The detection of metastatic disease of the spine in oncology patients using MRI.
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Adult↗
Biomedical subjects
B Hale
Publications and source records attributed to B Hale.
Sleep-waking pattern and body temperature in hypoxia at selected ambient temperatures.
We studied the effect of mild hypoxia (15% O2) and low ambient temperature (Ta = 15 degrees C) on the rat's sleep-waking pattern (SWP) and maximum-minimum core temperature (max-min Tb). Mild hypoxia at neutral Ta (29 degrees C) disrupted the SWP in the same way as low Ta during normoxia: both affected the pattern of frequency of state changes (P less than 0.01), not the pattern of epoch durations. Mild hypoxia and low Ta together caused a degree of disruption of the SWP which was the sum of each alone, i.e., additive. Although both mild hypoxia and low Ta significantly depressed max-min Tb, low Ta exerted a greater effect than mild hypoxia. Together they further depressed max-min Tb in an additive way. We conclude that mild hypoxia disrupts the rat's SWP independent of central thermoregulatory mechanisms at neutral Ta, that the effects of mild hypoxia and low Ta on the SWP are additive at the stimulus levels used, and that Ta, not inspired O2, determines Tb.
Animals↗
The effects of hypoxia and CO2 on the sleep-waking pattern of the potoroo (Potorous tridactylus apicalis).
Four male potoroos (Potorous tridactylus apicalis) breathed 21% and 7% O2 with and without the addition of 5% CO2. The effects of these gas mixtures on the potoroo's sleeping-waking pattern (SWP) were studied. The SWP while breathing 21% O2/5% CO2 was unchanged when compared with that of breathing ambient air (21% O2). While breathing 7% O2, the SWP was severely disrupted: total sleep time (TST) and slow wave sleep (SWS) increased markedly. Brain temperature fell substantially. Paradoxical sleep (PS) was almost abolished and wakefulness (W) decreased. The addition of 5% CO2 to the O2 deficient gas mixture, i.e., 7% O2/5% CO2, restored the SWP to that obtained while breathing ambient air. It is concluded that CO2 neutralizes the disruptive effect which hypoxia has on the potoroo's SWP. It is hypothesized that this constitutes a homeostatic mechanism for stabilizing the SWP and is carried over from pouch life.
Animals↗
Appearances can be deceiving...in Mr. Langley's case, they were shocking, too.
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Aged↗
Congenital dysplasia of C2--6.
Neural arch dysplasia of the cervical vertebrae is a rare occurrence. The authors present a case with dysplasia of cervical bodies and posterior arch elements at multiple levels. The embryogenesis of these anomalies is discussed.
Adolescent↗
Children with recurrent abdominal pain: how do they grow up?
The results of treatment by reassurance and explanation of 30 children with recurrent abdominal pain have been compared with those in a group of 30 children seen earlier and given no such treatment. Most of the 19 treated children who responded to treatment did so more quickly than the untreated ones, and relapse did not occur in the treated group.
Abdomen↗