Biomedical subjects

B Hoffmeister

Publications and source records attributed to B Hoffmeister.

At least 55 records · Page 3Linked to original sources

PubMed1989

DNA grading of oral squamous carcinomas. A preliminary report.

The prognostic validity of the DNA-malignancy-grade (DNA-MG), ranging on a continuous scale from 0.00 to 3.00 was tested in a preliminary study on 7 patients with oral squamous cell carcinomas. Monolayer smears were prepared after a cell separation procedure from paraffin-embedded surgical tumor specimens. Feulgen staining was performed automatically in a modified Shandon staining machine. A TV image analysis system with an automatic microscope (TAS plus, Leitz, FRG) was used for DNA measurements. The DNA-MG revealed a strong correlation with the patients prognosis. 3 patients who died after having a tumor relapse (mean survival = 10 months) had DNA grades greater than 1.40, whereas patients who survived without having a tumor relapse (mean survival = 53 months) revealed DNA grades below 1.00. Additionally, the DNA-malignancy-grade was closely correlated with the histopathologic malignancy grades.

Adult↗

PubMed1989

[Dysesthesia and anesthesia of the mandibular nerve following dental treatment].

An inquiry to all practising dentists of Schleswig-Holstein and Cologne was performed to estimate the incidence of long time lingual nerve damage. 50 cases were reported and analyzed according to findings and causes. Further on the Cologne inquiry took into consideration 43 injuries of the n. alveolaris inferior. The results of the study allow a statement on the necessity to inform the patient before the operation.

Adolescent↗

PubMed1989

[Management and treatment of patients with atypical facial pain].

The term "atypical facial pain" refers to a pain disease and should not be used for pain of peripheral origin. As a rule atypical facial pain is induced by a peripheral tissue trauma not necessarily associated with nerve lesions. The intensity of pain does not correlate with the measurable magnitude of the trauma. If treatment is possible, it will be the more successful the earlier it is started. Therapy comprises transcutaneous electric nerve stimulation, sympathetic nerve block, drug therapy and psychotherapy.

Adult↗

PubMed1988

Reconstruction of the mandibular denture bearing area and freeing of the tongue after tumor surgery.

Vestibuloplasty together with a loosening of the tongue and covering the mucosal defects either with a split thickness skin graft or an autologous mucosal graft was performed on 35 patients previously treated for squamous cell carcinoma. The interval between tumor resection and the reconstructive procedures averaged 20 months. In 34 patients the denture bearing area improved, and in 31 patients, better mobility of the tongue occurred with, therefore, better phonation.

Adult↗

PubMed1988

[A non-specific vulvo-vagino-gingival syndrome].

The case of a 29 year-old patient is reported who initially complained about gingivitis and one year later developed a colpitis. After two years the patient was admitted to our hospital where inflammatory erosive changes of the gingiva, the vagina and the vulva were seen. Neither laboratory parameters nor histological results allowed an exact diagnosis of these findings. Also a Lichen ruber erosive had been excluded by the microscopic findings of a gingival and vaginal biopsy. Thus, the diagnosis of a non-specific vulvo-vagino-gingival syndrome was established, whereby antiphlogistic treatment with corticosteroids led to an improvement of the patient's symptoms.

Adult↗

PubMed1987