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Biomedical subjects

B Fraysse

Publications and source records attributed to B Fraysse.

At least 55 records · Page 3Linked to original sources

Selection criteria for cochlear implants in children.

OBJECTIVE: To determine the selection criteria for cochlear implantation in children. SETTING: Hospital pediatric implant center. PATIENTS AND INTERVENTIONS: Selection of patients depends on medical evaluation, audiometric data, speech discrimination, communication skills, cognitive skills, and psychosocial factors. Patient selection is based on tonal audiometry, computed tomography, magnetic resonance imaging, and electrophysiologic tests. Side of implantation is chosen according to cochlear structure, duration of deafness, and dominant handedness. RESULTS: Ninety-eight cochlear implantations with the Nucleus multichannel implant have been performed at this center since 1990. CONCLUSION: The selection of children for cochlear implantation require close collaboration between the pediatric surgical team, the educational team, and the family.

Auditory Threshold↗

[Cochlear implants in the elderly].

The authors present a retrospective and multicenter study of 18 elderly patients aged above 60 years-old who underwent a cochlear implantation by comparing them with a population of adult patients. The purpose of this study is to evaluate the utility and benefits of cochlear implantation in the elderly by analyzing the clinical data and the results of a questionnaire assessing the use of the implant and the consequences of implantation on the quality of life. The results of this study indicate that the improvement of quality of life in the elderly is similar compared to a control group of adult patients.

Aged↗

[Conservation of residual hearing after cochlear implantation].

Indications for cochlear implantation have been expanded to include severely hearing impaired adults and may increase the number of patients presenting with preoperative residual hearing. Conservation of residual hearing may allow better performance with an implant. However, conventional thought is that implantation destroys auditory structures involved in residual hearing. This study was undertaken to assess if there are general or surgical factors intervening in the conservation of residual hearing in a sample of multichannel implant recipients. A retrospective study on 50 adult cochlear recipients with preoperative residual hearing has been undertaken. Sixteen of 50 implanted subjects (32%) were found to have conserved their residual hearing. Among them, seven patients have clinically non-significant changes of hearing. Age, side of implantation, gender and etiology did not influence the outcome of residual hearing. Round window ossification, ossification of the cochlea, length of insertion, approach and site of insertion (scala tympani vs.scala vestibuli) were not found to be statistically significant between the population having lost and the population having conserved residual hearing. This study emphasizes the need to undertake a larger multicenter longitudinal study to determine the existence of factors related to the conservation of residual hearing.

Adolescent↗

Histopathology of the peripheral vestibular system in small vestibular schwannomas.

Gadolinium-enhanced magnetic resonance imaging can be used to detect small vestibular schwannomas/acoustic neuromas. Early detection raises the question of the necessity of their surgical removal. Do all tumors induce lesions in the vestibule and to what extent? We thus investigated the ultrastructure of peripheral vestibular systems in grades I and II schwannomas. Vestibular tissues were fixed as soon as they were removed during the resection of tumors, by the translabyrinthine approach, and then processed for transmission electron microscope observations. In neurosensory epithelia, hair cells lost stereocilia, whereas cuticular plates disaggregated. The cytoplasm of hair cells degenerated in either a dense or vacuolated manner, and cytoplasmic blisters extended into the endolymph. In some cases, supporting cells extended processes covering the apical surface of hair cells. Nerve fibers massively disappeared from epithelia, only few nerve fibers contacted type I and type II hair cells, and both afferent and efferent terminals were abnormal. In vestibular nerves, axons degenerated, and myelin sheaths disaggregated. Glycogen was present in both intracellular and extracellular spaces. Luse bodies associated with collagen bundles were found between fibers. Scarpa ganglion neurons contained lysosomes/lipofuscin granules and vacuoles. Tumor cells were found in both the ganglion and the vestibular nerve. Thus small tumors induce extensive degeneration of vestibular tissues. The various hallmarks of schwannomas are already present in small acoustic neuromas. Moreover, different types of degeneration of hair cells and neurons were observed, together with the covering of hair cells by supporting cells and the accumulation of glycogen in the vestibular nerve.

Adult↗

Comparison of postoperative results in suspected and confirmed cases of perilymphatic fistula.

Perilymphatic fistula is suspected on clinical symptoms, but must be confirmed by surgery. Exploratory tympanotomy was realized in 38 patients, presenting one or several symptoms of perilymphatic fistula. A leak was observed in 23 patients (61%). When a leak was not observed, the oval and round windows were filled with connective tissue. Preoperative and post-operative symptoms were compared in patients with or without leak: there was not significant difference between the two groups of patients. 63% of patients presenting fluctuant or sensorineural hearing loss improved or stabilized hearing after surgery. One patient, presenting a post-traumatic total deafness due to round window rupture, was immediately operated on, and recovered normal hearing. 84% of patients with vertigo or dizziness improved after surgery. The authors conclude that exploratory tympanotomy should be widely proposed when a perilymphatic fistula is suspected. Oval and round window should be grafted with connective tissue even if a leak is not observed.

Adolescent↗

Rehabilitation of long-term facial paralysis.

A wide variety or techniques have been developed over the years in an effort to reduce the devastating impact of facial paralysis on the patient. The authors choose to perform hypoglossal-facial nerve anastomosis when facial facial nerve anastomosis, or cross-over, or microvascular muscle transplantation are impossible. Nevertheless, these results appear always insufficient for palpebral occlusion. The authors propose to associate two rehabilitation technique to obtain optimal results. They perform hypoglossal facial nerve anastomosis using the technique modified by U. Fisch, and they associate temporal muscular transfer to improve ocular protection. This association imposes an increased strain on the patient in an effort to undertake double re-education which modifies twice his classic corporeal scheme. The surgical technique are associated after evaluation of the possibility of the patient adherence to the long duration physical therapy.

