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Biomedical subjects

B Fleming

Publications and source records attributed to B Fleming.

35 records · Page 2Linked to original sources
PubMed1989

A biomechanical analysis of the Ilizarov external fixator.

Five configurations of the Ilizarov fixator were analyzed in vitro. The overall stiffness, shear stiffness, and axial motion of the fracture site were determined. The data were compared with the results of eight conventional one-half frame fixators previously tested in the same manner. The Ilizarov fixator allowed significantly more axial motion at the fracture site during axial compression than the other fixators tested. The overall stiffness and shear rigidity of the Ilizarov external fixator were similar to those of the one-half pin fixators in bending and torsion. The stability of the Ilizarov fixator was a function of bone position within the fixator rings and fixation wire tension. The use of olive stop wires increased the shear resistance of the Ilizarov system.

Biomechanical Phenomena↗
PubMed1988

Total knee arthroplasty kinematics. An in vivo evaluation of four different designs.

Thirty-four patients who had 42 total knee arthroplasties during the past 5 years were examined. Four types of total knee arthroplasties (Tricon-M, PCA, Variable Axis, and Anametric) were evaluated, using a computerized knee evaluation system. The patients and 10 controls with normal knees were tested for anteroposterior stability with the Lachman test, medial/lateral stability at 20 degrees, varus/valgus stability at 20 degrees, internal/external rotation at 80 degrees and 20 degrees of flexion, and internal/lateral rotation (screw home) over the active range of motion. At 30 degrees of flexion, the Variable Axis prosthesis was 54% more constrained than the normal knee to anterior/posterior shear. The Anametric and the Variable Axis were more lax under varus/valgus stress than the normal knee by 85% and 71%, respectively. There were no statistical differences for any of the other tests.

Aged↗
PubMed1987

Factors associated with compliance in the follow-up treatment of alcoholism.

This study examined factors associated with compliance in the follow-up treatment of alcoholism. Twenty-five patients who dropped out of treatment within six months were compared with 25 patients who completed a two-year treatment programme. The two groups were compared for socio-demographic factors and personality traits using the EPI and Cattell 16PF. Personality traits did not discriminate between the two groups. However, as in previous studies significant correlation between low socio-economic class and dropping out of treatment was found. Marital instability and a family history of alcoholism also tended to correspond with dropping out of treatment although the tendency was not statistically significant.

Adult↗
PubMed1982

T-cell-dependent polyclonal activation by soluble mycobacterial extracts of B cells in peripheral blood mononuclear cell populations from leprosy patients and normal donors.

Soluble extracts of ultrasonically disrupted mycobacteria (including Mycobacterium leprae) cause strong T-cell-dependent, Cyclosporin A-sensitive, polyclonal B-cell activation, in human peripheral blood mononuclear cell preparations. It is not enhanced by cortisol. Cells from cases of lepromatous leprosy show no polyclonal B-cell activation in the presence of extracts of M. leprae, although they respond normally to other mycobacterial species. The polyclonal B-cell activation response to the M. leprae extract, of a small group of normal leprosy contacts, was reduced relative to that of non-contacts.

Adult↗
PubMed1977

Effects of degree of obesity, age of onset, and weight loss on responsiveness to sensory and external stimuli.

Four experiments tested responsiveness to external and sensory stimuli in female human subjects who differed in degree of overweight and in age of onset of their obesity. The effects of weight loss upon external responsiveness were assessed by testing subjects before and after weight reduction in order to determine the role of energy deficit and deprivation in mediating heightened responsiveness to external cues. There was no significant positive correlation between degree of overweight and degree of external responsiveness. In general, the age of onset of the obesity was also not a relevant factor in the degree of externality. Weight loss did not change responses to visual and cognitive cue salience manipulations in measures of feeding, emotionality, time perception, and short-term recall, whereas responsiveness to variations in palatability increased following weight reduction. While external cue responsiveness does not appear to result from adiposity per se or from deprivation, responsiveness to taste stimuli may reflect these parameters. The role of external and sensory cues in the development and maintenance of obesity is discussed.

Adolescent↗
PubMed1973

Time accelerating.

Explore the source record for details and available documents.

Electric Injuries↗
PubMedDate not supplied

Anterior cruciate ligament reconstruction using quadriceps patellar tendon graft. Part I. Long-term followup.

Eighty-three patients with ACL reconstructions using the quadriceps patellar tendon graft were evaluated in a 10 year (mean, 5.5 years) follow-up study. A five-part analysis, consisting of physical examination, questionnaire, Genucom analysis, operative note review, and radiographs, was performed. Seventy-six percent were categorized as satisfactory. Ninety-two percent were content with their results, while only 4% were unsatisfied. Ninety-three percent of the patients had no significant pain and 95% had no giving way postreconstruction. Ninety-two percent had no more than a mild functional deficit. Eighty-seven percent and 90% of the patients had no significant Lachman or pivot shift by examination, respectively. Our results showed no increase in failure over time (1 to 10 years), although those operated on during the initial 5 years showed more radiographic degenerative changes. Plotting our results in classification systems of other authors yielded success rates as good as or better than those using our own criteria. An objective means by which to quantify laxity did not reliably correlate with the quantifying of laxity made by physical examination. Only the lack of a formal rehabilitation program greater than 4 months postoperatively and repaired tears of the medial or lateral collateral ligaments proved to be significant risk factors for poor recovery.

Anterior Cruciate Ligament↗
PubMedDate not supplied

Anterior cruciate ligament reconstruction using quadriceps patellar tendon graft. Part II. A specific sport review.

Eighty-three patients, from a 10 year follow-up study, who underwent ACL reconstruction with a quadriceps patellar tendon graft were reviewed. A questionnaire qualifying their sports performance in 20 possible sports compared their preinjury status to postinjury and postreconstructive surgery. Successful and unsuccessful patients, as determined by our previous investigation, were likewise compared. Sports performance, regardless of the sport or level of competition, decreased substantially postinjury and then rose significantly to near but not equal to patient preinjury status. The most strenuous sports dipped to the lowest performance level after injury and returned with a correspondingly more modest gain after the reconstruction. Not surprisingly, successful patients had a more impressive return in performance than unsuccessful patients, mirroring their clinical grading. Of those deemed unsatisfactory (N = 20), graft failures were no worse off in performance rating than those that were classified as unsatisfactory because of persistent symptoms.

Anterior Cruciate Ligament↗
PubMedDate not supplied

Isometric versus tension measurements. A comparison for the reconstruction of the anterior cruciate ligament.

This study was designed to compare the displacement patterns of an isometer, used to determine graft placement during reconstruction, with the actual tensions on an anterior cruciate ligament substitute. In cadaveric specimens, a Kevlar anterior cruciate ligament substitute was implanted in three separate femoral sites, each of which was subsequently fixed to two different tibial sites. The initial tension of the Kevlar substitute was set to 22 or 33 N at 20 degrees of knee flexion. The displacement patterns for each position were recorded during passive flexion-extension using the isometer. Using a custom-designed tensiometer, the tensile forces on the substitute after rigid fixation at the tibia and femur were measured. During passive flexion-extension, the maximum change in tension of the anterior cruciate ligament substitute, measured by the tensiometer, was correlated with the maximum change in displacement between attachment sites, measured by the isometer. The coefficient of determination was equal to 0.15, indicating that the isometer may not accurately predict the tensions developed in the substitute.

Anterior Cruciate Ligament↗