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Biomedical subjects

B Hammer

Publications and source records attributed to B Hammer.

At least 109 records · Page 6Linked to original sources

Free sequestered disc herniation at the S2 level misdiagnosed as neuroma.

The case of a 38 year-old-man with a mass at the S2 level similar to a benign nerve root tumor (neuroma) is reported. The CT scan examination revealed the mass close underneath but not in connection with a disc herniation at the L5/S1 level. During operation the mass was not encountered as tumor but as free sequestered disc herniation, which was confirmed by histological examination. The reasons for considering the mass a tumor are discussed.

Adult↗

[Facial injuries in bicyclists: epidemiological analysis and prophylactic consequences].

Bicycle accidents in adults are common and concern frequently injuries to head and face. 150 of totally 216 patients with cycle accidents in a six month' prospective study at the Basel University Hospital showed face and head trauma. 85 severe facial injuries treated operatively by the Clinic for Reconstructive Surgery between 1985 and 1989 are analysed in detail. These facial injuries are rarely life threatening and normally the postoperative outcome is good. Nevertheless, usual bicycle helmets cannot avoid facial trauma. Therefore traffic educational programs are the most important prophylactic efforts. Technical progress and improvement of the bicycles ask for better trained cyclists. Further more, the importance of really respecting the traffic rules as well as the construction of separate cycle routes is stressed.

Accidents, Traffic↗

[Structural and biomechanical based differences of osteosynthesis in mandibular or mid-face fractures. Why does the AO still use stiff plates?].

The mandible and the midface differ considerably in their anatomic structure, and therefore require different techniques for fracture stabilisation. Midface-fractures are stabilised by mini-plates, which are arranged in a three dimensional fashion. Fractures of the mandible require stronger plates because the osteosynthesis is done in only one plane.

Adult↗

[Endoscopic sclerosing treatment of acute hemorrhages (Forrest I) in the upper gastrointestinal tract].

For a duration of three years, endoscopic hemostasis was carried out in the Department for Gastroenterology at the State Hospital of the Canton of St. Gall on 20 patients suffering from acute upper gastrointestinal hemorrhage. 13 cases were of the hemorrhage type Forest IA, seven cases of the type Forest IB. By way of injecting adrenalin and/or Polidocanol, in all cases an initial hemostasis and in 80% of the cases a definite effect was attained. We judge the injection-method to be a simple, effective and inexpensive way of stopping hemorrhage. This method helps to avoid operating on high-risk patients to stop hemorrhage in the upper gastrointestinal parts.

Adult↗

Sucralfate in the treatment and prevention of gastric ulcer: multicentre double blind placebo controlled study.

A randomised controlled multicentre trial was performed in 160 patients with gastric ulcer, proved by endoscopy and biopsy, to compare ulcer healing with sucralfate and ranitidine (double blind double dummy design) and to assess the effect of maintenance treatment with sucralfate on ulcer recurrence (double blind placebo controlled design). The healing rates were similar with 4 g sucralfate suspension per day and 300 mg ranitidine per day (82% and 88% after 12 weeks, respectively). Of the 109 patients with healed ulcers, 92 were entered into the maintenance trial and treated with sucralfate tablets (2 g per day) or placebo tablets. Maintenance treatment with sucralfate delayed symptoms of gastric ulcer recurrence. Lifetable analysis showed significant differences between sucralfate and placebo, both after six months (p = 0.018) and after 12 months (p = 0.044). The rates of symptom recurrences were 13% and 34% after six months and 34% and 55% after 12 months for sucralfate and placebo, respectively. The rate of asymptomatic recurrences after 12 months was similar in the two groups (9% and 10%, respectively). The recurrence rate was higher in patients who had never taken non-steroidal anti-inflammatory drugs than in those who had but had stopped on admission to the study. It was also higher in patients with recurrent ulcer and in those with scarring deformation and narrowing of the pylorus. Maintenance treatment with sucralfate slowed the appearance of symptom recurrences of gastric ulcer.

Adult↗

[Therapy of pyogenic liver abscess].

Between 1980 and 1986, 11 patients with pyogenic liver abscess were treated at the Department of Internal Medicine at the Kantonsspital St. Gallen. 2 patients underwent successful surgical drainage and 9 patients percutaneous needle aspiration or drainage. 7 were successfully treated while 2 required secondary surgical drainage. Our results suggest that percutaneous aspiration or drainage of pyogenic liver abscess should be tried before surgery is considered.

Adult↗

Burkitt's lymphoma protruding through the anus. Report of an unusual case.

A four-year-old boy had a cecoanal intussusception prolapsing through the anus. A 4 x 4 cm cecal tumor served as the leading point of the intussusception. Laparotomy and histology revealed that the tumor was a solitary Burkitt's lymphoma of the cecum. Isolated Burkitt's lymphoma, as presented here, is rare, and such a combination has never been reported. Intussusception prolapsing through the anus and Burkitt's lymphoma are discussed, as well as a possible reason for the rarity of the condition.

Burkitt Lymphoma↗

Gastric ulcer: a double blind comparison of 800 mcg misoprostol versus 300 mg ranitidine.

