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Biomedical subjects

B Dufour

Publications and source records attributed to B Dufour.

At least 109 records · Page 6Linked to original sources

[Cancer of the kidney with contralateral ureteral metastases (author's transl)].

The authors report a very unusual case of cancer of the kidney with contralateral ureteral metastases. The patient was treated by a right iliopelvic ureterectomy, enlarged left nephrectomy, and reestablishment of continuity by crossed anastomosis between the right lumbar ureter and the residual left ureter distal to the nephrectomy. An excellent functional result was obtained for 9 months after operation but death occurred from metastases.

Adenocarcinoma↗

[Reno-ureteral prosthetic by-pass operations : experimental results (author's transl)].

Results of experiments conducted in dogs are reported, in which the first few centimetres of the ureter were replaced by a prosthesis in silicone elastomer, the upper extremity being intubated by a trans-renal approach into the lower calyx and the upper extremity into the iliolumbar ureter. The one case of failure among the 6 dogs studied was due to a pyonephrosis from a technical error. In the 5 surviving dogs, the by-pass has remained permeable and there is no sign of incrustation. Control I.V.U. examinations after periods ranging from 26 months to 3 years showed normal function. This procedure has now been used in two human cases with good results.

Animals↗

[Ureterovesical and reno-ureteral prosthetic bypass operations : results after 3 years (author's transl)].

The author applied the results of a successful long-term experimental study in dogs by using ureteral prostheses in two patients, one with loss of pelvic ureteral substance after extensive hysterectomy for cancer of the cervix, and the other with loss of sub-pyelic ureteral substance. In the first case the prosthesis joined the iliac ureter to the bladder, and in the second case a lower calyx to the lumbar ureter. Follow-up of both cases after more than 3 years shows that in certain patients, chosen particularly, in whom no other method of ureteral replacement is possible, a ureteral prosthesis in silicone elastomer can be an acceptable procedure which can remain in place for long periods, more than 3 years in the cases reported.

Adult↗

["Suspended" segmental replacement of the ureter using the ileum. Experimental results at five years (author's transl)].

Segmental replacement of the ureter using an intestinal segment has given good long term experimental results. Preservation of the pelvic ureter has two advantages:--The use of a short intestinal loop, which decreases the secretion of mucus, stagnation and electrolyte reabsorption;--preservation of the normal uretero-vesical junction, thereby avoiding reflux. At the beginning of this experimental study, it was feared that the pelvic ureter would become obstructed by mucus and that the insufficiently contractile and atonic ileal loop would dilate, forming a "pool" of stagnant urine. In fact, no such complications were seen.

Animals↗

The prosthetic replacement of the ureter: experimental and clinical results.

The authors present their experience over several years in replacement of the ureter by a silicone prosthesis. This includes experimental work in dogs and clinical application performed in three different ways: (1) A uretero-vesical or pelvo-vesical bridge. Trials were started in 1967 and on the whole the results have been good, although in some cases deterioration was noted after a few months (18-20). The quality of the results obtained experimentally, encouraged clinical application and the authors employed ten prostheses in patients with advanced carcinoma and obstruction. The results have been excellent and a cutaneous fistula or diversion has been avoided. (2) Segmental replacement of the lumbo-iliac ureter. In experiments in 15 dogs, there were nine successful results, with survival periods of from 19 to 25 months. One patient has been treated with an immediate good result. (3) A renal-ureteric bridge. By implanting the top end of the prosthesis in the lower calyx and at the lower end in the lumbo-iliac ureter, the pelvis and proximal ureter are by-passed. This procedure has been applied in one patient. He has been followed up for only 4 months, but the results appear to be excellent.

Acute Kidney Injury↗