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Biomedical subjects

B Hoffmeister

Publications and source records attributed to B Hoffmeister.

At least 37 records · Page 2Linked to original sources
PubMed1994

[Three-dimensional surgical planning using a model--a critical overview of the current status].

In the department of Oral and Maxillofacial Surgery, Kiel, 120 individual skull models have been fabricated from 1986 to 1992. The purpose of this study is to compare the results of the 3-D-operation simulation with those of the operation planning based on clinical, radiological and cast analyses. 62 models, used for simulation of skeletal reconstructions, osteotomies and transplantation of bone, have been analysed. In 38 cases the previous operation planning could be proved by the model operation. 24 operation simulations, including secondary reconstructions of the midface and the mandible, asymmetric craniofacial anomalies and large transplants of bone, lead to more exact results as the planning without a model. We therefore regard these types of operations as good indications for 3-D-model operation planning.

Bone Transplantation↗
PubMed1994

[Intraoral approach to mandibular reconstruction in surgery of benign tumors].

Nowadays the exclusive intraoral approach is standard in the operative treatment of mandibular fractures. However there is still scepticism in the selection of the intraoral approach for mandibular reconstruction. Between 1980 and 1992 we performed in 21 patients mandibular reconstructions by rib or iliac bone grafts after resections of benign tumors in the mandible. One transplant was lost, the remaining transplants were incorporated without problems. According to our results the exclusive intraoral approach of primary mandibular reconstructions by free bone-grafts after removal is a reliable procedure.

Adolescent↗
PubMed1992

[The gingival margin incision as the surgical approach in cleft jaw osteoplasty--the technic, the healing process and postoperative complications].

Marginal incision became a common surgical approach in periodontal surgery because of its good healing results. Since 1983 we use this incision for bone grafting in cleft palate patients. Out of 120 cleft palate patients which had marginal incision for bone grafting, 9 developed local dehiscence, 3 times in combination with partial loss of the cancellous bone transplant. We saw one total loss of the transplant caused by infection. The good results of primary wound healing, the absence of horizontal scars and the possibility of mobilisation of epithelium from the cleft region to cover the transplant with mucosa from the alveolar process are the advantages of this procedure.

Adolescent↗
PubMed1991

A proposed relationship between circumference and conduction velocity of unmyelinated axons from normal and regenerated cat hindlimb cutaneous nerves.

Data on the conduction velocities and circumferences of unmyelinated axons in cat hindlimb nerves obtained in two laboratories, each working independently of the other, have been brought together and compared. Results were obtained from normal, regenerated and deafferented nerves. Matching the conduction velocity and circumference distributions against one another suggested that conduction velocity (theta), in m/s, is linearly related to circumference (s), in microns, according to the equation theta = 0.24s. If this relationship is correct, it applies equally well to both sympathetic postganglionic and unmyelinated afferent axons.

Animals↗
PubMed1991

[Influence of different local anesthetics on the in vitro collagen synthesis of periodontal fibroblasts].

The influence of different local anesthetic fluids in an in-vitro-experiment of periodontal ligament cells was researched. Mepivacain, articain, lidocain and prilocain were used in the study. The common commercial local anesthetic fluids were in a proportion 1:1, 1:10 and 1:30 diluted, before they were placed in the incubator with cultures of periodontal ligament cells. At the 1st and 14th day after the experiment the synthesis of collagen type I, III, V and VI were determined with an ELISA. The mepivacain dilution of 1:30 had, compared with the controls the slightest influence on the collagen synthesis of periodontal ligament cells. Further clinical investigations must show if through dilution of the local anesthetic solution an adequate anesthesia can be reached.

Adult↗
PubMed1991

[Morphological changes of peripheral nerves following intraneural injection of local anesthetic].

Neurosensory disturbances of the third branch of the trigeminal nerve occur in rare cases without any operative treatment near the nerve involved. The most frequently affected nerve branches are the inferior alveolar nerve and the lingual nerve. We examined the problem of intraneural injection of local-anaesthetic solutions in an experimental study on animals. After intraneural injection of Articain (4%)-solution in the ischiadic nerve of Wistar rats and the lingual nerve of cats no toxic lesions were observed. It can be assumed that neurosensory disturbances caused by intraneural local-anaesthetic injection are the result of intraneural haematomas with consecutive fibrosis.