Seventy-nine patients with endoscopically confirmed gastric ulcers received either ranitidine (37 patients) or misoprostol (42 patients) in a randomized double-blind manner. Fifty-six percent of the patients treated with ranitidine, and 38% of those treated with misoprostol presented with endoscopically healed ulcers after four weeks of treatment. After eight weeks complete healing had occurred in 86% of the patients receiving ranitidine, and 74% of those on misoprostol. These differences were not statistically significant. In smokers, ranitidine was superior to misoprostol, leading to a higher healing rate at four weeks (73% versus 20%). Thus there was no evidence that in patients with gastric ulcer misoprostol overcomes the negative effect of cigarette smoking.

Adult↗

[CT follow-up of neurocysticercosis treated with praziquantel].

Praziquantel therapy has produced a much better prognosis in neurocysticercosis since 1980. The computed tomographic findings and follow-up study in 4 patients with neurocysticercosis before and after praziquantel therapy are described. The special difficulties of differential diagnosis and further diagnostic procedures are discussed in cases in which calcifications are absent and only solitary foci can be found.

Adult↗

[Therapy of stomach ulcer with sucralfate and ranitidine. A multicenter double-blind study].

134 outpatients with acute benign gastric ulcer confirmed by endoscopic biopsy received either 1 g sucralfate suspension four times daily or one 150 mg ranitidine tablet twice daily for six to 12 weeks in a multicentre therapy study (double-blind study according to the double-dummy technique). After six to 12 weeks, respectively, 56% and 82% of the ulcers had healed in the sucralfate group. The rates of healing in the ranitidine group were 72% and 88%, respectively. The differences in the rates of healing between sucralfate and ranitidine were not statistically significant. Ranitidine was superior to the sucralfate suspension in corpus ulcer. In the distally located ulcers, the two kinds of treatment were equivalent. There were no appreciable differences between the medications with regard to antacid consumption and compliance. Gastric pain was influenced better by ranitidine than by sucralfate.

Antacids↗

[Continuous ECG in colonoscopy].

42 patients aged over fifty years underwent continuous electrocardiographic monitoring before preparation for colonoscopy, after preparation and during and after colonoscopy. After preparation 11 patients, and during colonoscopy 12 patients, showed no electrocardiographic abnormalities. 31 patients developed or had increased electrocardiographic abnormalities after preparation and 30 patients during colonoscopy. There was no difference in the frequency of electrocardiographic abnormalities after preparation for colonoscopy and during colonoscopy. 68% of the 19 patients with previously diagnosed heart diseases had arrhythmias after preparation and 47% during colonoscopy, and they were thus significantly more frequent than in patients without heart diseases. Serious forms of arrhythmias also occurred more often in patients with heart diseases. None of the arrhythmias observed produced clinical symptoms or complications. Electrocardiographic monitoring during the whole length of preparation and during colonoscopy for all patients with heart diseases does not appear technically feasible. We therefore recommend it for patients with very severe heart diseases only.

Aged↗

[Ranitidine therapy of duodenal ulcer: comparison of once-a-day and twice-a-day administration. A Swiss multicenter double-blind study].

In a Swiss multicenter double-blind trial ranitidine was given in doses of 300 mg nocte and 150 mg b.d. for the treatment of duodenal ulcer. Ninety-seven patients with endoscopically proven ulcer were treated for four, and in cases of non-healing for eight, weeks. Cumulative healing rates with 300 mg and 2 X 150 mg were 77% and 78% after four weeks and 90% and 94% after eight weeks respectively. 60 and 65% of the patients were asymptomatic after four weeks. Smoking did not adversely affect healing. Thus, ranitidine in a dose of 300 mg nocte is as effective as ranitidine in a dose of 150 mg b.d. in the treatment of duodenal ulcer.

Adolescent↗

[The value of early postoperative CT study after lumbar intervertebral disk surgery].

The changes of the early intraspinal conditions few days after an operation of a lumbar disc herniation are little known. We, therefore, examined these operation areas by CT on a representative group of 256 patients. Besides the "common" findings, such as seroma, one must classify conditions such as haematomas, isolated bone fragments and/or residual disc tissue as "unusual" changes. The CT findings are correlated with clinical symptoms. We conducted CT and clinical follow-up studies in 91 patients several weeks later. All patients showed epidural scars of very different intensity. The comparison between early postoperative findings and the controls documents the high accuracy of the interpretation of the early postoperative states seen by CT. Therefore, it is possible to give hints for the indication for early postoperative CT examinations, for the prognosis as well as for the technique for a safe operative procedure.

Female↗

Budd-Chiari syndrome in sarcoidosis.

A 34-year-old previously healthy woman presented with bilateral interstitial lung changes and thrombotic occlusions of the hepatic veins. A transcaval wedge resection of the liver and a hepato-caval anastomosis were performed. This operation reestablished the impaired intrahepatic venous flow and relieved the portal hypertension and the associated symptoms. Histopathological examination of both liver and lung tissues revealed noncaseating granulomas without microorganisms, confirming the suspected diagnosis of sarcoidosis. The hepatic veins were demonstrated to be narrowed by sarcoid granulomas forming the mechanical basis for venous stasis and extensive thrombotic occlusions. To our knowledge only one other case of a Budd-Chiari syndrome occurring in a patient with sarcoidosis has been reported.

Adult↗