the testicular volume was observed as compared to normal development. In conclusion, the results demonstrate that the endocrine function in most patients with unilateral or bilateral orchidopexy is in the normal range--a regular puberty can be expected.

Adolescent↗

[Evaluation of congenital-cryptorchid testicles after surgical treatment (author's transl)].

The volume of 271 congenital-cryptorchid testicles which were subject to surgical treatment was compared with that of 128 descended testicles of patients of the same age. Undescended testicles, also after successful surgical treatment, remain smaller on volume than descended ones. By means of the hitting method of the point counting technique the proportion of all seminiferous tubules in the total volume of one gonad can be calculated. The seminiferous tubules of congenital-cryptorchid testicles, also after intrascrotal replacement, maintain an essentially smaller proportion concerning the total volume as in descended testicles. Among the numerous methods of surgical treatment preference must be given to those which are especially favourable to the parenchyma.

Adolescent↗

[Studies on the growth of the width in seminiferous tubules of eutopic and congenitally dystopic testes in children and adolescents].

The average diameter of the seminiferous tubules is to be regarded as a criterion for the estimation of the morphological value of testicles. By means of 89 autoptically got preparations of regularly descended testicles the breadth-growth of the tubules depending on age in children was judged. Of 55 untreated congenital dystopic testicles morphometric determinations of the diameters of the seminiferous tubules were performed. At the same time 79 unilaterally and 78 bilaterally operatively dislocated, congenital dystopic testicles and 78 contralateral eutopic gonades were evaluated. The average diameter of the tubule of untreated dystopic testicles is significantly (p less than 0.001) smaller than the diameter of the orthotopic gonades corresponding to age. The average diameter of the tubule of operatively dislocated congenital dystopic testicles is, however, larger than the diameter of the untreated gonades corresponding to age. The earlier the treatment of congenital dystopic testicles is performed the larger are the chances of a development of the tubules corresponding to age.

Adolescent↗

[Length-growth of seminiferous tubules of untreated and as surgically displaced, congenitallydystopic testes in children and adolescents].

The total length of the seminiferous tubules of congenital dystopic testicles was calculated from bioptical preparations. 55 untreated testicles, 79 unilaterally and 78 bilaterally operatively displaced testicles as well as 78 contralaterally eutopic testicles were evaluated. During the whole prepuberal phase of life in the congenital dystopic testicles a nearly continuous growth of the length of the seminiferous tubules takes place. The total length of the intrascrotally displaced testicles is larger than the length of untreated testicles corresponding to age. After the operative correction of the position of congenital dystopic testicles an acceleration of the growth of the length of the tubule begins.

Biopsy↗