Animals↗
PubMed1991

[The subciliar incision as an infraorbital approach in caring for midface fractures].

As an infraorbital approach in the operative treatment of fractures of the midface, the zygoma and the orbital floor, the transconjunctival, the subciliar, the median eyelid and the orbital rim incision were proposed. In the Department of Oral- and Maxillofacial Surgery of the University Hospital Kiel we use the subciliar access to the infraorbital region. Between 1983 and 1988 105 subciliar incisions were performed in 448 traumatologic operative procedures. In the clinical follow-up examinations of 52 patients merely three of the cases presented dissatisfying results. We regard this type of incision to represent a favorable approach to the infraorbital region. Disturbing scar formation can principally be avoided.

Follow-Up Studies↗
PubMed1990

Reinnervation of autotransplanted teeth. A histological investigation in monkeys.

The reinnervation of 8 autotransplanted teeth in 4 green vervet monkeys (Ceropithecus aethiops) was examined. The lateral maxillary incisors of each animal were extracted and transplanted to the contralateral side. The root formation was incomplete with an open apical foramen. The monkeys were killed 1, 2 or 4 months after transplantation and examined histologically by a S-100 monoclonal antibody staining. A few single nerve fibres could be seen 1 month after transplantation. After 2 months, several nerve bundles could be detected throughout the whole pulp. After 4 months, a larger number of nerve bundles, comparable to the densely innervated dental pulp of non-transplanted teeth, could be seen throughout the whole pulp.

Animals↗
PubMed1990

Induction and upregulation of adhesion receptors in oral and dermal lichen planus.

The expression pattern of well-defined cell surface adhesion receptors called VLA-family, LFA-1 and ICAM-1 was determined semiquantitatively in biopsies of oral (n = 12) and dermal lichen planus (n = 5) and compared to normal uninvolved human oral mucosa (n = 12) and skin (n = 12) using an indirect immunoperoxidase technique. In both oral and dermal lichen planus, an induction of the beta 1-integrins VLA-1 and VLA-3 and an upregulation of VLA-6 was found in T cells infiltrating the basement membrane zone. These cell surface molecules function as receptors for collagen, fibronectin and laminin. A focal induction of ICAM-1 on basal keratinocytes could be detected at sites of intramucosal T cells. These results suggest that investigated adhesion receptors are crucially involved in the aggregation of T cells in both conditions. Further investigations have to be done to determine the functional role of these adhesion receptors in lichen planus.

Antigens, CD↗
PubMed1990

[Treatment concept of tumor-induced maxillofacial pain].

From 1987 to 1989 forty-six patients with primary or recurrent maxillofacial tumors which could not be treated curatively came to our clinic because they suffered for facial pain. Their treatment was carried out in cooperation with the pain clinic of the department of anesthesiology. In 8 patients causal therapy with palliative chemotherapy primarily carried out on an outpatient basis was successful. In the other patients oral application of opiates was the therapy of choice. In only few cases invasive techniques were required to relieve facial pain.

Facial Pain↗
PubMed1990

[Indications for plate osteosynthesis in childhood].

Miniplate osteosynthesis has become the method of choice in the surgical treatment of fractures in adults. The question arises whether or not miniplates should be used more frequently for childhood fractures as well. A clinical and experimental study of 121 fractures during the growth period was conducted to determine the criteria guiding the decision for the use of miniplates. Test in which miniscrews were unscrewed from fresh cadaver jaw bone showed that sufficient retentive forces for fracture stabilization can be achieved even with very short screws (5 mm). Miniplate osteosynthesis can also be applied in the treatment of mandibular fractures during the growth period from the eighth year of life onward.

Bone Plates↗
PubMed1990

[Sonographic diagnosis of mandibular fractures in children].

We investigated the possibilities of sonographic diagnostics of bone fractures in a clinical study. 18 patients with fractures of the lower jaw were examined. The technical procedure and typical symptoms are described. The sonographic analysis shows fractures with dislocations greater than 1 mm. Today it is not possible yet to exclude a fracture by sonographic diagnosis alone.

Adolescent↗