Search PubMed⌕ Search

Biomedical subjects

B Husum

Publications and source records attributed to B Husum.

78 records · Page 5Linked to original sources
PubMed1978

Arterial dominance in the hand.

Arterial pressure was measured simultaneously in the thumb and in the contralateral arm using strain-gauge plethysmography in 100 healthy persons aged 13--43 yr, before and after compression of the radial or the ulnar artery. The radial and ulnar pulses were palpable in all instances. In 29 (14.5%) hands compression of either artery did not reduce the thumb pressure. In 152 (76%) occlusion of the radial artery caused a decrease of more than 10 mm Hg, but never to less than 40 mm Hg. In 91 (45.5%) occlusion of the ulnar artery reduced thumb pressure, on three occasions to less than 40 mm Hg. Radial dominance was shown in 110 hands (55.0%), 24 (12.0%) showed ulnar dominance and in 66 (33.0%) neither vessel dominated.

Adolescent↗
PubMedDate not supplied

SCE in lymphocytes of patients treated with single, large doses of diazepam.

When using the SCE test for evaluation of exposure in vivo to potential mutagens/carcinogens, it is necessary to consider possible confounding factors. In studies of possible mutagenic effects of pharmacological treatment the effect of concomitant administration of other agents such as sedatives may have to be considered. In order to assess whether diazepam per se influences SCE we have examined SCE in peripheral lymphocytes in 34 persons before and after oral administration of a single large dose of diazepam. 18 men and 16 women undergoing minor surgery of the hand received diazepam 0.2 mg kg-1 body weight orally on the day of operation, and venous blood samples were drawn on the day before the operation and again 2-5 h after the administration of diazepam. Both within cigarette smokers and non-smokers there was no statistically significant change of SCE following diazepam. It was concluded that there was no indication, from the SCE test, of an immediate mutagenic effect of a single large dose of diazepam and that such medication is not a confounding factor in studies by the SCE test.

Adolescent↗
PubMedDate not supplied

Blood pressure in the great toe with simulated occlusion of the dorsalis pedis artery.

Blood pressure was measured in both great toes using strain-gauge plethysmography in 100 healthy persons aged 18 to 43 before and during successive compression of the dorsalis pedis artery, the posterior tibial artery, and both arteries at the same time. In 54 (27 percent) of 200 feet, successive compression of the dorsalis pedis and the posterior tibial arteries produced no decrease in pressure in the great toe. In 47 of the feet, toe pressure decreased significantly only after compression of the posterior tibial artery, and in 65 of the feet toe pressure decreased significantly only after compression of the dorsalis pedis artery. In 34 of the feet, toe pressure decreased significantly after compression of each of the arteries. Thus in 99 (50 percent) of 200 feet, compression of the dorsalis pedis artery decreased the pressure in the great toe significantly, and in 4 feet the pressure decreased below 40 mm Hg. When both arteries were simultaneously compressed, 69 feet showed detectable blood pressure in the great toe. Attempts to evaluate adequacy of collateral circulation by pressure blanching of the great toe prior to artery compression and then observing capillary refilling time upon release of toe compression proved unreliable.

Adolescent↗