Anastomosis, Surgical↗

Criteria for selecting the side for cochlear implantation.

Choice of the side for cochlear implantation should take into account peripheral (extracortical) factors and central (cerebral dominance) factors. From 111 patients implanted with a Nucleus device, the authors found that significant peripheral factors were the degree of cochlear ossification, the duration of deafness before cochlear implantation, and the preoperative promontory test dynamic range (degree of response on the promontory test in decibels); cause of deafness and residual hearing were not correlated with speech discrimination. Cerebral dominance was indirectly determined by handedness. Handedness laterality was determined by a questionnaire. There was no significant difference in results between patients implanted on their dominant side and patients implanted on their nondominant side. When ears are different according to their peripheral factors, the authors suggest implanting the better ear, provided there is no significant hearing in that ear. When both ears are identical, the side of implantation should be the side of handedness laterality to facilitate device manipulation (a practical reason).

Adolescent↗

[Vertigo in non-vascular diseases of the central nervous system].

Excluding vascular involvement, vertigo due to a central vestibular syndrome reflects a median or paramedian lesion of the brain stem or the cerebellum. Recurrent attacks of vertigo usually occur with peripheral lesions. Persistent acute vertigo with peripheral destruction can reveal ischemia of the brain stem. Central positional vertigo is rare and has symptomatology that is different from that of benign positional vertigo. Persistent instability has a symptomatology that is more difficult to analyse and is usually associated with a central vestibular syndrome when it is organic. Diagnosis of a central vestibular syndrome is based on detection of well-defined clinical or electronystagmographic signs of which abnormal nystagmus is primordial. Some of them such as inferior vertical nystagmus or dissociated nystagmus can localise the site. MRI has become the diagnostic procedure which is best adapted for identifying the most frequent aetiologies such as tumors, congenital malformations and multiple sclerosis.

Central Nervous System Diseases↗

Histiocytosis X of the petrous bone in the adult: MRI.

Two cases of histiocytosis X in young adults with involvement of only the petrous bone are reported. In the first symptoms and signs consisted of a seventh nerve palsy of gradual onset over 3 years, and in the second, of pulsatile tinnitus associated with otorrhoea of clear fluid and impaired vestibular function. CT revealed large lytic lesions of the petrous bone. T1-weighted MRI before and after gadolinium confirmed the presence of a mixed tumour of the petrous bone with marked uptake of contrast medium. Spin echo images demonstrated the absence of extradural extension, and the patency of the arterial and venous network, therefore enabling differential diagnosis from extensive glomus jugulare tumours.

Adolescent↗

Intraoperative facial nerve monitoring in posterior fossa surgery: prognostic value.

A retrospective study was done of 43 patients operated on for acoustic neuroma by a translabyrinthine approach with intraoperative facial nerve monitoring. Direct stimulation of the facial nerve at the level of the cerebellopontine angle (CPA) and the internal auditory canal (IAC) permits the calculation of a R ratio that has a predictive value for postoperative facial function: R = R'/R'', where R' is the ratio of the minimal intensity (I) of stimulation capable of inducing a response after direct stimulation of the facial nerve at the level of the CPA over the electromyographic response amplitude (A): R' = I(CPA)/A(CPA), R'' being equal to the ratio of these same measurements after stimulation at the IAC: R'' = I(IAC)/A(IAC). Statistical analysis has shown that an R ratio </= 2 has a favorable prognostic value on facial mobility whereas an R ratio > 2 permits the supposition of an alteration of facial function. This prognostic value is more precise if the R ratio is co-related to the macroscopic aspect of the facial nerve at the end of surgery.

Journal Article↗

[Surgical technique and results of cochlear implant in normal or ossified cochlea].

The authors describe the surgical technique and results of the Nucleus device in 50 recipients. Cochlear ossification was present in one third of patients. Total insertion was possible in all cases with a partial ossification (< or = 8 mm), and once in a case with a total ossification (> 8 mm) of the scala tympani of the basal turn. Results were not significatively different in normal cochleas and in ossified cochleas. The authors describe a per-operative algorithm in front of a basal turn ossification, emphasizing on the insertion in scala vestibuli through the oval window. According to the results, the authors prefer the use of a multi-channel cochlear implant than a monochannel implant, even in ossified cochleas.

Adolescent↗

[Value of auditory evoked potentials and electrocochleography in the diagnosis of small acoustic neuromas. Our experience on 131 cases].

The auditory brainstem responses, in a series of 131 patients with surgically confirmed acoustic neuroma, are reported. Six groups have been individualized according to the value of the I-V interpeak latency, the synchronisation of the waveform shape and the need to perform an electrocochleography. If we exclude the sixteen cases of profoundly deafness, or cophosis, where ABR and ECoG don't permit the recording of waves, the electrophysiological investigations allowed to provide the diagnosis of retrocochlear lesion in 115 patients, for a rate of 98.26%. This high degree of sensitivity favorably with data reported in literature, and supports the reliability of this method for detection of acoustic neuroma. According to these results, our diagnosis workup of a patient suspected of having an acoustic neuroma, presenting normal ABR findings, is presented.

Aged↗